Search Results - "Pike, Jason E."

Pif1 Helicase Lengthens Some Okazaki Fragment Flaps Necessitating Dna2 Nuclease/Helicase Action in the Two-nuclease Processing Pathway by Pike, Jason E., Burgers, Peter M.J., Campbell, Judith L., Bambara, Robert A.

“…We have developed a system to reconstitute all of the proposed steps of Okazaki fragment processing using purified yeast proteins and model substrates. DNA…”
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Pif1 Helicase Directs Eukaryotic Okazaki Fragments toward the Two-nuclease Cleavage Pathway for Primer Removal by Rossi, Marie L., Pike, Jason E., Wang, Wensheng, Burgers, Peter M.J., Campbell, Judith L., Bambara, Robert A.

“…Eukaryotic Okazaki fragment maturation requires complete removal of the initiating RNA primer before ligation occurs. Polymerase δ (Pol δ) extends the upstream…”
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Mechanisms by Which Bloom Protein Can Disrupt Recombination Intermediates of Okazaki Fragment Maturation by Bartos, Jeremy D., Wang, Wensheng, Pike, Jason E., Bambara, Robert A.

“…Bloom syndrome is a familial genetic disorder associated with sunlight sensitivity and a high predisposition to cancers. The mutated gene, Bloom protein (BLM),…”
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Intermediate MCAD Deficiency Associated with a Novel Mutation of the ACADM Gene: c.1052C>T by Bai, Shaochun, Stuy, Mary, Wang, Jing, Ouyang, Karen, Schumacher, Katherine, Pike, Jason E., Drendel, Holli M., Dlouhy, Stephen

“…Medium-chain acyl-CoA dehydrogenase deficiency (MCADD) is an autosomal recessive disorder that leads to a defect in fatty acid oxidation. ACADM is the only…”
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Alternative Pathway for Okazaki Fragment Processing: RESOLUTION OF FOLD-BACK FLAPS BY Pif1 HELICASE by Pike, Jason E, Henry, Ryan A, Burgers, Peter M.J, Campbell, Judith L, Bambara, Robert A

“…Two pathways have been proposed for eukaryotic Okazaki fragment RNA primer removal. Results presented here provide evidence for an alternative pathway. Primer…”
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An Alternative Pathway for Okazaki Fragment Processing by Pike, Jason E., Henry, Ryan A., Burgers, Peter M.J., Campbell, Judith L., Bambara, Robert A.

“…Two pathways have been proposed for eukaryotic Okazaki fragment RNA primer removal. Results presented here provide evidence for an alternative pathway. Primer…”
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