Search Results - "Pilco‐Janeta, Daniel F."
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Analysis of microbiome in gastrointestinal stromal tumors: Looking for different players in tumorigenesis and novel therapeutic options
Published in Cancer science (01-08-2022)“…Preclinical forms of gastrointestinal stromal tumor (GIST), small asymptomatic lesions, called microGIST, are detected in approximately 30% of the general…”
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Co-targeting of ACK1 and KIT triggers additive anti-proliferative and -migration effects in imatinib-resistant gastrointestinal stromal tumors
Published in Biochimica et biophysica acta. Molecular basis of disease (01-06-2023)“…Most gastrointestinal stromal tumors (GIST) harbor mutated receptor tyrosine kinase (RTK) KIT/PDGFRA, which provides an attractive therapeutic target. However,…”
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Hyper-Dependence on NHEJ Enables Synergy between DNA-PK Inhibitors and Low-Dose Doxorubicin in Leiomyosarcoma
Published in Clinical cancer research (15-12-2023)“…Leiomyosarcoma (LMS) is an aggressive sarcoma for which standard chemotherapies achieve response rates under 30%. There are no effective targeted therapies…”
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E3 ubiquitin ligase Atrogin-1 mediates adaptive resistance to KIT-targeted inhibition in gastrointestinal stromal tumor
Published in Oncogene (02-12-2021)“…KIT/PDGFRA oncogenic tyrosine kinase signaling is the central oncogenic event in most gastrointestinal stromal tumors (GIST), which are human malignant…”
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Preferences regarding Disclosure of Risk for Parkinson's Disease in a Population‐based Study
Published in Movement disorders clinical practice (Hoboken, N.J.) (18-11-2024)“…Preferences for risk disclosure in population-based studies assessing Parkinson's disease (PD) risk have not been assessed so far.BACKGROUNDPreferences for…”
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Analysis of microbiome in GISTs: looking for different players in tumorigenesis and novel therapeutic options
Published in Cancer science (28-05-2022)“…Preclinical forms of Gastrointestinal stromal tumor (GIST), small asymptomatic lesions, called micro-GIST, are detected in ~30% of the general population. GIST…”
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