Search Results - "Pillai, Sneha S."

Detecting early onset of anthracyclines-induced cardiotoxicity using a novel panel of biomarkers in West-Virginian population with breast cancer by Lakhani, Hari Vishal, Pillai, Sneha S., Zehra, Mishghan, Dao, Benjamin, Tirona, Maria Tria, Thompson, Ellen, Sodhi, Komal

“…Cardiotoxic manifestation associated with breast cancer treatment by anthracycline regimen increases patients’ susceptibility to myocardial injury, reduction…”
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Predicting Nonalcoholic Fatty Liver Disease through a Panel of Plasma Biomarkers and MicroRNAs in Female West Virginia Population by Pillai, Sneha S, Lakhani, Hari Vishal, Zehra, Mishghan, Wang, Jiayan, Dilip, Anum, Puri, Nitin, O'Hanlon, Kathleen, Sodhi, Komal

“…(1) Background: Nonalcoholic fatty liver disease (NAFLD) is primarily characterized by the presence of fatty liver, hepatic inflammation and fibrogenesis…”
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Cognitive dysfunction associated with COVID-19: Prognostic role of circulating biomarkers and microRNAs by Alvarez, Marissa, Trent, Erick, Goncalves, Bruno De Souza, Pereira, Duane G., Puri, Raghav, Frazier, Nicolas Anthony, Sodhi, Komal, Pillai, Sneha S.

“…COVID-19 is renowned as a multi-organ disease having subacute and long-term effects with a broad spectrum of clinical manifestations. The evolving scientific…”
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COVID-19-Associated Sepsis: Potential Role of Phytochemicals as Functional Foods and Nutraceuticals by de Souza Goncalves, Bruno, Sangani, Darshan, Nayyar, Aleen, Puri, Raghav, Irtiza, Mahir, Nayyar, Asma, Khalyfa, Abdelnaby, Sodhi, Komal, Pillai, Sneha S

“…The acute manifestations of coronavirus disease 2019 (COVID-19) exhibit the hallmarks of sepsis-associated complications that reflect multiple organ failure…”
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Therapeutic Efficacy of Antioxidants in Ameliorating Obesity Phenotype and Associated Comorbidities by Tun, Steven, Spainhower, Caleb James, Cottrill, Cameron Lee, Lakhani, Hari Vishal, Pillai, Sneha S., Dilip, Anum, Chaudhry, Hibba, Shapiro, Joseph I., Sodhi, Komal

“…Obesity has been a worldwide epidemic for decades. Despite the abundant increase in knowledge regarding the etiology and pathogenesis of obesity, the…”
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Elucidating Potential Profibrotic Mechanisms of Emerging Biomarkers for Early Prognosis of Hepatic Fibrosis by Zehra, Mishghan, Curry, James C, Pillai, Sneha S, Lakhani, Hari Vishal, Edwards, Cory E, Sodhi, Komal

“…Hepatic fibrosis has been associated with a series of pathophysiological processes causing excessive accumulation of extracellular matrix proteins. Several…”
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Biomarker panel for early screening of trastuzumab -induced cardiotoxicity among breast cancer patients in west virginia by Pillai, Sneha S., Pereira, Duane G., Bonsu, Gloria, Chaudhry, Hibba, Puri, Nitin, Lakhani, Hari Vishal, Tirona, Maria Tria, Sodhi, Komal, Thompson, Ellen

“…Cardiotoxicity is a well-known pathophysiological consequence in breast cancer patients receiving trastuzumab. Trastuzumab related cardiotoxicity typically…”
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A Review of miRNAs as Biomarkers and Effect of Dietary Modulation in Obesity Associated Cognitive Decline and Neurodegenerative Disorders by Perdoncin, Maddie, Konrad, Alec, Wyner, Joshua R, Lohana, Samir, Pillai, Sneha S, Pereira, Duane G, Lakhani, Hari Vishal, Sodhi, Komal

“…There has been a progressive increase in the prevalence of obesity and its comorbidities such as type 2 diabetes and cardiovascular diseases worldwide. Recent…”
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Beneficial Role of HO-1-SIRT1 Axis in Attenuating Angiotensin II-Induced Adipocyte Dysfunction by Lakhani, Hari Vishal, Zehra, Mishghan, Pillai, Sneha S, Puri, Nitin, Shapiro, Joseph I, Abraham, Nader G, Sodhi, Komal

“…Angiotensin II (Ang II), released by the renin-angiotensin-aldosterone system (RAAS), contributes to the modulatory role of the RAAS in adipose tissue…”
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Insight into the Inter-Organ Crosstalk and Prognostic Role of Liver-Derived MicroRNAs in Metabolic Disease Progression by Goncalves, Bruno de Souza, Meadows, Avery, Pereira, Duane G, Puri, Raghav, Pillai, Sneha S

