Search Results - "Pilc, A."

The effect of physical activity on the brain derived neurotrophic factor: from animal to human studies by Zoladz, J A, Pilc, A

“…It is well documented that physical activity can induce a number of various stimuli which are able to enhance the strength and endurance performance of…”
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Comparative effectiveness of abatacept, apremilast, secukinumab and ustekinumab treatment of psoriatic arthritis: a systematic review and network meta-analysis by Kawalec, P., Holko, P., Moćko, P., Pilc, A.

“…To assess the comparative effectiveness and safety of novel biologic therapies in psoriatic arthritis (PsA) and to establish the position of the non-anti-tumor…”
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Endurance training increases plasma brain-derived neurotrophic factor concentration in young healthy men by Zoladz, J A, Pilc, A, Majerczak, J, Grandys, M, Zapart-Bukowska, J, Duda, K

“…It is believed that brain derived neurotrophic factor (BDNF) plays an important role in neuronal growth, transmission, modulation and plasticity. Single bout…”
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Neuroprotective effects of metabotropic glutamate receptor group II and III activators against MPP(+)-induced cell death in human neuroblastoma SH-SY5Y cells: The impact of cell differentiation state by Jantas, D., Greda, A., Golda, S., Korostynski, M., Grygier, B., Roman, A., Pilc, A., Lason, W.

“…Recent studies have documented that metabotropic glutamate receptors from group II and III (mGluR II/III) are a potential target in the symptomatic treatment…”
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Neuroprotective effects of mGluR II and III activators against staurosporine- and doxorubicin-induced cellular injury in SH-SY5Y cells: New evidence for a mechanism involving inhibition of AIF translocation by Jantas, D., Greda, A., Leskiewicz, M., Grygier, B., Pilc, A., Lason, W.

“…•mGluR II/III activators showed better neuroprotective profile in undifferentiated SH-SY5Y cells.•Relatively the highest protection was mediated by mGluR8 and…”
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Group II mGlu receptor antagonist LY341495 enhances the antidepressant-like effects of scopolamine in behavioural models of depression by Pałucha-Poniewiera, A, Podkowa, K, Pilc, A

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The antipsychotic-like activity of VU152100, a muscarinic M4 receptor positive allosteric modulator, in animal models of schizophrenia by Wieronska, J.M, Woźniak, M, Cieślik, P, Pilc, A

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Breast cancer surgery decreases serum brain-derived neurotrophic factor concentrations in middle aged women: relationship to the serum C-reactive protein concentration by Zoladz, J A, Nowak, L R, Majerczak, J, Kulpa, J, Pilc, A, Duda, K

“…The aim of this study was to establish the effect of breast cancer surgery in middle aged women on the serum and plasma brain-derived neurotrophic factor…”
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The possible role of mGluR4 in drug addiction by Pilc, A, Filip, M, Pałucha-Poniewiera, A, Zaniewska, M

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involvement of NMDA and AMPA receptors in the mechanism of antidepressant-like action of zinc in the forced swim test by Szewczyk, B, Poleszak, E, Sowa-Kućma, M, Wróbel, A, Słotwiński, S, Listos, J, Wlaź, P, Cichy, A, Siwek, A, Dybała, M, Gołembiowska, K, Pilc, A, Nowak, Gabriel

“…Antidepressant-like activity of zinc in the forced swim test (FST) was demonstrated previously. Enhancement of such activity by joint administration of zinc…”
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The reversal of cognitive, but not negative or positive symptoms of schizophrenia, by the mGlu2/3 receptor agonist, LY379268, is 5-HT1A dependent by Wierońska, Joanna M., Sławińska, A., Stachowicz, K., Łasoń-Tyburkiewicz, M., Gruca, P., Papp, M., Pilc, A.

“…•LY379268 is active in the model of cognitive symptoms of psychosis.•LY379268-induced reversal of cognitive symptoms of psychosis is…”
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Co-administration of COX-2 inhibitor NS-398 enhances antidepressant effect of mGluR5 antagonist MTEP in mice by Pańczyszyn-Trzewik, P, Misztak, P, Sowa-Kućma, M, Szewczyk, B, Nowak, G, Pilc, A, Stachowicz, K

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Antidepressant‐like activity of CGP 36742 and CGP 51176, selective GABA B receptor antagonists, in rodents by Nowak, G, Partyka, A, Pałucha, A, Szewczyk, B, Wierońska, J M, Dybała, M, Metz, M, Librowski, T, Froestl, W, Papp, M, Pilc, A

“…Background and purpose: A crucial role for the GABA B receptor in depression was proposed several years ago, but there are limited data to support this…”
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Decreased sensitivity to paroxetine-induced inhibition of peripheral blood mononuclear cell growth in depressed and antidepressant treatment-resistant patients by Rzezniczek, S, Obuchowicz, M, Datka, W, Siwek, M, Dudek, D, Kmiotek, K, Oved, K, Shomron, N, Gurwitz, D, Pilc, A

“…Major depression disorder (MDD) is the most widespread mental disorder. Selective serotonin reuptake inhibitors (SSRIs) are used as first-line MDD treatment…”
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The GABAB receptor agonist CGP44532 and the positive modulator GS39783 reverse some behavioural changes related to positive syndromes of psychosis in mice by Wierońska, JM, Kusek, M, Tokarski, K, Wabno, J, Froestl, W, Pilc, A

“…BACKGROUND AND PURPOSE An important role of GABAergic neurotransmission in schizophrenia was proposed a long time ago, but there is limited data to support…”
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P.2.a.008 Pro-depressive-like effects of mGlu4 selective agonist LSP4–2022 in mice by Rzezniczek, S, Podkowa, K, Marciniak, M, Acher, F, Pilc, A, Palucha-Poniewiera, A

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The group III mGlu receptor agonist ACPT-I exerts anxiolytic-like but not antidepressant-like effects, mediated by the serotonergic and GABA-ergic systems by Stachowicz, K., Kłodzińska, A., Palucha-Poniewiera, A., Schann, S., Neuville, P., Pilc, A.

“…Our earlier studies have demonstrated that (1 S,3 R,4 S)-1-aminocyclo-pentane-1,3,4-tricarboxylic acid ACPT-I, a group III mGlu receptor agonist, produced…”
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The influence of group III metabotropic glutamate receptor stimulation by (1S,3R,4S)-1-aminocyclo-pentane-1,3,4-tricarboxylic acid on the parkinsonian-like akinesia and striatal proenkephalin and prodynorphin mRNA expression in rats by Konieczny, J, Wardas, J, Kuter, K, Pilc, A, Ossowska, K

“…Abstract Group III metabotropic glutamate receptors (mGluRs) are widely distributed in the basal ganglia, especially on the terminals of pathways which seem to…”
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P.1.009 Cell synchronisation as a tool to optimise expression of metabotropic glutamate receptors in inducible mammalian expression system by Chruscicka, B, Branski, P, Burnat, G, Pilc, A

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Potential anxiolytic‐ and antidepressant‐like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist by Tatarczyńska, Ewa, Kłodzińska, Aleksandra, Chojnacka‐Wójcik, Ewa, Pałucha, Agnieszka, Gasparini, Fabrizio, Kuhn, Rainer, Pilc, Andrzej

“…Several lines of evidence suggest a crucial involvement of glutamate in the mechanism of action of anxiolytic and/or antidepressant drugs. The involvement of…”
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