Search Results - "Pilgrim, Dave"
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Chaperones and the Proteasome System: Regulating the Construction and Demolition of Striated Muscle
Published in International journal of molecular sciences (22-12-2017)“…Protein folding factors (chaperones) are required for many diverse cellular functions. In striated muscle, chaperones are required for contractile protein…”
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2
Unc45b is essential for early myofibrillogenesis and costamere formation in zebrafish
Published in Developmental biology (01-06-2014)“…Despite the prevalence of developmental myopathies resulting from muscle fiber defects, the earliest stages of myogenesis remain poorly understood. Unc45b is a…”
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3
UNC-45 is required for NMY-2 contractile function in early embryonic polarity establishment and germline cellularization in C. elegans
Published in Developmental biology (15-02-2008)“…The Caenorhabditis elegans UNC-45 protein is required for proper body wall muscle assembly and acts as a molecular co-chaperone for type II myosins. In…”
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4
Mmp25β facilitates elongation of sensory neurons during zebrafish development
Published in Genesis (New York, N.Y. : 2000) (01-10-2014)“…Summary Matrix metalloproteinases (MMPs) are a large and complex family of zinc‐dependent endoproteinases widely recognized for their roles in remodeling the…”
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5
Comparative Genetics of Sex Determination: Masculinizing Mutations in Caenorhabditis briggsae
Published in Genetics (Austin) (01-03-2008)“…The nematodes Caenorhabditis elegans and C. briggsae independently evolved self-fertile hermaphroditism from gonochoristic ancestors. C. briggsae has variably…”
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6
Sex-determination gene and pathway evolution in nematodes
Published in BioEssays (01-03-2003)“…The pathway that controls sexual fate in the nematode Caenorhabditis elegans has been well characterized at the molecular level. By identifying differences…”
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7
Mmp25[beta] facilitates elongation of sensory neurons during zebrafish development
Published in Genesis (New York, N.Y. : 2000) (01-10-2014)“…Summary Matrix metalloproteinases (MMPs) are a large and complex family of zinc-dependent endoproteinases widely recognized for their roles in remodeling the…”
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8
Genetic Flexibility in the Convergent Evolution of Hermaphroditism in Caenorhabditis Nematodes
Published in Developmental cell (01-04-2006)“…The self-fertile hermaphrodites of C. elegans and C. briggsae evolved from female ancestors by acquiring limited spermatogenesis. Initiation of C. elegans…”
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9
Does the Sun Know What Day It Is?
Published in Science (American Association for the Advancement of Science) (20-09-2002)Get full text
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10
Maternal UNC-45 is involved in cytokinesis and colocalizes with non-muscle myosin in the early Caenorhabditis elegans embryo
Published in Journal of cell science (15-10-2004)“…The Caenorhabditis elegans UNC-45 protein contains tetratricopeptide repeats and a domain with similarity to fungal proteins, and it differentially colocalizes…”
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Caenorhabditis elegans UNC-45 Is a Component of Muscle Thick Filaments and Colocalizes with Myosin Heavy Chain B, but Not Myosin Heavy Chain A
Published in The Journal of cell biology (24-01-2000)“…In the nematode Caenorhabditis elegans, animals mutant in the gene encoding the protein product of the unc-45 gene (UNC-45) have disorganized muscle thick…”
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12
CeRep25B forms chromosome-specific minisatellite arrays in Caenorhabditis elegans
Published in Genome research (01-11-1998)“…With the completion of the Genome Sequencing Project, it is now possible to rapidly and accurately determine the frequency and position of a particular repeat…”
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13
Molecular Evolution of a Sex Determination Protein: FEM-2 (PP2C) in Caenorhabditis
Published in Genetics (Austin) (01-07-1998)“…Somatic sex determination in Caenorhabditis elegans involves a signal transduction pathway linking a membrane receptor to a transcription factor. The fem-2…”
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14
Roles for Mating and Environment in C. elegans Sex Determination
Published in Science (American Association for the Advancement of Science) (07-11-2003)“…In Caenorhabditis elegans the two sexes, hermaphrodites and males, are thought to be irreversibly determined at fertilization by the ratio of X chromosomes to…”
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15
GERp95, a membrane-associated protein that belongs to a family of proteins involved in stem cell differentiation
Published in Molecular biology of the cell (01-10-1999)“…A panel of mAbs was elicited against intracellular membrane fractions from rat pancreas. One of the antibodies reacted with a 95-kDa protein that localizes…”
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16
Evolution of the PP2C family in Caenorhabditis: rapid divergence of the sex-determining protein FEM-2
Published in Journal of molecular evolution (01-02-2002)“…To investigate the causes and functional significance of rapid sex-determining protein evolution we compared three Caenorhabditis elegans genes encoding…”
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The C. elegans sex-determining gene fem-2 encodes a putative protein phosphatase
Published in Molecular biology of the cell (01-09-1995)“…The genetic and molecular analysis of genes involved in the regulation of sex determination in Caenorhabditis elegans suggests that the gene fem-2 plays an…”
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The genetic and RFLP characterization of the left end of linkage group III in Caenorhabditis elegans
Published in Genome (01-08-1993)“…A genetic approach was taken to identify new transposable element Tc1-dependent polymorphisms on the left end of linkage group III in the nematode…”
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Sex and the single worm: sex determination in the nematode C. elegans
Published in Mechanisms of Development (01-05-1999)“…The study of sex determination in model organisms has been especially fruitful in increasing our understanding of developmental biology, gene regulation and…”
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unc-45 gene of Caenorhabditis elegans encodes a muscle-specific tetratricopeptide repeat-containing protein
Published in Cell motility and the cytoskeleton (1999)“…The unc‐45 gene of the nematode, Caenorhabditis elegans, is essential for muscle organization and embryonic development. Genetic evidence suggests the unc‐45…”
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