Search Results - "Pinas, German E"

Identification of a Kinase-Active CheA Conformation in Escherichia coli Chemoreceptor Signaling Complexes by Piñas, Germán E, Parkinson, John S

“…chemotaxis relies on control of the autophosphorylation activity of the histidine kinase CheA by transmembrane chemoreceptors. Core signaling units contain two…”
Get full text

Hexameric rings of the scaffolding protein CheW enhance response sensitivity and cooperativity in Escherichia coli chemoreceptor arrays by Piñas, Germán E, DeSantis, Michael D, Cassidy, C Keith, Parkinson, John S

“…The chemoreceptor array is a supramolecular assembly that enables cells to respond to extracellular cues dynamically and with great precision and sensitivity…”
Get more information

Stress-triggered signaling affecting survival or suicide of Streptococcus pneumoniae by Cortes, Paulo R, Piñas, Germán E, Cian, Melina B, Yandar, Nubia, Echenique, Jose

“…Abstract Streptococcus pneumoniae is a major human pathogen that can survive to stress conditions, such as the acidic environment of inflammatory foci, and…”
Get full text

Acidic stress induces autolysis by a CSP-independent ComE pathway in Streptococcus pneumoniae by Pinas, German E, Cortes, Paulo R, Orio, Andrea G. Albarracin, Echenique, Jose

“…Departamento de Bioquímica Clínica-CIBICI (CONICET), Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Medina Allende y Haya de la Torre, Ciudad…”
Get full text

Subinhibitory concentrations of penicillin increase the mutation rate to optochin resistance in Streptococcus pneumoniae by Cortes, Paulo R., Piñas, Germán E., Albarracin Orio, Andrea G., Echenique, José R.

“…Objectives The aim of this work was to study the effect of subinhibitory concentrations of penicillin, chloramphenicol and erythromycin on the mutation rate of…”
Get full text

Characterization of In Vitro-Generated and Clinical Optochin-Resistant Strains of Streptococcus pneumoniae Isolated from Argentina by Cortes, Paulo R, Orio, Andrea G. Albarracín, Regueira, Mabel, Piñas, Germán E, Echenique, José

“…Optochin susceptibility is a key test used for pneumococcal diagnosis, but optochin-resistant (Optr) pneumococci have been reported in the last 2 decades. In…”
Get full text

The oxidative stress response of Streptococcus pneumoniae: its contribution to both extracellular and intracellular survival by Hernandez-Morfa, Mirelys, Olivero, Nadia B., Zappia, Victoria E., Piñas, German E., Reinoso-Vizcaino, Nicolas M., Cian, Melina B., Nuñez-Fernandez, Mariana, Cortes, Paulo R., Echenique, Jose

“…Streptococcus pneumoniae is a gram-positive, aerotolerant bacterium that naturally colonizes the human nasopharynx, but also causes invasive infections and is…”
Get full text

The source of high signal cooperativity in bacterial chemosensory arrays by Piñas, Germán E., Frank, Vered, Vaknin, Ady, Parkinson, John S.

“…The Escherichia coli chemosensory system consists of large arrays of transmembrane chemoreceptors associated with a dedicated histidine kinase, CheA, and a…”
Get full text

The pneumococcal two-component system SirRH is linked to enhanced intracellular survival of Streptococcus pneumoniae in influenza-infected pulmonary cells by Reinoso-Vizcaíno, Nicolas M, Cian, Melina B, Cortes, Paulo R, Olivero, Nadia B, Hernandez-Morfa, Mirelys, Pinas, German E, Badapanda, Chandan, Rathore, Ankita, Perez, Daniel R, Echenique, Jose

“…The virus-bacterial synergism implicated in secondary bacterial infections caused by Streptococcus pneumoniae following infection with epidemic or pandemic…”
Get full text

Networked Chemoreceptors Benefit Bacterial Chemotaxis Performance by Frank, Vered, Piñas, Germán E, Cohen, Harel, Parkinson, John S, Vaknin, Ady

“…Motile bacteria use large receptor arrays to detect and follow chemical gradients in their environment. Extended receptor arrays, composed of networked…”
Get full text

Crosstalk between the serine/threonine kinase StkP and the response regulator ComE controls the stress response and intracellular survival of Streptococcus pneumoniae by Piñas, Germán E, Reinoso-Vizcaino, Nicolás M, Yandar Barahona, Nubia Y, Cortes, Paulo R, Duran, Rosario, Badapanda, Chandan, Rathore, Ankita, Bichara, Dario R, Cian, Melina B, Olivero, Nadia B, Perez, Daniel R, Echenique, José

“…Streptococcus pneumoniae is an opportunistic human bacterial pathogen that usually colonizes the upper respiratory tract, but the invasion and survival…”
Get full text

Compensatory evolution of pbp mutations restores the fitness cost imposed by β-lactam resistance in Streptococcus pneumoniae by Albarracín Orio, Andrea G, Piñas, Germán E, Cortes, Paulo R, Cian, Melina B, Echenique, José

“…The prevalence of antibiotic resistance genes in pathogenic bacteria is a major challenge to treating many infectious diseases. The spread of these genes is…”
Get full text

A new serotype 14 variant of the pneumococcal Spain9V-3 international clone detected in the central region of Argentina by Albarracin Orio, Andrea G, Cortes, Paulo R, Tregnaghi, Miguel, Pinas, German E, Argentinean Network Pneumococcus Study Group, Echenique, Jose R

“…1 Departamento de Bioquimica Clinica-CIBICI (CONICET), Facultad de Ciencias Quimicas, Universidad Nacional de Cordoba, Cordoba, Argentina 2 Centro de…”
Get full text

Noncritical Signaling Role of a Kinase–Receptor Interaction Surface in the Escherichia coli Chemosensory Core Complex by Piñas, Germán E., DeSantis, Michael D., Parkinson, John S.

“…In Escherichia coli chemosensory arrays, transmembrane receptors, a histidine autokinase CheA, and a scaffolding protein CheW interact to form an extended…”
Get full text

Compensatory Evolution of pbp Mutations Restores the Fitness Cost Imposed by [beta]-Lactam Resistance in Streptococcus pneumoniae by Orio, Andrea GAlbarracín, Piñas, Germán E, Cortes, Paulo R, Cian, Melina B, Echenique, José

“…The prevalence of antibiotic resistance genes in pathogenic bacteria is a major challenge to treating many infectious diseases. The spread of these genes is…”
Get full text