Search Results - "Pilli, Tania"
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Vemurafenib may overcome TNF-related apoptosis-inducing ligand (TRAIL) resistance in anaplastic thyroid cancer cells
Published in Endocrine (2020)“…Purpose Anaplastic thyroid cancer (ATC) is rare but with poor prognosis. TRAIL can selectively induce apoptosis in cancer cells; however, resistance is quite…”
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Preliminary results from whole-genome expression analysis in patients with secondary adrenal insufficiency treated with modified-release hydrocortisone
Published in Endocrine (01-07-2021)“…Purpose Conventional (CONV) treatment of adrenal insufficiency (AI) is associated with risk of overtreatment: glyco-metabolic impairment, bone loss, and…”
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Permanent diabetes insipidus in a patient with mesothelioma treated with immunotherapy
Published in Archives of Endocrinology and Metabolism (01-08-2020)“…Checkpoint inhibitors have substantially improved the prognosis for patients with advanced malignancy. Treatment with immunomodulants has the ability to…”
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Molecular Signature of Indeterminate Thyroid Lesions: Current Methods to Improve Fine Needle Aspiration Cytology (FNAC) Diagnosis
Published in International journal of molecular sciences (06-04-2017)“…Fine needle aspiration cytology (FNAC) represents the gold standard for determining the nature of thyroid nodules. It is a reliable method with good…”
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A Comparison of 1850 (50 mCi) and 3700 MBq (100 mCi) 131-Iodine Administered Doses for Recombinant Thyrotropin-Stimulated Postoperative Thyroid Remnant Ablation in Differentiated Thyroid Cancer
Published in The journal of clinical endocrinology and metabolism (01-09-2007)“…Objective: Recently, a multicenter study in differentiated thyroid cancer (DTC) patients showed that 3700 MBq 131-iodine (131I) after recombinant human TSH…”
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Risk of Second Malignant Neoplasm in Familial Non-Medullary Thyroid Cancer Patients
Published in Frontiers in endocrinology (Lausanne) (04-03-2022)“…Survival rates in patients with non-medullary thyroid carcinoma (NMTC) are high, increasing the possibility to develop a second malignant neoplasm (SMN). Many…”
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The Combination of Sonographic Features and the Seven-Gene Panel May be Useful in the Management of Thyroid Nodules With Indeterminate Cytology
Published in Frontiers in endocrinology (Lausanne) (24-02-2021)“…The management of patients with indeterminate thyroid nodules, which account for 10-25% of thyroid fine needle aspiration biopsies (FNABs), is still very…”
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Potential utility and limitations of thyroid cancer cell lines as models for studying thyroid cancer
Published in Thyroid (New York, N.Y.) (01-12-2009)“…Tumor-derived cell lines are widely used to study the mechanisms involved in thyroid carcinogenesis but recent studies have reported redundancy among thyroid…”
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EIF1AX c.338-2A>T splice site mutation in a patient with trabecular adenoma and cytological indeterminate lesion
Published in Archives of Endocrinology and Metabolism (01-04-2020)“…The EIF1AX gene mutations have been recently associated with papillary thyroid carcinoma and anaplastic thyroid cancer. According with these reports, the gene…”
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MADD knock-down enhances doxorubicin and TRAIL induced apoptosis in breast cancer cells
Published in PloS one (15-02-2013)“…The Map kinase Activating Death Domain containing protein (MADD) isoform of the IG20 gene is over-expressed in different types of cancer tissues and cell lines…”
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Inhibition of the pro-survival factor MADD (MAP Kinase Activating Death Domain) in human colorectal cancer
Published in Journal of the American College of Surgeons (2011)“…Introduction Colorectal cancer (CRC) is the third leading cause of cancer-related mortality. Up to 50% of CRC patients will develop metastatic disease. For…”
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Long-term Effects of Radioiodine in Toxic Multinodular Goiter: Thyroid Volume, Function, and Autoimmunity
Published in The journal of clinical endocrinology and metabolism (01-07-2020)“…Long-term studies evaluating the treatment of toxic multinodular goiter (TMNG) with fixed activities of radioiodine (RAI) are lacking. The objective of this…”
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Circulating miRNA95 and miRNA190 Are Sensitive Markers for the Differential Diagnosis of Thyroid Nodules in a Caucasian Population
Published in The journal of clinical endocrinology and metabolism (01-11-2014)“…Context: MicroRNA (miRNAs) are nonprotein-encoding RNAs that regulate gene expression and enable the distinction of benign from malignant tissues in human…”
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Role of Age at Diagnosis in Defining Potential Familial Nonmedullary Thyroid Cancer in Kindreds With Two Affected Members
Published in The journal of clinical endocrinology and metabolism (01-02-2021)“…Abstract Context The definition of familial nonmedullary thyroid cancer (FNMTC) in 2 or more first-degree relatives is controversial due to the high…”
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No need of glucocorticoid dose adjustment in patients with adrenal insufficiency before COVID-19 vaccine
Published in European journal of endocrinology (01-07-2022)“…Objective Coronavirus disease-2019 (COVID-19) causes acute respiratory distress syndrome. Patients with adrenal insufficiency (AI) may develop severe…”
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Diagnostic Value of Circulating microRNA-95 and -190 in the Differential Diagnosis of Thyroid Nodules: A Validation Study in 1000 Consecutive Patients
Published in Thyroid (New York, N.Y.) (01-08-2017)“…It has recently been demonstrated that the combination of miRNA-190 and -95 (expressed as probability of malignant risk: pmiRNA) in the serum of Caucasian…”
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Screening of Organ-Specific Autoantibodies in a Large Cohort of Patients with Autoimmune Thyroid Diseases
Published in Thyroid (New York, N.Y.) (01-09-2021)“…Autoimmune diseases tend to cluster in the same individual or in families. Four types of autoimmune polyglandular syndromes (APS) have been described based on…”
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Prospective Validation of ATA and ETA Sonographic Pattern Risk of Thyroid Nodules Selected for FNAC
Published in The journal of clinical endocrinology and metabolism (01-06-2018)“…Recently, the American Thyroid Association (ATA) and the European Thyroid Association (ETA) have proposed that thyroid ultrasound (US) should be used to…”
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Clinical significance of type 2 iodothyronine deiodinase polymorphism
Published in Expert review of endocrinology & metabolism (03-09-2018)“…Biological activity of thyroid hormones (TH) is regulated by enzymes known as deiodinases. The most important is represented by the type 2 deiodinase (D2),…”
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