Search Results - "Pin, Jean‐Jacques"

Impact of Host Immune Status on Discordant Anti-SARS-CoV-2 Circulating B Cell Frequencies and Antibody Levels by Coutant, Frédéric, Pin, Jean-Jacques, Morfin-Sherpa, Florence, Ferry, Tristan, Paul, Stéphane, Pozzetto, Bruno, Normand, Myriam, Miossec, Pierre

“…Individuals with pre-existing chronic systemic low-grade inflammation are prone to develop severe COVID-19 and stronger anti-SARS-CoV-2 antibody responses…”
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Extensive Phenotype of Human Inflammatory Monocyte-Derived Dendritic Cells by Coutant, Frédéric, Pin, Jean-Jacques, Miossec, Pierre

“…Inflammatory monocyte-derived dendritic cells (Mo-DCs) have been described in several chronic inflammatory disorders, such as rheumatoid arthritis (RA), and…”
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Neutralizing and enhancing monoclonal antibodies in SARS-CoV-2 convalescent patients: lessons from early variant infection and impact on shaping emerging variants by Coutant, Frédéric, Touret, Franck, Pin, Jean-Jacques, Alonzo, Marina, Baronti, Cécile, Munier, Sandie, Attia, Mikaël, de Lamballerie, Xavier, Ferry, Tristan, Miossec, Pierre

“…Serological studies of COVID-19 convalescent patients have identified polyclonal lineage-specific and cross-reactive antibodies (Abs), with varying effector…”
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Bispecific antibodies tethering innate receptors induce human tolerant-dendritic cells and regulatory T cells by Lamendour, Lucille, Gilotin, Mäelle, Deluce-Kakwata Nkor, Nora, Lakhrif, Zineb, Meley, Daniel, Poupon, Anne, Laboute, Thibaut, di Tommaso, Anne, Pin, Jean-Jacques, Mulleman, Denis, Le Mélédo, Guillaume, Aubrey, Nicolas, Watier, Hervé, Velge-Roussel, Florence

“…There is an urgent need for alternative therapies targeting human dendritic cells (DCs) that could reverse inflammatory syndromes in many autoimmune and…”
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Mouse Strain Differences in Plasmacytoid Dendritic Cell Frequency and Function Revealed by a Novel Monoclonal Antibody by Asselin-Paturel, Carine, Brizard, Geraldine, Pin, Jean-Jacques, Briere, Francine, Trinchieri, Giorgio

“…We report in this study the generation of a novel rat mAb that recognizes mouse plasmacytoid dendritic cells (pDC). This Ab, named 120G8, stains a small subset…”
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Dendritic Cell Infiltration and Prognosis of Early Stage Breast Cancer by TREILLEUX, Isabelle, BLAY, Jean-Yves, LEBECQUE, Serge, BENDRISS-VERMARE, Nathalie, RAY-COQUARD, Isabelle, BACHELOT, Thomas, GUASTALLA, Jean-Paul, BREMOND, Alain, GODDARD, Sophie, PIN, Jean-Jacques, BARTHELEMY-DUBOIS, Clarisse

“…Purpose: Although dendritic cells (DC) and T cells can infiltrate primary breast carcinoma, it remains unclear whether the immune response influences the…”
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Cleaved/associated TLR3 represents the primary form of the signaling receptor by Toscano, Florent, Estornes, Yann, Virard, François, Garcia-Cattaneo, Alejandra, Pierrot, Audrey, Vanbervliet, Béatrice, Bonnin, Marc, Ciancanelli, Michael J, Zhang, Shen-Ying, Funami, Kenji, Seya, Tsukasa, Matsumoto, Misako, Pin, Jean-Jacques, Casanova, Jean-Laurent, Renno, Toufic, Lebecque, Serge

