Search Results - "Pilewski, J"

A Randomized Controlled Trial of a Mobile Health Intervention to Promote Self‐Management After Lung Transplantation by DeVito Dabbs, A., Song, M. K., Myers, B. A., Li, R., Hawkins, R. P., Pilewski, J. M., Bermudez, C. A., Aubrecht, J., Begey, A., Connolly, M., Alrawashdeh, M., Dew, M. A.

“…Lung transplant recipients are encouraged to perform self‐management behaviors, including (i) monitoring health indicators, (ii) adhering to their regimen, and…”
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Targeting the IL-22/IL-22BP axis enhances tight junctions and reduces inflammation during influenza infection by Hebert, K. D., Mclaughlin, N., Galeas-Pena, M., Zhang, Z., Eddens, T., Govero, A., Pilewski, J. M., Kolls, J. K., Pociask, D. A.

“…The seasonal burden of influenza coupled with the pandemic outbreaks of more pathogenic strains underscore a critical need to understand the pathophysiology of…”
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Mechanical Ventilation and Extracorporeal Membrane Oxygenation as a Bridging Strategy to Lung Transplantation: Significant Gains in Survival by Hayanga, A. J., Du, A. L., Joubert, K., Tuft, M., Baird, R., Pilewski, J., Morrell, M., D'Cunha, J., Shigemura, N.

“…Mechanical ventilation (MV) and extracorporeal membrane oxygenation (ECMO) are increasingly used to bridge patients to lung transplantation. We investigated…”
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Proteasome Inhibitor Carfilzomib‐Based Therapy for Antibody‐Mediated Rejection of the Pulmonary Allograft: Use and Short‐Term Findings by Ensor, C. R., Yousem, S. A., Marrari, M., Morrell, M. R., Mangiola, M., Pilewski, J. M., D'Cunha, J., Wisniewski, S. R., Venkataramanan, R., Zeevi, A., McDyer, J. F.

“…We present this observational study of lung transplant recipients (LTR) treated with carfilzomib (CFZ)‐based therapy for antibody‐mediated rejection (AMR) of…”
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Long‐Term Follow‐up of a Randomized Controlled Trial Evaluating a Mobile Health Intervention for Self‐Management in Lung Transplant Recipients by Rosenberger, E. M., DeVito Dabbs, A. J., DiMartini, A. F., Landsittel, D. P., Pilewski, J. M., Dew, M. A.

“…Mobile health interventions may help transplant recipients follow their complex medical regimens. Pocket Personal Assistant for Tracking Health (Pocket PATH)…”
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Association between MRSA Colonization and Chronic Lung Allograft Dysfunction in Lung Transplantation for Cystic Fibrosis by Kiel, S., Marrari, M., Robinson, K., Zeevi, A., Sanchez, P., Morrell, M., Pilewski, J., Nolley, E.P.

“…Incidence of and risk factors for chronic lung allograft dysfunction (CLAD) in lung transplantation for cystic fibrosis (CF) are not established. Methicillin…”
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Thrombospondin-1 triggers macrophage IL-10 production and promotes resolution of experimental lung injury by Zhao, Y, Xiong, Z, Lechner, E J, Klenotic, P A, Hamburg, B J, Hulver, M, Khare, A, Oriss, T, Mangalmurti, N, Chan, Y, Zhang, Y, Ross, M A, Stolz, D B, Rosengart, M R, Pilewski, J, Ray, P, Ray, A, Silverstein, R L, Lee, J S

“…Mononuclear phagocyte recognition of apoptotic cells triggering suppressive cytokine signaling is a key event in inflammation resolution from injury. Mice…”
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Pattern and Predictors of Hospital Readmission During the First Year After Lung Transplantation by Alrawashdeh, M., Zomak, R., Dew, M. A., Sereika, S., Song, M. K., Pilewski, J. M., DeVito Dabbs, A.

“…Hospital readmission after lung transplantation negatively affects quality of life and resource utilization. A secondary analysis of data collected…”
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Lung Transplantation in Patients With Prior Cardiothoracic Surgical Procedures by Shigemura, N., Bhama, J., Gries, C. J., Kawamura, T., Crespo, M., Johnson, B., Zaldonis, D., Pilewski, J., Toyoda, Y., Bermudez, C.

“…The full spectrum of prior cardiothoracic procedures in lung transplant candidates and the impact of prior procedures on outcomes after lung transplantation…”
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EPS1.5 A phase 3 extension study evaluating the safety and efficacy of long-term ivacaftor (IVA) in patients with cystic fibrosis (CF) and phenotypic or molecular evidence of residual CFTR function by Pilewski, J, Higgins, M, Cooke, J, Nick, J.A

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Recipient-Derived Immune Cell Phenotyping of Bronchoalveolar Lavage Identifies Patients with Biopsy Proven Early Acute Cellular Rejection after Lung Transplantation: A Pilot Study by Snyder, M.E., Popesu, I.D., Morrell, M., Johnson, B., Kilaru, S., Lendermon, E., Pilewski, J., Lakkis, F.G., McDyer, J.F.

