Search Results - "Pillar, Joann S."

Isolation and Characterization of PDE9A, a Novel Human cGMP-specific Phosphodiesterase by Fisher, D A, Smith, J F, Pillar, J S, St Denis, S H, Cheng, J B

“…We have cloned and characterized the first human isozyme in a new family of cyclic nucleotide phosphodiesterases, PDE9A. By sequence homology in the catalytic…”
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Isolation and Characterization of PDE8A, a Novel Human cAMP-Specific Phosphodiesterase by Fisher, Douglas A., Smith, James F., Pillar, Joann S., St. Denis, Suzanne H., Cheng, John B.

“…As part of our efforts to understand the regulation of intracellular cAMP and to generate new targets for pharmacological intervention, we have cloned and…”
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Biarylcarboxylic Acids and -amides:  Inhibition of Phosphodiesterase Type IV versus [3H]Rolipram Binding Activity and Their Relationship to Emetic Behavior in the Ferret by Duplantier, Allen J, Biggers, Michael S, Chambers, Robert J, Cheng, John B, Cooper, Kelvin, Damon, David B, Eggler, James F, Kraus, Kenneth G, Marfat, Anthony, Masamune, Hiroko, Pillar, Joann S, Shirley, John T, Umland, John P, Watson, John W

“…In addition to having desirable inhibitory effects on inflammation, anaphylaxis, and smooth muscle contraction, PDE-IV inhibitors also produce undesirable side…”
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N-carbamoyl analogs of zafirlukast: Potent receptor antagonists of leukotriene D 4 by Brown, Matthew F., Marfat, Anthony, Antognoli, Gerard, Chambers, Robert J., Cheng, John B., Damon, David B., Liston, Theodore E., McGlynn, Molly A., O'Sullivan, Stacie P., Owens, Brian S., Pillar, Joann S., Shirley, John T., Watson, John W.

“…Exploration of the indole nitrogen region of Zafirlukast ( 1) has uncovered a potent series of cysteinyl leukotriene D 4 (LTD 4) antagonists. These studies…”
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N-carbamoyl analogs of zafirlukast: Potent receptor antagonists of leukotriene D4 by BROWN, M. F, MARFAT, A, PILLAR, J. S, SHIRLEY, J. T, WATSON, J. W, ANTOGNOLI, G, CHAMBERS, R. J, CHENG, J. B, DAMON, D. B, LISTON, T. E, MCGLYNN, M. A, O'SULLIVAN, S. P, OWENS, B. S

“…Exploration of the indole nitrogen region of Zafirlukast (1) has uncovered a potent series of cysteinyl leukotriene D4 (LTD4) antagonists. These studies showed…”
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Vortex flow filtration of mammalian and insect cells by HAWRYLIK, S. J, WASILKO, D. J, PILLAR, J. S, CHENG, J. B, LEE, S. E

“…The use of vortex flow filtration for harvesting cells or conditioned medium from large scale bioreactors has proven to be an efficient, low shear method of…”
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