Search Results - "Pillai, Dylan"

The impact of the COVID-19 pandemic on malaria in returning travellers in Canada: a retrospective population-based cohort study by Lieu, Anthony, Mah, Jordan, Desgagnés, Noémie, Pillai, Dylan R

“…In high-income, low-prevalence settings, travel patterns largely govern malaria transmission; the COVID-19 pandemic has led to travel restrictions resulting in…”
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A metagenomic analysis of pandemic influenza A (2009 H1N1) infection in patients from North America by Greninger, Alexander L, Chen, Eunice C, Sittler, Taylor, Scheinerman, Alex, Roubinian, Nareg, Yu, Guixia, Kim, Edward, Pillai, Dylan R, Guyard, Cyril, Mazzulli, Tony, Isa, Pavel, Arias, Carlos F, Hackett, John, Schochetman, Gerald, Miller, Steve, Tang, Patrick, Chiu, Charles Y

“…Although metagenomics has been previously employed for pathogen discovery, its cost and complexity have prevented its use as a practical front-line diagnostic…”
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Prevalence and Epidemiological Characteristics of Asymptomatic Malaria Based on Ultrasensitive Diagnostics: A Cross-sectional Study by Girma, Seble, Cheaveau, James, Mohon, Abu Naser, Marasinghe, Dewdunee, Legese, Ruth, Balasingam, Nirujah, Abera, Adugna, Feleke, Sindew M, Golassa, Lemu, Pillai, Dylan R

“…As the global public-health objectives for malaria evolve from malaria control towards malaria elimination, there is increasing interest in the significance of…”
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Success of Self-Administered Home Fecal Transplantation for Chronic Clostridium difficile Infection by Silverman, Michael S, Davis, Ian, Pillai, Dylan R

“…Background & Aims Clostridium difficile infection (CDI) can relapse in patients with significant comorbidities. A subset of these patients becomes dependent on…”
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Ultrasensitive Reverse Transcriptase Loop-Mediated Isothermal Amplification (US-LAMP)-Based Detection of Malaria Infection from Dried Blood Spots by Mohon, Abu Naser, Toppings, Noah, Castañeda-Mogollón, Daniel, Kamaliddin, Claire, Pillai, Dylan R

“…Submicroscopic malaria diagnosis requires highly sensitive tools instead of the conventional microscopy and rapid diagnostic tests (RDTs). While polymerase…”
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Ultrasensitive loop mediated isothermal amplification (US-LAMP) to detect malaria for elimination by Mohon, Abu Naser, Getie, Sisay, Jahan, Nusrat, Alam, Mohammad Shafiul, Pillai, Dylan R

“…Malaria elimination requires diagnostic methods able to detect parasite levels well below what is currently possible with microscopy and rapid diagnostic…”
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Detection of Plasmodium Infection by the illumigene Malaria Assay Compared to Reference Microscopy and Real-Time PCR by Rypien, Candace, Chow, Barbara, Chan, Wilson W, Church, Deirdre L, Pillai, Dylan R

“…Malaria is one of the leading causes of infectious disease in travelers returning from the tropics. The diagnosis of malaria is typically performed by…”
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Mutations in Plasmodium falciparum K13 propeller gene from Bangladesh (2009-2013) by Mohon, Abu Naser, Alam, Mohammad Shafiul, Bayih, Abebe Genetu, Folefoc, Asongna, Shahinas, Dea, Haque, Rashidul, Pillai, Dylan R

“…Bangladesh is a malaria hypo-endemic country sharing borders with India and Myanmar. Artemisinin combination therapy (ACT) remains successful in Bangladesh. An…”
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Amplicon Deep Sequencing Reveals Multiple Genetic Events Lead to Treatment Failure with Atovaquone-Proguanil in Plasmodium falciparum by Castañeda-Mogollón, Daniel, Toppings, Noah B, Kamaliddin, Claire, Lang, Raynell, Kuhn, Susan, Pillai, Dylan R

“…Atovaquone-proguanil (AP) is used as treatment for uncomplicated malaria, and as a chemoprophylactic agent against Plasmodium falciparum. Imported malaria…”
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The Role of Ultrasensitive Molecular Methods for Detecting Malaria—The Broader Perspective by Kamaliddin, Claire, Sutherland, Colin J, Houze, Sandrine, Cottrell, Gilles, Briand, Valerie, Castaneda Mogollon, Daniel, Pillai, Dylan R

“…Abstract Ultrasensitive molecular diagnostics are lowering the limit of detection for malaria parasites in the blood and providing insights not captured by…”
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Digital Droplet PCR to Track SARS-CoV-2 Outbreak in a Hospital Transitional Care Unit by Linton, Kathryn, Oberding, Lisa K., Ward, Linda, Kim, Joseph, Pillai, Dylan R.

