Search Results - "Pilote, S"

METABOLIC SYNDROME ALTERS THE CYP450-MEDIATED METABOLISM OF ARACHIDONIC ACID TOWARDS THE DELETERIOUS VASOCONSTRICTIVE SIDE IN HUMANS by Pilote, S, Drolet, B, Simard, C

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Evaluation of Hepatic CYP2C and CYP2E Expression and Activity in Guinea Pig Models of Diet-Induced Metabolic Syndrome by Patoine, D, Pilote, S, Mercier, P, Drolet, B, Simard, C

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469 Fingolimod (Gilenya®), a New Oral Treatment for Relapsing Forms of Multiple Sclerosis, Causes Bradycardia and Prolongs the QTC Interval by Pilote, S, Patoine, D, Simard, C, Drolet, B

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384 Liver Fatty Infiltration Correlates With Decreased CYP3A Activity in a Diet-Induced Guinea Pig Model of Metabolic Syndrome by Patoine, D, Pilote, S, Drolet, B, Simard, C

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261 Iloperidone (fanapt), a novel atypical antipsychotic, is a potent HERG blocker and delays cardiac ventricular repolarization at clinically relevant concentration by Vigneault, P, Pilote, S, Patoine, D, Simard, C, Drolet, B

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Role of arginine residues on the S4 segment of the Bacillus halodurans Na+ channel in voltage-sensing by Chahine, M, Pilote, S, Pouliot, V, Takami, H, Sato, C

“…The one-domain voltage-gated sodium channel of Bacillus halodurans (NaChBac) is composed of six transmembrane segments (S1-S6) comprising a pore-forming region…”
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Of logos and men: semantic memory impairment for unique entities in a case of semantic variant of primary progressive aphasia by Macoir, J., Pilote-Paradis, S., Lacoste, L., Proulx, M., Auclair-Ouellet, N.

“…In this study, an individual (NG) with the semantic varient of primary progressive aphasis (svPPA) was assessed with tasks designed to investigate the…”
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REMDESIVIR (VEKLURY) FOR TREATING COVID-19 PATIENTS: WHAT TO EXPECT FROM A CARDIAC ELECTROPHYSIOLOGICAL PERSPECTIVE by Pilote, S, Simard, C, Drolet, B

“…Remdesivir was authorized with conditions in Canada on July 27, 2020 for the treatment of severe COVID-19 in adults and youth (aged ≥ 12 years) with pneumonia…”
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ELECLAZINE: THE HIDDEN ANTIDIABETIC POTENTIAL? by Porlier, A., Pilote, S., Simard, C., Drolet, B.

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ELECLAZINE: THE HIDDEN ANTIDIABETIC POTENTIAL? by Porlier, A., Pilote, S., Simard, C., Drolet, B.

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THE SCN5A VARIANT C683R RESULTS IN A GAIN-OF-FUNCTION OF THE CARDIAC SODIUM CURRENT (NAV1.5) WITH ADRENERGIC MODULATION by Steinberg, C., Pilote, S., Simard, C., Drolet, B.

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Classic antihistamines inhibit metoprololhydroxylation in vitro by Hamelin, B., Pilote, S., Turgeon, J.

“…Clinical Pharmacology & Therapeutics (1999) 65, 157–157; doi:…”
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Metoprolol/diphenhydramine interaction in men with high and low CYP2D6 activity by Hamelin, B.A., Méthot, J., Pilote, S., Poirier, P., Dumesnil, J., Turgeon, J.

“…Clinical Pharmacology & Therapeutics (1999) 65, 157–157; doi:…”
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C74 ADVANCES IN TRANSLATIONAL COPD: Effects Of A Pparã And Lxr Agonists Combination Therapy On The Pulmonary Response To Cigarette Smoke by Jubinville, E, Maranda-Robitaille, M, Talbot, M, Thibault, C, Page, M, Beaulieu, M-J, Pilote, S, Aubin, S, Pare, M-E, Drolet, B, Simard, C, Morissette, M C

“…Hypothesis: Concomitant pharmacological activation of PPARy and LXR receptors will promote pulmonary lipid export in response to cigarette smoke, reducing the…”
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Inhibitory effects of MK‐886 on arachidonic acid metabolism in human phagocytes by Ménard, Luc, Pilote, Sylvie, Naccache, Paul H., Laviolette, Michel, Borgeat, Pierre

“…1 We have investigated the inhibitory activity of compound MK‐886 (formerly L‐663,536), an indole derivative, on 5‐lipoxygenase product synthesis in various…”
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Tizanidine (Zanaflex): a muscle relaxant that may prolong the QT interval by blocking IKr by Kaddar, Nisrin, Vigneault, Patrick, Pilote, Sylvie, Patoine, Dany, Simard, Chantale, Drolet, Benoit

“…Tizanidine (Zanaflex) is a centrally acting imidazoline muscle relaxant that is structurally similar to clonidine (α(2)-adrenergic agonist) but not to other…”
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Elevated levels of polyamines and trypanothione resulting from overexpression of the ornithine decarboxylase gene in arsenite‐resistant Leishmania by Haimeur, Anass, Guimond, Chantal, Pilote, Sylvie, Mukhopadhyay, Rita, Rosen, Barry P., Poulin, Richard, Ouellette, Marc

“…The levels of trypanothione, a glutathione–spermidine conjugate, are increased in the protozoan parasite Leishmania selected for resistance to the heavy metal…”
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A convenient five‐drug cocktail for the assessment of major drug metabolizing enzymes: a pilot study by Sharma, Ashish, Pilote, Sylvie, Bélanger, Pierre M., Arsenault, Marie, Hamelin, Bettina A.

“…Aims To assess the feasibility of administering at the same time low doses of five probe drugs, metoprolol (25 mg), chlorzoxazone (250 mg), tolbutamide (250…”
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Modulation of metoprolol pharmacokinetics and hemodynamics by diphenhydramine coadministration during exercise testing in healthy premenopausal women by Sharma, Ashish, Pibarot, Philippe, Pilote, Sylvie, Dumesnil, Jean G, Arsenault, Marie, Bélanger, Pierre Maxime, Meibohm, Bernd, Hamelin, Bettina A

“…Premenopausal women may be most vulnerable to acute coronary syndromes at a point in their menstrual cycle when their plasma estrogen levels are the lowest…”
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Influence of the menstrual cycle on the timing of acute coronary events in premenopausal women by Hamelin, Bettina A, Méthot, Julie, Arsenault, Marie, Pilote, Sylvie, Poirier, Paul, Plante, Sylvain, Bogaty, Peter

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