Search Results - "Piletz, J E"

Relevance of Imidazoline Receptors and Agmatine to Psychiatry: A Decade of Progress by HALARIS, A, PILETZ, J E.

“…: The cardiovascular relevance of imidazoline receptors (IR) has received tremendous attention since their discovery in 1984. However, evidence also has…”
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Agmatine Crosses the Blood-Brain Barrier by PILETZ, J E., MAY, P J., WANG, G, ZHU, H

“…: The question of whether agmatine crosses the blood‐brain barrier has not been directly addressed, even though peripheral injection of this compound has…”
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Comparison of the properties of agmatine and endogenous clonidine-displacing substance at imidazoline and alpha-2 adrenergic receptors by Piletz, J E, Chikkala, D N, Ernsberger, P

“…Nonadrenergic imidazoline receptors (I receptors) mediate the central antihypertensive effects of clonidine. Agmatine, an arginine metabolite that is…”
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Cell Signaling by Imidazoline-1 Receptor Candidate, IRAS, and the Nischarin Homologue by PILETZ, JE, WANG, G, ZHU, H

“…: IRAS transfection into Chinese hamster ovary (CHO) or pheochromocytoma (PC‐12) cell lines leads to the appearance of nonadrenergic binding sites for…”
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Nonadrenergic imidazoline binding sites on human platelets by Piletz, J E, Sletten, K

“…Human platelets are shown to possess at least two high-affinity, imidazol(in)e-preferring binding sites that are pharmacologically distinct from alpha-2…”
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Imidazoline receptors associated with noradrenergic terminals in the rostral ventrolateral medulla mediate the hypotensive responses of moxonidine but not clonidine by Chan, C.K.S., Burke, S.L., Zhu, H., Piletz, J.E., Head, G.A.

“…We determined whether the cardiovascular actions of central anti-hypertensive agents clonidine and moxonidine are dependent on noradrenergic or serotonergic…”
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IRAS, the human homologue of Nischarin, prolongs survival of transfected PC12 cells by Dontenwill, M, Pascal, G, Piletz, J E, Chen, M, Baldwin, J, Rondé, P, Dupuy, L, Urosevic, D, Greney, H, Takeda, K, Bousquet, P

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Elevated p-selectin on platelets in depression: response to bupropion by Piletz, J.E, Zhu, H, Madakasira, S, Pazzaglia, P, Lindsay DeVane, C, Goldman, N, Halaris, A

“…Increased platelet activation has been suggested as a possible reason for the increased vulnerability of depressed patients to ischemic heart disease (IHD)…”
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Atypical [3H]Clonidine Binding Sites in Human Caudate and Platelets on Cryostat-cut Sections by ZHU, H, HALARIS, A, PILETZ, JE

“…: Pharmacological characterization is described for a human imidazoline binding site (I‐site) labeled by [3H]clonidine using standard autoradiographic method…”
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IRAS Splice Variants by PILETZ, JE, DELEERSNIJDER, W, ROTH, BL, ERNSBERGER, P, ZHU, H, ZIEGLER, D

“…: The human I1‐imidazoline receptor candidate gene, iras, has previously been cloned and mapped to locus 3p21.1–9 (also known as Nischarin; accession…”
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Structure-Activity Analysis of Guanidine Group in Agmatine for Brain Agmatinase by HUANG, M-J, REGUNATHAN, S, BOTTA, M, LEE, K, MCCLENDON, E, YI, G B, PEDERSEN, M L, BERKOWITZ, D B, WANG, G, TRAVAGLI, M, PILETZ, J E

“…: To identify a selective inhibitor of mammalian agmatinase, screening was performed on four analogues of agmatine with modifications directly to the guanidine…”
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Imidazoline receptor proteins are regulated in platelet-precursor MEG-01 cells by agonists and antagonists by Ivanov, T.R., Feng, Y., Wang, H., Regunathan, S., Reis, D.J., Chikkala, D.N., Gupta, P., Jones, J.C., Piletz, J.E.

“…The I 1-imidazoline receptor is a novel brainstem modulator of sympathetic outflow that is elevated on platelets and in brains of depressed patients. A…”
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Co-detection by two imidazoline receptor protein antisera of a novel 85 kilodalton protein by Ivanov, Tina R., Zhu, He, Regunathan, Soundararajan, Reis, Donald J., Dontenwill, Monique, Vonthron, Catherine, Bousquet, Pascal, Piletz, John E.

“…Imidazoline receptors (I-receptors) are considered as potential therapeutic targets for a spectrum of stress-induced illnesses. Yet, I-receptors remain poorly…”
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Effectiveness of anticholinergics and neuroleptic dose reduction on neuroleptic-induced pleurothotonus (the Pisa syndrome) by Suzuki, T, Hori, T, Baba, A, Abe, S, Shiraishi, H, Moroji, T, Piletz, J E

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Effect of bupropion on immunodensity of putative imidazoline receptors on platelets of depressed patients by Zhu, He, Halaris, Angelos, Madakasira, Sudhakar, Pazzaglia, Peggy, Goldman, Nancy, DeVane, C.Lindsay, Andrew, Mike, Reis, Donald, Piletz, John E.

“…A substantial number of studies have demonstrated increased imidazoline receptors (I 1 binding sites) on platelets of depressed patients and downregulation…”
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The pisa syndrome (pleurothotonus) during antidepressant therapy by Suzuki, Toshihito, Kurita, Hirofumi, Hori, Takafumi, Sasaki, Megumi, Baba, Atsuomi, Shiraishi, Hiroyasu, Piletz, John E.

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Comparison of ligand binding affinities at human I1-imidazoline binding sites and the high affinity state of alpha-2 adrenoceptor subtypes by Piletz, J E, Zhu, H, Chikkala, D N

“…To identify selective compounds for nonadrenergic I1-imidazoline receptors (I1), the affinities of 22 ligands for [125I]p-iodoclonidine binding have been…”
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Intracellular membranes are more fluid in platelets of Alzheimer's disease patients by Piletz, J E, Sarasua, M, Whitehouse, P, Chotani, M

“…We studied 12 patients with probable Alzheimer's disease versus age- and sex-matched healthy control subjects. Platelets were subfractionated into…”
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Plasma MHPG response to yohimbine treatment in women with hypoactive sexual desire by PILETZ, J. E, SEGRAVES, K. B, FENG, Y.-Z, MAGUIRE, E, DUNGER, B, HALARIS, A

“…The use of yohimbine to treat impotence has suggested that decreased male sexual desire may relate to decreased activity of central noradrenergic neurons…”
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Apparent phase advance in diurnal MHPG rhythm in depression by Gwirtsman, H E, Halaris, A E, Wolf, A W, DeMet, E, Piletz, J E, Marler, M

“…Several investigators have proposed that diurnal rhythms, particularly that of the norepinephrine metabolite 3-methoxy-4-hydroxyphenylglycol (MHPG), show…”
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