“…Dysfunctional hepatic metabolism has been linked to numerous diseases, including non-alcoholic fatty liver disease, the most common chronic liver disorder…”
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Na/K-ATPase suppresses LPS-induced pro-inflammatory signaling through Lyn by Zhang, Jue, Chang, Jackie, Beg, Mirza Ahmar, Huang, Wenxin, Zhao, Yiqiong, Dai, Wen, Wu, Xiaopeng, Cui, Weiguo, Pillai, Sneha S., Lakhani, Hari Vishal, Sodhi, Komal, Shapiro, Joseph I., Sahoo, Daisy, Zheng, Ze, Silverstein, Roy L., Chen, Yiliang

“…Na/K-ATPase (NKA), besides its ion transporter function, is a signal transducer by regulating Src family kinases (SFK). The signaling NKA contributes to…”
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Contribution of adipocyte Na/K-ATPase α1/CD36 signaling induced exosome secretion in response to oxidized LDL by Pillai, Sneha S, Pereira, Duane G, Zhang, Jue, Huang, Wenxin, Beg, Mirza Ahmar, Knaack, Darcy A, de Souza Goncalves, Bruno, Sahoo, Daisy, Silverstein, Roy L, Shapiro, Joseph I, Sodhi, Komal, Chen, Yiliang

“…Adipose tissue constantly secretes adipokines and extracellular vesicles including exosomes to crosstalk with distinct tissues and organs for whole-body…”
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Role of adipocyte Na,K-ATPase oxidant amplification loop in cognitive decline and neurodegeneration by Sodhi, Komal, Pratt, Rebecca, Wang, Xiaoliang, Lakhani, Hari Vishal, Pillai, Sneha S., Zehra, Mishghan, Wang, Jiayan, Grover, Lawrence, Henderson, Brandon, Denvir, James, Liu, Jiang, Pierre, Sandrine, Nelson, Thomas, Shapiro, Joseph I.

“…Recent studies suggest that a western diet may contribute to clinical neurodegeneration and dementia. Adipocyte-specific expression of the Na,K-ATPase…”
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Attenuation of high glucose induced apoptotic and inflammatory signaling pathways in RIN-m5F pancreatic β cell lines by Hibiscus rosa sinensis L. petals and its phytoconstituents by Pillai, Sneha S., Mini, S.

“…Hibiscus rosa sinensis petals possess wide range of pharmacological properties, with remarkable nutritional values. Diabetes is one of the most devastating…”
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Systematic Review of Clinical Insights into Novel Coronavirus (CoVID-19) Pandemic: Persisting Challenges in U.S. Rural Population by Lakhani, Hari Vishal, Pillai, Sneha S, Zehra, Mishghan, Sharma, Ishita, Sodhi, Komal

“…(1) Introduction. A recent viral outbreak of novel coronavirus (CoVID-19) was declared as a pandemic by the World Health Organization (WHO) due to its global…”
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Antagonism of Na,K‐ATPase signaling by pNaKtide can attenuate systemic inflammatory response in murine sepsis model induced by cecal ligation and puncture by Pereira, Duane G., Pillai, Sneha S., Lakhani, Hari Vishal, Wang, Jiayan, Sodhi, Komal

“…Introduction Oxidative stress and associated inflammatory processes are crucial in the development and progression of sepsis, resulting in an immune response…”
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Pivotal role of adipocyte‐Na/K‐ATPase Signaling in the pathogenesis of Experimental Uremic Cardiomyopathy by fat transplantation by Pillai, Sneha S., Lakhani, Hari Vishal, Zehra, Mishghan, Pereira, Duane G., Sodhi, Komal

“…Objective Mounting evidence highlights the role of adipose tissue in the development of systemic inflammation that contributes to various metabolic…”
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Mechanisms in Chronic Kidney Disease and Associated Cardiovascular Remodeling Contributes to the Progression of Cognitive Impairment in Women by Lakhani, Hari Vishal, Thakur, Amrit, Pillai, Sneha S., Pereira, Duane G., Thompson, Ellen, Sodhi, Komal, Fedorova, Olga V.

“…Introduction In end‐stage chronic kidney disease (CKD) (stages 4‐5) the prevalence of cognitive impairment (CI) has been estimated at 30‐60%, twice the values…”
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Mechanistic Insight of Na/K-ATPase Signaling and HO-1 into Models of Obesity and Nonalcoholic Steatohepatitis by Pratt, Rebecca, Lakhani, Hari Vishal, Zehra, Mishghan, Desauguste, Rutmann, Pillai, Sneha S, Sodhi, Komal

“…Obesity is a multifaceted pathophysiological condition that has been associated with lipid accumulation, adipocyte dysfunction, impaired mitochondrial…”
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Polyphenols rich Hibiscus rosa sinensis Linn. petals modulate diabetic stress signalling pathways in streptozotocin-induced experimental diabetic rats by Pillai, Sneha S., Mini, S.

“…•The use of plants in the treatment of diabetes is a well-established practice in traditional medicine.•The effect of Hibiscus rosa sinensis Linn. petals on…”
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