“…TLR3 belongs to the family of intracellular TLRs that recognize nucleic acids. Endolysosomal localization and cleavage of intracellular TLRs play pivotal roles…”
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The neutralizing and targeting properties of a new set of α4β7-specific antibodies are influenced by their isotype by Girard, Alexandre, Jelicic, Katija, Van Ryk, Don, Rochereau, Nicolas, Cicala, Claudia, Arthos, James, Genin, Christian, Verrier, Bernard, Laurant, Stephanie, Razanajaoana-Doll, Diane, Jean-Jacques, Pin, Paul, Stéphane

“…ABSTRACTThe homing of lymphocytes to mucosa is mainly controlled by α4β7 integrin, and it is amplified during gut chronic inflammation, as occurs with HIV…”
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Evaluation of the Performance of an Indirect Immunofluorescence Assay for the Detection of Anti-MDA5 Antibodies by Nombel, Anaïs, Pin, Jean-Jacques, Fabien, Nicole, Miossec, Pierre, Coutant, Frédéric

“…Anti-melanoma differentiation-associated protein 5 (MDA5) antibody (Ab) positive dermatomyositis (anti-MDA5 DM) is a rare systemic autoimmune disease; further,…”
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The monoclonal antibody DCGM4 recognizes Langerin, a protein specific of Langerhans cells, and is rapidly internalized from the cell surface by Valladeau, Jenny, Duvert‐Frances, Valérie, Pin, Jean‐Jacques, Dezutter‐Dambuyant, Colette, Vincent, Claude, Massacrier, Catherine, Vincent, Jérôme, Yoneda, Kozo, Banchereau, Jacques, Caux, Christophe, Davoust, Jean, Saeland, Sem

“…We generated monoclonal antibody (mAb) DCGM4 by immunization with human dendritic cells (DC) from CD34+ progenitors cultured with granulocyte‐macrophage…”
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Prognostic value of the expression of C-Chemokine Receptor 6 and 7 and their ligands in non-metastatic breast cancer by Cassier, Philippe A, Treilleux, Isabelle, Bachelot, Thomas, Ray-Coquard, Isabelle, Bendriss-Vermare, Nathalie, Ménétrier-Caux, Christine, Trédan, Olivier, Goddard-Léon, Sophie, Pin, Jean-Jacques, Mignotte, Hervé, Bathélémy-Dubois, Clarisse, Caux, Christophe, Lebecque, Serge, Blay, Jean-Yves

“…Chemokines and chemokine receptors are major actors of leukocytes trafficking and some have been shown to play an important role in cancer metastasis…”
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APCs Express DCIR, a Novel C-Type Lectin Surface Receptor Containing an Immunoreceptor Tyrosine-Based Inhibitory Motif by Bates, Elizabeth E. M, Fournier, Nathalie, Garcia, Eric, Valladeau, Jenny, Durand, Isabelle, Pin, Jean-Jacques, Zurawski, Sandra M, Patel, Sejal, Abrams, John S, Lebecque, Serge, Garrone, Pierre, Saeland, Sem

“…We have identified a novel member of the calcium-dependent (C-type) lectin family. This molecule, designated DCIR (for dendritic cell (DC) immunoreceptor), is…”
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CD208/Dendritic Cell-Lysosomal Associated Membrane Protein Is a Marker of Normal and Transformed Type II Pneumocytes by Salaun, Bruno, de Saint-Vis, Blandine, Pacheco, Nathalie, Pacheco, Yves, Riesler, Arnaud, Isaac, Sylvie, Leroux, Caroline, Clair-Moninot, Valérie, Pin, Jean-Jacques, Griffith, Janice, Treilleux, Isabelle, Goddard, Sophie, Davoust, Jean, Kleijmeer, Monique, Lebecque, Serge

“…Dendritic cell-lysosomal associated membrane protein (DC-LAMP)/CD208, a member of the lysosomal associated membrane protein (LAMP) family, is specifically…”
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Fine Mapping the Interaction Between Dendritic Cell-Specific Intercellular Adhesion Molecule (ICAM)-3-Grabbing Nonintegrin and the Cytomegalovirus Envelope Glycoprotein B by Chéneau, Coraline, Coulon, Flora, Porkolab, Vanessa, Fieschi, Franck, Laurant, Stéphanie, Razanajaona-Doll, Diane, Pin, Jean-Jacques, Borst, Eva Maria, Messerle, Martin, Bressollette-Bodin, Céline, Halary, Franck