“…Acute cellular rejection (ACR) is associated with the ultimate development of chronic lung allograft dysfunction. Transbronchial biopsy, the gold standard for…”
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Epidemiology and Outcomes of Deep Surgical Site Infections Following Lung Transplantation by Shields, R. K., Clancy, C. J., Minces, L. R., Shigemura, N., Kwak, E. J., Silveira, F. P., Abdel‐Massih, R. C., Bhama, J. K., Bermudez, C. A., Pilewski, J. M., Crespo, M., Toyoda, Y., Nguyen, M. H.

“…We conducted a retrospective study of deep surgical site infections (SSIs) among consecutive patients who underwent lung transplantation (LTx) at a single…”
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Voriconazole Prophylaxis in Lung Transplant Recipients by Husain, S., Paterson, D. L., Studer, S., Pilewski, J., Crespo, M., Zaldonis, D., Shutt, K., Pakstis, D. L., Zeevi, A., Johnson, B., Kwak, E. J., McCurry, K. R.

“…Lung transplant recipients have one of the highest rates of invasive aspergillosis (IA) in solid organ transplantation. We used a single center, nonrandomized,…”
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Looking Beyond Respiratory Cultures: Microbiome‐Cytokine Signatures of Bacterial Pneumonia and Tracheobronchitis in Lung Transplant Recipients by Shankar, J., Nguyen, M. H., Crespo, M. M., Kwak, E. J., Lucas, S. K., McHugh, K. J., Mounaud, S., Alcorn, J. F., Pilewski, J. M., Shigemura, N., Kolls, J. K., Nierman, W. C., Clancy, C. J.

“…Bacterial pneumonia and tracheobronchitis are diagnosed frequently following lung transplantation. The diseases share clinical signs of inflammation and are…”
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Transcriptome Analysis of Airway Brushes in Lung Transplant Recipients with and without Chronic Lung Allograft Dysfunction by Iasella, C.J., Snyder, M., Popescu, I., Wei, J., Hoji, A., Zhang, Y., Xu, W., Iouchmanov, V., Brown, M., Lendermon, E., Johnson, B., Kilaru, S., Morrell, M., Pilewski, J., Greenland, J., Chen, K., McDyer, J.F.

“…Chronic lung allograft dysfunction (CLAD) in lung transplant recipients (LTRs) limits long-term survival compared to other solid organ transplants. Underlying…”
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Health-Related Quality of Life Impairments and Benefits 15-19 Years after Lung or Heart Transplant by Dew, M.A., DeVito Dabbs, A.J., DiMartini, A.F., Ma, Y., McNulty, M.L., Posluszny, D.M., Myaskovsky, L., Sciortino, C.M., Sanchez, P.G., Pilewski, J.M.

“…Growing numbers of patients are entering the very late term period (15+ yrs) of survivorship after cardiothoracic transplant (CTx). Their health-related…”
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Idiopathic Pulmonary Fibrosis Lung Transplant Recipients are at Increased Risk for Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disorder by Iasella, C.J., Winters, S., Kois, A., Cho, J., Hannan, S.J., Koshy, R., Moore, C., Lendermon, E.A., Pilewski, J., Morrell, M., Sanchez, P.G., Kass, D., Alder, J.K., Nouriea, S.M., McDyer, J.

“…Epstein-Barr virus (EBV)-associated post-transplant lymphoproliferative disorder (PTLD) is a serious complication in lung transplant recipients (LTRs)…”
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Persistence of Increased Type-1 Alloeffector CD4+ T Cell Responses from ACR into CLAD in Lung Transplant Recipients by Popescu, I., Iasella, C., Lendermon, E., Sembrat, J., Saul, M., Chen, X., Seyed, N., Gonsallus, B., Koshy, R., Hannan, S., Zhang, Y., Xu, W., Iouchmanov, V., Brown, M., Snyder, M., Johnson, B., Kilaru, S., Morrell, M., Pilewski, J., Chen, K., McDyer, J.F.

“…Chronic lung allograft dysfunction (CLAD) significantly limits long-term survival in lung transplant recipients (LTRs) and episodes of acute cellular rejection…”
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Microbial Communities and Cytokine Responses Associated With Respiratory Tract Infections Following Lung Transplant (LTx) by Clancy, C, Shankar, J, Crespo, M, Pilewski, J, Bermudez, C, Nierman, W, Nguyen, M

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Absorptive clearance of DTPA as an aerosol-based biomarker in the cystic fibrosis airway by Corcoran, T. E, Thomas, K. M, Myerburg, M. M, Muthukrishnan, A, Weber, L, Frizzell, R, Pilewski, J. M

“…Biomarkers providing in vivo quantification of the basic elements of cystic fibrosis (CF) lung disease are needed. A study was performed to determine whether…”
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