Search Results - "Pillman, Katherine A"

The RNA Binding Protein Quaking Regulates Formation of circRNAs by Conn, Simon J., Pillman, Katherine A., Toubia, John, Conn, Vanessa M., Salmanidis, Marika, Phillips, Caroline A., Roslan, Suraya, Schreiber, Andreas W., Gregory, Philip A., Goodall, Gregory J.

“…Circular RNAs (circRNAs), formed by non-sequential back-splicing of pre-mRNA transcripts, are a widespread form of non-coding RNA in animal cells. However, it…”
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Naturally existing isoforms of miR-222 have distinct functions by Yu, Feng, Pillman, Katherine A, Neilsen, Corine T, Toubia, John, Lawrence, David M, Tsykin, Anna, Gantier, Michael P, Callen, David F, Goodall, Gregory J, Bracken, Cameron P

“…Deep-sequencing reveals extensive variation in the sequence of endogenously expressed microRNAs (termed 'isomiRs') in human cell lines and tissues, especially…”
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On the rules of engagement for microRNAs targeting protein coding regions by Sapkota, Sunil, Pillman, Katherine A, Dredge, B Kate, Liu, Dawei, Bracken, Julie M, Kachooei, Saba Ataei, Chereda, Bradley, Gregory, Philip A, Bracken, Cameron P, Goodall, Gregory J

“…Abstract MiRNAs post-transcriptionally repress gene expression by binding to mRNA 3′UTRs, but the extent to which they act through protein coding regions (CDS…”
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Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasion by Bracken, Cameron P, Li, Xiaochun, Wright, Josephine A, Lawrence, David M, Pillman, Katherine A, Salmanidis, Marika, Anderson, Matthew A, Dredge, B Kate, Gregory, Philip A, Tsykin, Anna, Neilsen, Corine, Thomson, Daniel W, Bert, Andrew G, Leerberg, Joanne M, Yap, Alpha S, Jensen, Kirk B, Khew-Goodall, Yeesim, Goodall, Gregory J

“…The microRNAs of the miR‐200 family maintain the central characteristics of epithelia and inhibit tumor cell motility and invasiveness. Using the Ago‐HITS‐CLIP…”
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miRNA length variation during macrophage stimulation confounds the interpretation of results: implications for miRNA quantification by RT-qPCR by Pillman, Katherine A, Goodall, Gregory J, Bracken, Cameron P, Gantier, Michael P

“…Most microRNAs (miRNAs) are expressed as a mix of length isoforms (referred to as isomiRs). IsomiR stoichiometry can be differentially impacted upon cell…”
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p53 Represses the Oncogenic Sno-MiR-28 Derived from a SnoRNA by Yu, Feng, Bracken, Cameron P, Pillman, Katherine A, Lawrence, David M, Goodall, Gregory J, Callen, David F, Neilsen, Paul M

“…p53 is a master tumour repressor that participates in vast regulatory networks, including feedback loops involving microRNAs (miRNAs) that regulate p53 and…”
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Post-transcriptional Gene Regulation by MicroRNA-194 Promotes Neuroendocrine Transdifferentiation in Prostate Cancer by Fernandes, Rayzel C., Toubia, John, Townley, Scott, Hanson, Adrienne R., Dredge, B. Kate, Pillman, Katherine A., Bert, Andrew G., Winter, Jean M., Iggo, Richard, Das, Rajdeep, Obinata, Daisuke, Sandhu, Shahneen, Risbridger, Gail P., Taylor, Renea A., Lawrence, Mitchell G., Butler, Lisa M., Zoubeidi, Amina, Gregory, Philip A., Tilley, Wayne D., Hickey, Theresa E., Goodall, Gregory J., Selth, Luke A.

“…Potent therapeutic inhibition of the androgen receptor (AR) in prostate adenocarcinoma can lead to the emergence of neuroendocrine prostate cancer (NEPC), a…”
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miR-222 isoforms are differentially regulated by type-I interferon by Nejad, Charlotte, Pillman, Katherine A, Siddle, Katherine J, Pépin, Geneviève, Änkö, Minna-Liisa, McCoy, Claire E, Beilharz, Traude H, Quintana-Murci, Lluís, Goodall, Gregory J, Bracken, Cameron P, Gantier, Michael P

“…Endogenous microRNAs (miRNAs) often exist as multiple isoforms (known as "isomiRs") with predominant variation around their 3'-end. Increasing evidence…”
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Assessing the gene regulatory properties of Argonaute-bound small RNAs of diverse genomic origin by Thomson, Daniel W, Pillman, Katherine A, Anderson, Matthew L, Lawrence, David M, Toubia, John, Goodall, Gregory J, Bracken, Cameron P

“…High-throughput sequencing reveals an abundance of microRNA-sized fragments derived from larger non-coding RNAs. Roles for these small RNAs in gene silencing…”
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Extensive transcriptional responses are co-ordinated by microRNAs as revealed by Exon-Intron Split Analysis (EISA) by Pillman, Katherine A, Scheer, Kaitlin G, Hackett-Jones, Emily, Saunders, Klay, Bert, Andrew G, Toubia, John, Whitfield, Holly J, Sapkota, Sunil, Sourdin, Laura, Pham, Hoang, Le, Thuc D, Cursons, Joseph, Davis, Melissa J, Gregory, Philip A, Goodall, Gregory J, Bracken, Cameron P