“…We describe an outbreak of SARS-CoV-2 on a transition unit composed of elderly patients awaiting placement. Environmental and patient sample analyses using…”
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Clostridioides difficile Near-Patient Testing Versus Centralized Testing: A Pragmatic Cluster Randomized Crossover Trial by Doolan, Cody P, Sahragard, Babak, Leal, Jenine, Sharma, Anuj, Kim, Joseph, Spackman, Eldon, Hollis, Aidan, Pillai, Dylan R

“…Abstract Background Management of suspected Clostridioides difficile infection (CDI) in the hospital setting typically results in patient isolation, laboratory…”
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A multicenter study investigating SARS-CoV-2 in tertiary-care hospital wastewater. viral burden correlates with increasing hospitalized cases as well as hospital-associated transmissions and outbreaks by Acosta, Nicole, Bautista, María A., Hollman, Jordan, McCalder, Janine, Beaudet, Alexander Buchner, Man, Lawrence, Waddell, Barbara J., Chen, Jianwei, Li, Carmen, Kuzma, Darina, Bhatnagar, Srijak, Leal, Jenine, Meddings, Jon, Hu, Jia, Cabaj, Jason L., Ruecker, Norma J., Naugler, Christopher, Pillai, Dylan R., Achari, Gopal, Ryan, M. Cathryn, Conly, John M., Frankowski, Kevin, Hubert, Casey RJ, Parkins, Michael D.

“…•SARS-CoV-2 RNA was detected in the wastewater of three hospitals.•Abundance of SARS-CoV-2 correlated with increasing burden of active-COVID-19 cases.•Hospital…”
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A Countrywide Survey of hrp2/3 Deletions and kelch13 Mutations Co-occurrence in Ethiopia by Kamaliddin, Claire, Burke-Gaffney, Jack, Ashraf, Shoaib, Castañeda-Mogollón, Daniel, Adamu, Aderaw, Mekonen Tefa, Bacha, Wijesinghe, Ayesha, Pussegoda, Enaara, Feleke, Sindew Mekasha, Pillai, Dylan R

“…Abstract Malaria elimination relies on detection of Plasmodium falciparum histidine-rich proteins 2/3 (HRP2/3) through rapid diagnostic tests (RDTs) and…”
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Reply to Awandu et al by Golassa, Lemu, Cheaveau, James, Mohon, Abu Naser, Pillai, Dylan R

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Rapid Pneumococcal Evolution in Response to Clinical Interventions by Croucher, Nicholas J, Harris, Simon R, Fraser, Christophe, Quail, Michael A, Burton, John, van der Linden, Mark, McGee, Lesley, von Gottberg, Anne, Song, Jae Hoon, Ko, Kwan Soo, Pichon, Bruno, Baker, Stephen, Parry, Christopher M, Lambertsen, Lotte M, Shahinas, Dea, Pillai, Dylan R, Mitchell, Timothy J, Dougan, Gordon, Tomasz, Alexander, Klugman, Keith P, Parkhill, Julian, Hanage, William P, Bentley, Stephen D

“…Epidemiological studies of the naturally transformable bacterial pathogen Streptococcus pneumoniae have previously been confounded by high rates of…”
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Asymptomatic malaria in the clinical and public health context by Cheaveau, James, Mogollon, Daniel Castaneda, Mohon, Md Abu Naser, Golassa, Lemu, Yewhalaw, Delenasaw, Pillai, Dylan R

“…: Historically, the global community has focused on the control of symptomatic malaria. However, interest in asymptomatic malaria has been growing,…”
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A Unique Plasmodium falciparum K13 Gene Mutation in Northwest Ethiopia by Bayih, Abebe Genetu, Getnet, Gebeyaw, Alemu, Abebe, Getie, Sisay, Mohon, Abu Naser, Pillai, Dylan R

“…Artemisinin combination therapy (ACT) is the first line to treat uncomplicated Plasmodium falciparum malaria worldwide. Artemisinin treatment failures are on…”
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Performance of four commercial real-time PCR assays for the detection of bacterial enteric pathogens in clinical samples by Berenger, Byron M., Chui, Linda, Ferrato, Christina, Lloyd, Tracie, Li, Vincent, Pillai, Dylan R.

“…•This study compared four commercial RT-PCR tests for bacterial gastroenteritis to culture•There was >90% agreement for C. jejuni, Salmonella, and…”
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Multiplex real-time quantitative PCR, microscopy and rapid diagnostic immuno-chromatographic tests for the detection of Plasmodium spp: performance, limit of detection analysis and quality assurance by Khairnar, Krishna, Martin, Donald, Lau, Rachel, Ralevski, Filip, Pillai, Dylan R

“…Accurate laboratory diagnosis of malaria species in returning travelers is paramount in the treatment of this potentially fatal infectious disease. A total of…”
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