Search Results - "Pilgrim, David B."

Myomesin is part of an integrity pathway that responds to sarcomere damage and disease by Prill, Kendal, Carlisle, Casey, Stannard, Megan, Windsor Reid, Pamela J, Pilgrim, David B

“…The structure and function of the sarcomere of striated muscle is well studied but the steps of sarcomere assembly and maintenance remain under-characterized…”
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Antagonistic Behaviors of NMY-1 and NMY-2 Maintain Ring Channels in the C. elegans Gonad by Coffman, Valerie C., Kachur, Torah M., Pilgrim, David B., Dawes, Adriana T.

“…Contractile rings play critical roles in a number of biological processes, including oogenesis, wound healing, and cytokinesis. In many cases, the activity of…”
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Still Heart Encodes a Structural HMT, SMYD1b, with Chaperone-Like Function during Fast Muscle Sarcomere Assembly by Prill, Kendal, Windsor Reid, Pamela, Wohlgemuth, Serene L, Pilgrim, David B

“…The vertebrate sarcomere is a complex and highly organized contractile structure whose assembly and function requires the coordination of hundreds of proteins…”
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The myosin co-chaperone UNC-45 is required for skeletal and cardiac muscle function in zebrafish by Wohlgemuth, Serene L., Crawford, Bryan D., Pilgrim, David B.

“…The assembly of myosin into higher order structures is dependent upon accessory factors that are often tissue-specific. UNC-45 acts as such a molecular…”
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The titin A-band rod domain is dispensable for initial thick filament assembly in zebrafish by Myhre, J. Layne, Hills, Jordan A., Prill, Kendal, Wohlgemuth, Serene L., Pilgrim, David B.

“…The sarcomeres of skeletal and cardiac muscle are highly structured protein arrays, consisting of thick and thin filaments aligned precisely to one another and…”
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Gdf6a is required for the initiation of dorsal–ventral retinal patterning and lens development by French, Curtis R., Erickson, Timothy, French, Danielle V., Pilgrim, David B., Waskiewicz, Andrew J.

“…Dorsal–ventral patterning of the vertebrate retina is essential for accurate topographic mapping of retinal ganglion cell (RGC) axons to visual processing…”
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Correction: Still Heart Encodes a Structural HMT, SMYD1b, with Chaperone-Like Function during Fast Muscle Sarcomere Assembly by Prill, Kendal, Reid, Pamela Windsor, Wohlgemuth, Serene L, Pilgrim, David B

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Myosin assembly, maintenance and degradation in muscle: Role of the chaperone UNC-45 in myosin thick filament dynamics by Kachur, Torah M, Pilgrim, David B

“…Myofibrillogenesis in striated muscle cells requires a precise ordered pathway to assemble different proteins into a linear array of sarcomeres. The sarcomere…”
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At the Start of the Sarcomere: A Previously Unrecognized Role for Myosin Chaperones and Associated Proteins during Early Myofibrillogenesis by Myhre, J. Layne, Pilgrim, David B.

“…The development of striated muscle in vertebrates requires the assembly of contractile myofibrils, consisting of highly ordered bundles of protein filaments…”
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The Axenfeld-Rieger Syndrome Gene FOXC1 Contributes to Left-Right Patterning by Chrystal, Paul W, French, Curtis R, Jean, Francesca, Havrylov, Serhiy, van Baarle, Suey, Peturson, Ann-Marie, Xu, Pengfei, Crump, J Gage, Pilgrim, David B, Lehmann, Ordan J, Waskiewicz, Andrew J

“…Precise spatiotemporal expression of the - - cascade in the lateral plate mesoderm establishes the left-right axis, which provides vital cues for correct organ…”
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Ontogeny and regulation of matrix metalloproteinase activity in the zebrafish embryo by in vitro and in vivo zymography by Crawford, Bryan D., Pilgrim, David B.

“…Remodeling of the extracellular matrix (ECM) during development, angiogenesis, wound healing, tumor metastasis, and other morphogenetic processes depends on…”
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Cellular differentiation in primary cell cultures from single zebrafish embryos as a model for the study of myogenesis by Myhre, J Layne, Pilgrim, David B

“…Culturing cells in vitro can produce a uniform population for the study of cellular differentiation, which is especially useful for the quantification of gene…”
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UNC-119 homolog required for normal development of the zebrafish nervous system by Manning, Angela G., Crawford, Bryan D., Waskiewicz, Andrew J., Pilgrim, David B.

“…The UNC‐119 proteins, found in all metazoans examined, are highly conserved at both the sequence and functional levels. In the invertebrates Caenorhabditis…”
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RNA interference of peroxisome-related genes in C. elegans: a new model for human peroxisomal disorders by Petriv, Oleh I, Pilgrim, David B, Rachubinski, Richard A, Titorenko, Vladimir I

“…1 Department of Cell Biology, University of Alberta, Edmonton T6G 2H7 2 Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada T6G…”
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Mitochondrial Respiratory Chain Deficiency inCaenorhabditis elegans Results in Developmental Arrest and Increased Life Span by Tsang, William Y., Sayles, Leanne C., Grad, Leslie I., Pilgrim, David B., Lemire, Bernard D.

“…The growth and development of Caenorhabditis elegans are energy-dependent and rely on the mitochondrial respiratory chain (MRC) as the major source of ATP. The…”
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Mitochondrial respiratory chain deficiency in Caenorhabditis elegans results in developmental arrest and increased life span by Tsang, W Y, Sayles, L C, Grad, L I, Pilgrim, D B, Lemire, B D

“…The growth and development of Caenorhabditis elegans are energy-dependent and rely on the mitochondrial respiratory chain (MRC) as the major source of ATP. The…”
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The Unc-119 Family of Neural Proteins is Functionally Conserved Between Humans, Drosophila and C. Elegans by Maduro, Morris F., Gordon, Michael, Jacobs, Roger, Pilgrim, David B.

“…C. elegans animals mutant for the unc-119 gene exhibit movement, sensory and behavioral abnormalities. Consistent with a nervous system role, unc-119 reporter…”
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Mutant alcohol dehydrogenase (ADH III) presequences that affect both in vitro mitochondrial import and in vitro processing by the matrix protease by MOONEY, D. T, PILGRIM, D. B, YOUNG, E. T

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Mutant Alcohol Dehydrogenase (ADH III) Presequences That Affect Both In Vitro Mitochondrial Import and In Vitro Processing by the Matrix Protease by Mooney, Duane T., Pilgrim, David B., T. Young, Elton

“…Point mutations in the presequence of the mitochondrial alcohol dehydrogerase isoenzyme (ADH III) have been shown to affect either the import of the precursor…”
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Expression of a Drosophila melanogaster amber suppressor tRNA(Ser) in Caenorhabditis elegans by Pilgrim, D B, Bell, J B

“…The purpose of this study was to test a cloned amber-suppressing tRNA(Ser) gene derived from Drosophila melanogaster for its ability to produce amber…”
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