Search Results - "Pinas, N."

Synthesis and biological properties of the [5-( N5-dimethyl)-glutamine]-analogue of the C-terminal heptapeptide of substance p : Active-site studies by Pinas, N., Poulos, C.P., Theodoropoulos, D.

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Synthesis and contractile activity of the C-terminal heptapeptide of substance P with N5-dimethyl glutamine in the 6-position. Active site studies by Poulos, C P, Pinas, N, Theodoropoulos, D

“…The synthesis and testing of [N5-dimethyl-Gln6]-SP5-11 showed 37 +/- 12% contractile activity relative to SP, and intrinsic efficacy 98 +/- 4%. This finding…”
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Synthesis and biological properties of the [5‐(N 5‐dimethyl)‐glutamine]‐analogue of the C‐terminal heptapeptide of substance p by Pinas, N., Poulos, C.P., Theodoropoulos, D.

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Structure-activity studies on the C-terminal amide of substance P by Escher, Emanuel, Couture, Rejean, Poulos, Constantinos, Pinas, Nikos, Mizrahi, Jacques, Theodoropoulos, Dimitrios, Regoli, Domenico

“…Twelve C-terminal heptapeptide analogues of substance P have been synthesized by solid phase and by the classical solution method. The modifications concerned…”
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