Search Results - "Piket, Eliane"
-
1
The aging mouse CNS is protected by an autophagy-dependent microglia population promoted by IL-34
Published in Nature communications (09-01-2024)“…Microglia harness an unutilized health-promoting potential in age-related neurodegenerative and neuroinflammatory diseases, conditions like progressive…”
Get full text
Journal Article -
2
Hypermethylation of MIR21 in CD4+ T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up-regulation of its target genes
Published in Multiple sclerosis (01-09-2018)“…Background: Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system caused by genetic and environmental factors. DNA…”
Get full text
Journal Article -
3
Circulating miR-150 in CSF is a novel candidate biomarker for multiple sclerosis
Published in Neurology : neuroimmunology & neuroinflammation (01-06-2016)“…OBJECTIVE:To explore circulating microRNAs (miRNAs) in cell-free CSF as novel biomarkers for multiple sclerosis (MS). METHODS:Profiling of miRNAs in CSF of…”
Get full text
Journal Article -
4
Integration of small RNAs from plasma and cerebrospinal fluid for classification of multiple sclerosis
Published in Frontiers in genetics (2022)“…Multiple Sclerosis (MS) is an autoimmune, neurological disease, commonly presenting with a relapsing-remitting form, that later converts to a secondary…”
Get full text
Journal Article -
5
Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis
Published in Clinical epigenetics (30-05-2019)“…Due to limited access to brain tissue, the precise mechanisms underlying neuro-axonal dysfunction in neurological disorders such as multiple sclerosis (MS) are…”
Get full text
Journal Article -
6
Small non-coding RNAs as important players, biomarkers and therapeutic targets in multiple sclerosis: A comprehensive overview
Published in Journal of autoimmunity (01-07-2019)“…Multiple sclerosis (MS) is a leading cause of progressive disability among young adults caused by inflammation, demyelination and axonal loss in the central…”
Get full text
Journal Article -
7
Immunopathogenesis of Multiple Sclerosis : Big Roles for Small Rnas
Published 01-01-2020“…Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) and the leading cause of neurological disability in young adults…”
Get full text
Dissertation -
8
C-type lectin receptors Mcl and Mincle contro development of multiple sclerosis like neuroinflammation
Published in The Journal of clinical investigation (03-02-2020)Get full text
Journal Article -
9
Small noncoding RNA profiling across cellular and biofluid compartments and their implications for multiple sclerosis immunopathology
Published in Proceedings of the National Academy of Sciences - PNAS (27-04-2021)“…Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease affecting the central nervous system (CNS). Small noncoding RNAs (sncRNAs) and, in…”
Get full text
Journal Article -
10
C-type lectin receptors Mcl and Mincle control development of multiple sclerosis-like neuroinflammation
Published in The Journal of clinical investigation (01-02-2020)“…Pattern recognition receptors (PRRs) are crucial for responses to infections and tissue damage; however, their role in autoimmunity is less clear. Herein we…”
Get full text
Journal Article -
11
Epigenetic research in multiple sclerosis: progress, challenges, and opportunities
Published in Physiological genomics (01-09-2017)“…Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system. MS likely results from a complex interplay between…”
Get full text
Journal Article -
12
Methylome characterization of CD4+ T cells in multiple sclerosis — Establishing a role for miR-21 in autoimmune disease
Published in JOURNAL OF NEUROIMMUNOLOGY (2014)Get full text
Journal Article Conference Proceeding