“…Human cytomegalovirus (HCMV) is a leading cause of virally induced congenital disorders and morbidities in immunocompromised individuals, ie, transplant,…”
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FDF03, a Novel Inhibitory Receptor of the Immunoglobulin Superfamily, Is Expressed by Human Dendritic and Myeloid Cells by Fournier, Nathalie, Chalus, Lionel, Durand, Isabelle, Garcia, Eric, Pin, Jean-Jacques, Churakova, Tatyana, Patel, Segal, Zlot, Constance, Gorman, Dan, Zurawski, Sandra, Abrams, John, Bates, Elizabeth E. M, Garrone, Pierre

“…In this study, we describe human FDF03, a novel member of the Ig superfamily expressed as a monomeric 44-kDa transmembrane glycoprotein and containing a single…”
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A high mucosal blocking score is associated with HIV protection by Girard, Alexandre, Rallón, Norma, Benito, José M, Jospin, Fabienne, Rodriguez, Carmen, Chanut, Blandine, Benjelloun, Fahd, Del Romero, Jorge, Verrier, Bernard, Lucht, Frédéric, Pin, Jean-Jacques, Genin, Christian, Biasin, Mara, Clerici, Mario, Paul, Stéphane

“…BACKGROUND:Early steps of HIV infection are mediated by the binding of the envelope to mucosal receptors as α4β7 and the C-type lectins DC-SIGN and langerin…”
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Cloning and characterization of the mouse homologue of the human dendritic cell maturation marker CD208/DC‐LAMP by Salaun, Bruno, de Saint‐Vis, Blandine, Clair‐Moninot, Valérie, Pin, Jean‐Jacques, Barthélemy‐Dubois, Clarisse, Kissenpfennig, Adrien, Peronne, Catherine, Bates, Elizabeth, Mattei, Marie‐Geneviève, Lebecque, Serge

“…DC‐LAMP, a member of the lysosomal‐associated membrane protein (LAMP) family, is specifically expressed by human dendritic cells (DC) upon activation and…”
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Phenotypic localization of distinct DC subsets in mouse Peyer Patch by Rochereau, Nicolas, Verrier, Bernard, Pin, Jean-Jacques, Genin, Christian, Paul, Stéphane

“…Abstract Peyer's patch have been extensively studied as a major inductive site for mucosal immunity within the small intestine. The intestinal mucosa contains…”
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Macrophage Inflammatory Protein 3α Is Expressed at Inflamed Epithelial Surfaces and Is the Most Potent Chemokine Known in Attracting Langerhans Cell Precursors by Dieu-Nosjean, Marie-Caroline, Massacrier, Catherine, Homey, Bernhard, Vanbervliet, Béatrice, Pin, Jean-Jacques, Vicari, Alain, Lebecque, Serge, Dezutter-Dambuyant, Colette, Schmitt, Daniel, Zlotnik, Albert, Caux, Christophe

“…Dendritic cells (DCs) form a network comprising different populations that initiate and differentially regulate immune responses. Langerhans cells (LCs)…”
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Characterization of a novel canine T-cell line established from a spontaneously occurring aggressive T-cell lymphoma with large granular cell morphology by Bonnefont-Rebeix, Catherine, Fournel-Fleury, Corinne, Ponce, Frédérique, Belluco, Sara, Watrelot, Dorothée, Bouteille, Sylvie E, Rapiteau, Sylvie, Razanajaona-Doll, Diane, Pin, Jean-Jacques, Leroux, Caroline, Marchal, Thierry

“…Abstract Dogs with lymphoma are established as good model for human non-Hodgkin lymphoma studies. Canine cell lines derived from lymphomas may be valuable…”
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