Search Results - "Pilo, Maria"
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Recent Advances in the Analysis of Phenolic Compounds in Unifloral Honeys
Published in Molecules (08-04-2016)“…Honey is one of the most renowned natural foods. Its composition is extremely variable, depending on its botanical and geographical origins, and the abundant…”
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Rollover Cyclometalation as a Valuable Tool for Regioselective C-H Bond Activation and Functionalization
Published in Molecules (Basel, Switzerland) (10-01-2021)“…Rollover cyclometalation constitutes a particular case of cyclometallation reaction. This reaction occurs when a chelated heterocyclic ligand loses its…”
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3
Sprinkler irrigation in the production of safe rice by soils heavily polluted by arsenic and cadmium
Published in Chemosphere (Oxford) (01-08-2021)“…Among the factors affecting the bioaccumulation of As and Cd in rice, a key role is played by the irrigation methods. The sprinkler irrigation (SP), optimized…”
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Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans
Published in Gut (01-01-2020)“…Increased de novo fatty acid (FA) synthesis and cholesterol biosynthesis have been independently described in many tumour types, including hepatocellular…”
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Tankyrase inhibitors suppress hepatocellular carcinoma cell growth via modulating the Hippo cascade
Published in PloS one (06-09-2017)“…Previous data indicate that Tankyrase inhibitors exert anti-growth functions in many cancer cell lines due to their ability to inactivate the YAP…”
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Multi-Elemental Analysis as a Tool to Ascertain the Safety and the Origin of Beehive Products: Development, Validation, and Application of an ICP-MS Method on Four Unifloral Honeys Produced in Sardinia, Italy
Published in Molecules (Basel, Switzerland) (21-03-2022)“…Despite unifloral honeys from Sardinia, Italy, being appreciated worldwide for their peculiar organoleptic features, their elemental signature has only partly…”
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A functional mammalian target of rapamycin complex 1 signaling is indispensable for c‐Myc‐driven hepatocarcinogenesis
Published in Hepatology (Baltimore, Md.) (01-07-2017)“…Amplification and/or activation of the c‐Myc proto‐oncogene is one of the leading genetic events along hepatocarcinogenesis. The oncogenic potential of c‐Myc…”
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Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice
Published in Scientific reports (09-02-2016)“…Activation of the AKT/mTOR cascade and overexpression of c-Met have been implicated in the development of human hepatocellular carcinoma (HCC). To elucidate…”
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ICP-MS Determination of 23 Elements of Potential Health Concern in Liquids of e-Cigarettes. Method Development, Validation, and Application to 37 Real Samples
Published in Molecules (Basel, Switzerland) (04-11-2021)“…The lack of interest in the determination of toxic elements in liquids for electronic cigarettes (e-liquids) has so far been reflected in the scarce number of…”
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Effect of the irrigation method and genotype on the bioaccumulation of toxic and trace elements in rice
Published in The Science of the total environment (15-12-2020)“…The total concentration of three toxic elements (As, Cd and Pb) and five oligoelements (Cu, Mn, Mo, Ni and Se) has been determined using an original and…”
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Pathogenetic, Prognostic, and Therapeutic Role of Fatty Acid Synthase in Human Hepatocellular Carcinoma
Published in Frontiers in oncology (11-12-2019)“…Hepatocellular carcinoma (HCC) is one of the most common solid tumors worldwide, characterized by clinical aggressiveness, resistance to conventional…”
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Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice
Published in Journal of hepatology (01-12-2017)“…[Display omitted] •A novel mouse model of intrahepatic cholangiocarcinoma (ICC) was established.•Hydrodynamic transfection of activated forms of AKT and Yap…”
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Differential requirement for de novo lipogenesis in cholangiocarcinoma and hepatocellular carcinoma of mice and humans
Published in Hepatology (Baltimore, Md.) (01-06-2016)“…Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) are the most prevalent types of primary liver cancer. These malignancies have limited…”
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Combined CDK4/6 and Pan-mTOR Inhibition Is Synergistic Against Intrahepatic Cholangiocarcinoma
Published in Clinical cancer research (01-01-2019)“…Intrahepatic cholangiocarcinoma (ICC) is an aggressive cancer type, lacking effective therapies and associated with a dismal prognosis. Palbociclib is a…”
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Electrochemical Determination of the “Furanic Index” in Honey
Published in Molecules (Basel, Switzerland) (06-07-2021)“…5-(hydroxymethyl)furan-2-carbaldehyde, better known as hydroxymethylfurfural (HMF), is a well-known freshness parameter of honey: although mostly absent in…”
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Conducting Polymers in Amperometric Sensors: A State of the Art over the Last 15 Years with a Focus on Polypyrrole-, Polythiophene-, and Poly(3,4-ethylenedioxythiophene)-Based Materials
Published in Chemosensors (01-05-2024)“…Conducting polymers are used in a wide range of applications, especially in the design and development of electrochemical sensors. Their main advantage, in…”
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Elemental Fingerprinting of Pecorino Romano and Pecorino Sardo PDO: Characterization, Authentication and Nutritional Value
Published in Molecules (Basel, Switzerland) (16-02-2024)“…Sardinia, located in Italy, is a significant producer of Protected Designation of Origin (PDO) sheep cheeses. In response to the growing demand for…”
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RP-HPLC determination of water-soluble vitamins in honey
Published in Talanta (Oxford) (15-01-2011)“…The assessment and validation of reliable analytical methods for the determination of vitamins in sugar-based matrices (e.g. honey) are still scarcely explored…”
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An Analytical Protocol for the Differentiation and the Potentiometric Determination of Fluorine-Containing Fractions in Bovine Milk
Published in Molecules (Basel, Switzerland) (31-01-2023)“…Free fluoride ions are effective in combating caries in children, and their supplementation in milk has been widely used worldwide for this purpose…”
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Classical vs. Non-Classical Cyclometalated Pt(II) Complexes
Published in Molecules (Basel, Switzerland) (25-10-2022)“…Rollover cyclometalated complexes constitute a family of derivatives which differ from classical cyclometalated species in certain aspects. Various potential…”
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