Search Results - "Pila, Emmanuel A."
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A Novel Toll-Like Receptor (TLR) Influences Compatibility between the Gastropod Biomphalaria glabrata, and the Digenean Trematode Schistosoma mansoni
Published in PLoS pathogens (01-03-2016)“…Schistosomiasis, a devastating disease caused by parasitic flatworms of the genus Schistosoma, affects over 260 million people worldwide especially in tropical…”
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Coordination of humoral immune factors dictates compatibility between Schistosoma mansoni and Biomphalaria glabrata
Published in eLife (09-01-2020)“…Immune factors in snails of the genus are critical for combating , the predominant cause of human intestinal schistosomiasis. Independently, many of these…”
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A metalloprotease produced by larval Schistosoma mansoni facilitates infection establishment and maintenance in the snail host by interfering with immune cell function
Published in PLoS pathogens (01-10-2018)“…Metalloproteases (MPs) have demonstrated roles in immune modulation. In some cases, these enzymes are produced by parasites to influence host immune responses…”
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Schistosomiasis from a Snail’s Perspective: Advances in Snail Immunity
Published in Trends in parasitology (01-11-2017)“…The snail’s immune response is an important determinant of schistosome infection success, acting in concert with host, parasite, and environmental factors…”
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The role of fibrinogen-related proteins in the gastropod immune response
Published in Fish & shellfish immunology (01-09-2015)“…Fibrinogen-related proteins or FREPs constitute a large family of molecules, defined by the presence of a fibrinogen-related domain (FReD). These molecules are…”
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Endogenous growth factor stimulation of hemocyte proliferation induces resistance to Schistosoma mansoni challenge in the snail host
Published in Proceedings of the National Academy of Sciences - PNAS (10-05-2016)“…Digenean trematodes are a large, complex group of parasitic flatworms that infect an incredible diversity of organisms, including humans. Larval development of…”
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The protein pheromone temptin is an attractant of the gastropod Biomphalaria glabrata
Published in Journal of Comparative Physiology (01-10-2017)“…The freshwater snail Biomphalaria glabrata has drawn much research interest by virtue of it being one of the intermediate hosts of the parasitic flatworm…”
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qPCR-based environmental monitoring of Myxobolus cerebralis and phylogenetic analysis of its tubificid hosts in Alberta, Canada
Published in Diseases of aquatic organisms (01-07-2021)“…Myxobolus cerebralis is the causative agent of whirling disease in salmonid fishes. In 2016, this invasive parasite was detected in Alberta, Canada, for the…”
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Biomphalaria glabrata Granulin Increases Resistance to Schistosoma mansoni Infection in Several Biomphalaria Species and Induces the Production of Reactive Oxygen Species by Haemocytes
Published in Genes (28-12-2019)“…Gastropod molluscs, which have co-evolved with parasitic digenean trematodes for millions of years, utilize circulating heamocytes as the primary method of…”
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Transcriptional regulation of teleost Aicda genes. Part 1 – Suppressors of promiscuous promoters
Published in Fish & shellfish immunology (01-12-2013)“…In order to better understand antibody affinity maturation in fishes we sought to identify gene regulatory elements that could drive expression of activated…”
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Corrigendum: Whole genome analysis of a schistosomiasis-transmitting freshwater snail
Published in Nature communications (23-08-2017)“…This corrects the article DOI: 10.1038/ncomms15451…”
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