Search Results - "Pin, Serge"
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Protein–Nanoparticle Interactions: What Are the Protein–Corona Thickness and Organization?
Published in Langmuir (20-08-2019)“…Protein adsorption on a surface is generally evaluated in terms of the evolution of the proteins’ structures and functions. However, when the surface is that…”
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Structural determinants for protein adsorption/non-adsorption to silica surface
Published in PloS one (25-11-2013)“…The understanding of the mechanisms involved in the interaction of proteins with inorganic surfaces is of major interest in both fundamental research and…”
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3
From soil to cacao bean: Unravelling the pathways of cadmium translocation in a high Cd accumulating cultivar of Theobroma cacao L
Published in Frontiers in plant science (02-12-2022)“…The research on strategies to reduce cadmium (Cd) accumulation in cacao beans is currently limited by a lack of understanding of the Cd transfer pathways…”
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The Impact of Virgin and Aged Microstructured Plastics on Proteins: The Case of Hemoglobin Adsorption and Oxygenation
Published in International journal of molecular sciences (27-06-2024)“…Plastic particles, particularly micro- and nanoparticles, are emerging pollutants due to the ever-growing amount of plastics produced across a wide variety of…”
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5
Mercury(II) Binding to Metallothionein in Mytilus edulis revealed by High Energy‐Resolution XANES Spectroscopy
Published in Chemistry : a European journal (18-01-2019)“…Of all divalent metals, mercury (HgII) has the highest affinity for metallothioneins. HgII is considered to be enclosed in the α and β domains as tetrahedral…”
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A proteome scale study reveals how plastic surfaces and agitation promote protein aggregation
Published in Scientific reports (21-01-2023)“…Protein aggregation in biotherapeutics can reduce their activity and effectiveness. It may also promote immune reactions responsible for severe adverse…”
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How Nanoparticles Modify Adsorbed Proteins: Impact of Silica Nanoparticles on the Hemoglobin Active Site
Published in International journal of molecular sciences (01-02-2023)“…The adsorption of proteins on surfaces has been studied for a long time, but the relationship between the structural and functional properties of the adsorbed…”
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8
Human Serum Albumin in the Presence of AGuIX Nanoagents: Structure Stabilisation without Direct Interaction
Published in International journal of molecular sciences (30-06-2020)“…The gadolinium-based nanoagent named AGuIX is a unique radiosensitizer and contrast agent which improves the performance of radiotherapy and medical imaging…”
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Protein Corona Composition of Silica Nanoparticles in Complex Media: Nanoparticle Size does not Matter
Published in Nanomaterials (Basel, Switzerland) (29-01-2020)“…Biomolecules, and particularly proteins, bind on nanoparticle (NP) surfaces to form the so-called protein corona. It is accepted that the corona drives the…”
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10
Myoglobin on Silica: A Case Study of the Impact of Adsorption on Protein Structure and Dynamics
Published in Langmuir (05-11-2013)“…If protein structure and function changes upon adsorption are well documented, modification of adsorbed protein dynamics remains a blind spot, despite its…”
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Manipulating hemoglobin oxygenation using silica nanoparticles: a novel prospect for artificial oxygen carriers
Published in Blood advances (23-01-2018)“…Recently, nanoparticles have attracted much attention as new scaffolds for hemoglobin-based oxygen carriers (HBOCs). Indeed, the development of…”
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12
In Situ Electron-Beam Polymerization Stabilized Quantum Dot Micelles
Published in Langmuir (19-04-2011)“…A polymerizable amphiphile polymer containing PEG was synthesized and used to encapsulate quantum dots in micelles. The quantum dot micelles were then…”
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13
Radiolysis of Confined Water: Production and Reactivity of Hydroxyl Radicals
Published in Angewandte Chemie International Edition (17-12-2004)“…The effect of pore size on the radiolytic production of hydroxyl radicals has been investigated in silica controlled pore glasses (CPGs) by means of the…”
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14
Determination of hydroxyl rate constants by a high-throughput fluorimetric assay: towards a unified reactivity scale for antioxidants
Published in Analyst (London) (01-02-2009)“…We describe in this article the development of a new method for the determination of rate constants of reaction of the hydroxyl radical, generated by…”
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Exploring the Interaction of Human α-Synuclein with Polyethylene Nanoplastics: Insights from Computational Modeling and Experimental Corroboration
Published in Biomacromolecules (23-10-2024)“…Plastics, particularly microplastics (MPs) and nanoplastics (NP), have become major environmental and health concerns due to their high chemical stability. The…”
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16
In Situ Analysis of Weakly Bound Proteins Reveals Molecular Basis of Soft Corona Formation
Published in ACS nano (28-07-2020)“…Few experimental techniques allow the analysis of the protein corona in situ. As a result, little is known on the effects of nanoparticles on weakly bound…”
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Radiation‐Responsive Benzothiazolines as Potential Cleavable Fluorogenic Linkers for Drug Delivery
Published in Chemistry : a European journal (02-06-2023)“…Radiosensitive compounds can be useful for the detection of radiations and also as prodrugs that can be activated during a radiotherapy. Herein we describe the…”
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From Protein Corona to Colloidal Self-Assembly: The Importance of Protein Size in Protein–Nanoparticle Interactions
Published in Langmuir (21-07-2020)“…Protein adsorption on nanoparticles is an important field of study, particularly with regard to nanomedicine and nanotoxicology. Many factors can influence the…”
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Structure and Function of Adsorbed Hemoglobin on Silica Nanoparticles: Relationship between the Adsorption Process and the Oxygen Binding Properties
Published in Langmuir (04-04-2017)“…The connection between the mechanisms of protein adsorption on nanoparticles and the structural and functional properties of the adsorbed protein often remains…”
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Dual Fractions Proteomic Analysis of Silica Nanoparticle Interactions with Protein Extracts
Published in Materials (07-10-2024)“…Dual-fraction proteomics reveals a novel class of proteins impacted by nanoparticle exposure. Nanoparticles (NPs) interact with cellular proteomes, altering…”
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