“…Epithelial-mesenchymal transition (EMT) has been a subject of intense scrutiny as it facilitates metastasis and alters drug sensitivity. Although…”
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Identification of an enhancer that increases miR-200b~200a~429 gene expression in breast cancer cells by Attema, Joanne L, Bert, Andrew G, Lim, Yat-Yuen, Kolesnikoff, Natasha, Lawrence, David M, Pillman, Katherine A, Smith, Eric, Drew, Paul A, Khew-Goodall, Yeesim, Shannon, Frances, Goodall, Gregory J

“…The miR-200b~200a~429 gene cluster is a key regulator of EMT and cancer metastasis, however the transcription-based mechanisms controlling its expression…”
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Nuclear export of circular RNA by Ngo, Linh H., Bert, Andrew G., Dredge, B. Kate, Williams, Tobias, Murphy, Vincent, Li, Wanqiu, Hamilton, William B., Carey, Kirstyn T., Toubia, John, Pillman, Katherine A., Liu, Dawei, Desogus, Jessica, Chao, Jeffrey A., Deans, Andrew J., Goodall, Gregory J., Wickramasinghe, Vihandha O.

“…Circular RNAs (circRNAs), which are increasingly being implicated in a variety of functions in normal and cancerous cells 1 – 5 , are formed by back-splicing…”
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miR‐200/375 control epithelial plasticity‐associated alternative splicing by repressing the RNA‐binding protein Quaking by Pillman, Katherine A, Phillips, Caroline A, Roslan, Suraya, Toubia, John, Dredge, B Kate, Bert, Andrew G, Lumb, Rachael, Neumann, Daniel P, Li, Xiaochun, Conn, Simon J, Liu, Dawei, Bracken, Cameron P, Lawrence, David M, Stylianou, Nataly, Schreiber, Andreas W, Tilley, Wayne D, Hollier, Brett G, Khew‐Goodall, Yeesim, Selth, Luke A, Goodall, Gregory J, Gregory, Philip A

“…Members of the miR‐200 family are critical gatekeepers of the epithelial state, restraining expression of pro‐mesenchymal genes that drive…”
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Differentially expressed miRNAs in bone after methotrexate treatment by Zhang, Yali, Liu, Liang, Pillman, Katherine A, Hayball, John, Su, Yu‐Wen, Xian, Cory J.

“…Previous studies have shown that administration of antimetabolite methotrexate (MTX) caused a reduced trabecular bone volume and increased marrow adiposity…”
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Publisher Correction: Nuclear export of circular RNA by Ngo, Linh H., Bert, Andrew G., Dredge, B. Kate, Williams, Tobias, Murphy, Vincent, Li, Wanqiu, Hamilton, William B., Carey, Kirstyn T., Toubia, John, Pillman, Katherine A., Liu, Dawei, Desogus, Jessica, Chao, Jeffrey A., Deans, Andrew J., Goodall, Gregory J., Wickramasinghe, Vihandha O.

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ESRP1 controls biogenesis and function of a large abundant multiexon circRNA by Liu, Dawei, Dredge, B Kate, Bert, Andrew G, Pillman, Katherine A, Toubia, John, Guo, Wenting, Dyakov, Boris J A, Migault, Melodie M, Conn, Vanessa M, Conn, Simon J, Gregory, Philip A, Gingras, Anne-Claude, Patel, Dinshaw, Wu, Baixing, Goodall, Gregory J

“…While the majority of circRNAs are formed from infrequent back-splicing of exons from protein coding genes, some can be produced at quite high level and in a…”
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Insufficiently complex unique-molecular identifiers (UMIs) distort small RNA sequencing by Saunders, Klay, Bert, Andrew G., Dredge, B. Kate, Toubia, John, Gregory, Philip A., Pillman, Katherine A., Goodall, Gregory J., Bracken, Cameron P.

“…The attachment of unique molecular identifiers (UMIs) to RNA molecules prior to PCR amplification and sequencing, makes it possible to amplify libraries to a…”
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Haemolysis Detection in MicroRNA-Seq from Clinical Plasma Samples by Smith, Melanie D, Leemaqz, Shalem Y, Jankovic-Karasoulos, Tanja, McAninch, Dale, McCullough, Dylan, Breen, James, Roberts, Claire T, Pillman, Katherine A

“…The abundance of cell-free microRNA (miRNA) has been measured in blood plasma and proposed as a source of novel, minimally invasive biomarkers for several…”
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The landscape of alternative polyadenylation during EMT and its regulation by the RNA-binding protein Quaking by Neumann, Daniel P, Pillman, Katherine A, Dredge, B Kate, Bert, Andrew G, Phillips, Caroline A, Lumb, Rachael, Ramani, Yesha, Bracken, Cameron P, Hollier, Brett G, Selth, Luke A, Beilharz, Traude H, Goodall, Gregory J, Gregory, Philip A

“…Epithelial-mesenchymal transition (EMT) plays important roles in tumour progression and is orchestrated by dynamic changes in gene expression. While it is well…”
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DraculR: A Web-Based Application for In Silico Haemolysis Detection in High-Throughput microRNA Sequencing Data by Smith, Melanie D, Leemaqz, Shalem Y, Jankovic-Karasoulos, Tanja, McCullough, Dylan, McAninch, Dale, Arthurs, Anya L, Breen, James, Roberts, Claire T, Pillman, Katherine A

“…The search for novel microRNA (miRNA) biomarkers in plasma is hampered by haemolysis, the lysis and subsequent release of red blood cell contents, including…”
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