Search Results - "Pinarbasi, Emile"
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Glia in FTLD-GRN: from supporting cast to leading role
Published in The Journal of clinical investigation (15-03-2023)“…A subset of the neurodegenerative disease frontotemporal lobar degeneration (FTLD) is caused by mutations in the progranulin (GRN) gene. In this issue of the…”
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Active nuclear import and passive nuclear export are the primary determinants of TDP-43 localization
Published in Scientific reports (04-05-2018)“…ALS (Amyotrophic Lateral Sclerosis) is a neurodegenerative disease characterized by the redistribution of the RNA binding protein TDP-43 in affected neurons:…”
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Neuroimaging features of diffuse hemispheric glioma, H3 G34‐mutant: A case series and systematic review
Published in Journal of neuroimaging (01-01-2022)“…Background and Purpose Diffuse hemispheric gliomas, H3 G34‐mutant (DHGs‐G34m), are newly recognized malignant brain tumors characterized by histone gene…”
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Neuroimaging features of angiocentric glioma: A case series and systematic review
Published in Journal of neuroimaging (01-05-2022)“…Background and Purpose Angiocentric gliomas (AGs) are epileptogenic low‐grade gliomas in young patients. We aimed to investigate the MRI findings of AGs and…”
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Neuroradiological features of the polymorphous low-grade neuroepithelial tumor of the young: five new cases with a systematic review of the literature
Published in Neuroradiology (01-06-2022)“…Purpose Polymorphous low-grade neuroepithelial tumors of the young (PLNTY) is a newly recognized brain tumor with genetic abnormalities frequently involving…”
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Pathogenic Signal Sequence Mutations in Progranulin Disrupt SRP Interactions Required for mRNA Stability
Published in Cell reports (Cambridge) (05-06-2018)“…Cells have evolved quality control pathways to prevent the accumulation of improperly localized proteins, which are often toxic. One of these pathways,…”
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Donor-containing cortical and intraventricular glioneuronal nodules in Huntington’s disease brain decades after fetal cell transplantation
Published in Acta neuropathologica (01-06-2021)Get full text
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Genetically mediated Nf1 loss in mice promotes diverse radiation-induced tumors modeling second malignant neoplasms
Published in Cancer research (Chicago, Ill.) (15-12-2012)“…Second malignant neoplasms (SMN) are therapy-induced malignancies and a growing problem in cancer survivors, particularly survivors of childhood cancers. The…”
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The Evolving Molecular Landscape of High-Grade Gliomas
Published in The cancer journal (Sudbury, Mass.) (01-09-2021)“…Abstract The classification, diagnosis, and biological understanding of high-grade gliomas has been transformed by an evolving understanding of glioma biology…”
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Glia in FTLD-CRN: from supporting cast to leading role
Published in The Journal of clinical investigation (15-03-2023)“…A subset of the neurodegenerative disease frontotemporal lobar degeneration (FTLD) is caused by mutations in the progranulin (GRN) gene. In this issue of the…”
Get full text
Journal Article -
11
Glia in FTLD-GRN: from supporting cast to leading role
Published in The Journal of clinical investigation (01-03-2023)“…A subset of the neurodegenerative disease frontotemporal lobar degeneration (FTLD) is caused by mutations in the progranulin (CRN) gene. In this issue of the…”
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Major Changes in 2021 World Health Organization Classification of Central Nervous System Tumors
Published in Radiographics (01-09-2022)Get full text
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Neuroimaging Features of Cytokine-related Diseases
Published in Radiographics (01-06-2024)“…Cytokines are small secreted proteins that have specific effects on cellular interactions and are crucial for functioning of the immune system. Cytokines are…”
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Dose-Dependent Effects of Focal Fractionated Irradiation on Secondary Malignant Neoplasms in Nf1 Mutant Mice
Published in Cancer research (Chicago, Ill.) (2011)“…Secondary malignant neoplasms (SMN) are increasingly common complications of cancer therapy that have proven difficult to model in mice. Clinical observations…”
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Abstract 3427A: Focal fractionated irradiation induces specific malignancies in a dose-dependent manner in Nf1 mutant mice
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Abstract Purpose: Secondary malignant neoplasms (SMNs) are a severe late complication of radiotherapy (RT). However little is known regarding the influence of…”
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