Search Results - "Pinard, E"
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Biochemical and behavioural characterization of EMPA, a novel high‐affinity, selective antagonist for the OX 2 receptor
Published in British journal of pharmacology (01-04-2009)“…Background and purpose: The OX 2 receptor is a G‐protein‐coupled receptor that is abundantly found in the tuberomammillary nucleus, an important site for the…”
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Biochemical and behavioural characterization of EMPA, a novel high‐affinity, selective antagonist for the OX2 receptor
Published in British journal of pharmacology (01-04-2009)“…Background and purpose: The OX2 receptor is a G‐protein‐coupled receptor that is abundantly found in the tuberomammillary nucleus, an important site for the…”
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Distribution of bone morphogenetic protein and bone morphogenetic protein receptor transcripts in the rodent nervous system and up-regulation of bone morphogenetic protein receptor type II in hippocampal dentate gyrus in a rat model of global cerebral ischemia
Published in Neuroscience (01-01-2000)“…Bone morphogenetic proteins belong to the transforming growth factor-β superfamily and act through serine/threonine kinase type I and type II receptors such as…”
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CA-169: Une expérience régionale de prévention du diabète de type 2. Résultats préliminaires
Published in Diabetes & metabolism (01-03-2016)“…Introduction En Septembre 2012, l'association Dianéfra 93 a mis en place en Seine-Saint-Denis un programme de prévention (PP) du diabète de type 2. Le but est…”
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Discovery of N-(2-hydroxy-2-aryl-cyclohexyl) substituted spiropiperidines as GlyT1 antagonists with improved pharmacological profile
Published in Bioorganic & medicinal chemistry letters (15-01-2006)“…During SAR exploration of N-(2-aryl-cyclohexyl) substituted spiropiperidine as GlyT1 inhibitors, it was found that introduction of a hydroxy group in position…”
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Spatial and temporal MRI profile of ischemic tissue after the acute stages of a permanent mouse model of stroke
Published in The open neuroimaging journal (01-02-2013)“…To characterize the progression of injured tissue resulting from a permanent focal cerebral ischemia after the acute phase, Magnetic Resonance Imaging (MRI)…”
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Dynamic Cerebral Microcirculatory Changes in Transient Forebrain Ischemia in Rats: Involvement of Type I Nitric Oxide Synthase
Published in Journal of cerebral blood flow and metabolism (01-12-2000)“…The diameter of surface microvessels and the erythrocyte velocity and flux through intraparenchymal capillaries in the parietal cortex were measured during…”
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Passage of spermidine across the blood–brain barrier in short recirculation periods following global cerebral ischemia: effects of mild hyperthermia
Published in Neuroscience research (01-08-2002)“…Transport of a polyamine (PA), spermidine (SPMD) into rat brain at various early postischemic periods was studied. Rats underwent 20 min of four-vessel…”
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Pharmacological characterization of Ro 63-1908 (1-[2-(4-hydroxy-phenoxy)-ethyl]-4-(4-methyl-benzyl)-piperidin-4-ol), a novel subtype-selective N-methyl-D-aspartate antagonist
Published in The Journal of pharmacology and experimental therapeutics (01-09-2002)“…Ro 63-1908, 1-[2-(4-hydroxy-phenoxy)-ethyl]-4-(4-methyl-benzyl)-piperidin-4-ol, is a novel subtype-selective N-methyl-D-aspartate (NMDA) antagonist that has…”
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Inhibition of neuronal (type 1) nitric oxide synthase prevents hyperaemia and hippocampal lesions resulting from kainate-induced seizures
Published in Neuroscience (1998)“…The possible roles for nitric oxide produced by neurons in epileptic conditions have been investigated from two different aspects: microcirculation and delayed…”
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Asymmetric Synthesis of the Diterpenoid Marine Toxin (+)-Acetoxycrenulide
Published in Journal of the American Chemical Society (14-02-1996)“…An enantioselective route to the marine toxin (+)-acetoxycrenulide is described. The early stages of the synthesis feature the conversion of (R)-citronellol…”
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Structural insights into mechanism of glycine reuptake inhibition
Published in Acta crystallographica. Section A, Foundations and advances (23-08-2022)“…Abstract only…”
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Effect of MK-801 on Focal Brain Infarction in Normotensive and Hypertensive Rats
Published in Hypertension (Dallas, Tex. 1979) (01-01-1992)“…The effects of the noncompetitive N-methyl-D-aspartate antagonist MK-801 on infarct size and systemic variables after middle cerebral artery occlusion in…”
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Effect of stimulation of the sphenopalatine ganglion on cortical blood flow in the rat
Published in Journal of cerebral blood flow and metabolism (01-12-1988)“…The effects of electrical stimulation of the sphenopalatine ganglion on cortical blood flow and gas partial pressures (PO2 and PCO2) were studied in the…”
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The acute effects of MK-801 on cerebral blood flow and tissue partial pressures of oxygen and carbon dioxide in conscious and alpha-chloralose anaesthetized rats
Published in Neuroscience (1992)“…The dynamic effects of the non-competitive N-methyl-D-aspartate receptor antagonist, MK-801 [(+)-5-methyl-10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5,10-imine]…”
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Blood flow compensates oxygen demand in the vulnerable CA3 region of the hippocampus during kainate-induced seizures
Published in Neuroscience (01-12-1984)“…Local blood flow, and partial pressures of oxygen and carbon dioxide were directly monitored in the vulnerable region of Ammon's horn (e.g. CA3) of…”
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Monoxyde d'azote et régulation de la circulation cérébrale
Published in Archives de pédiatrie (Paris) (1996)Get full text
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Long-Term in Vivo Investigation of Mouse Cerebral Microcirculation by Fluorescence Confocal Microscopy in the Area of Focal Ischemia
Published in Journal of cerebral blood flow and metabolism (01-07-2005)“…This study was designed to assess that mouse pial and cortical microcirculation can be monitored in the long term directly in the area of focal ischemia, using…”
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