Search Results - "Piironen, T."

Soluble urokinase plasminogen activator receptor as a prognostic marker in men participating in prostate cancer screening by Kjellman, A., Akre, O., Gustafsson, O., Høyer‐Hansen, G., Lilja, H., Norming, U., Piironen, T., Törnblom, M.

“…  Kjellman A, Akre O, Gustafsson O, Høyer‐Hansen G, Lilja H, Norming U, Piironen T, Törnblom M (Department of Clinical Science, Intervention, and Technology;…”
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Production and Characterization of Novel Anti-Prostate-specific Antigen (PSA) Monoclonal Antibodies That Do Not Detect Internally Cleaved Lys145-Lys146 Inactive PSA by Nurmikko, Pauliina, Vaisanen, Ville, Piironen, Timo, Lindgren, Sari, Lilja, Hans, Pettersson, Kim

“…The nature of free, uncomplexed prostate-specific antigen (PSA) in the circulation is still unknown. In this study, we developed novel anti-PSA antibodies…”
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Reduced Release of Intact and Cleaved Urokinase Receptor in Stimulated Whole‐Blood Cultures from Human Immunodeficiency Virus‐1‐Infected Patients by Ostrowski, S. R., Piironen, T., Høyer‐Hansen, G., Gerstoft, J., Pedersen, B. K., Ullum, H.

“…The blood levels of the soluble forms of the urokinase receptor (suPAR) are increased in human immunodeficiency virus (HIV)‐1‐infected patients. This study…”
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The importance of human glandular kallikrein and its correlation with different prostate specific antigen serum forms in the detection of prostate carcinoma by Recker, Franz, Kwiatkowski, Maciej K., Piironen, Timo, Pettersson, Kim, Lümmen, Gerd, Wernli, Martin, Wiefelspütz, Johannes, Graber, Samuel F., Goepel, Mark, Huber, Andreas, Tscholl, Reto

“…BACKGROUND Human glandular kallikrein (hK2), the prostate specific antigen (PSA) close homologue, possesses approximately 80% structure identity with PSA. The…”
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Characterization and processing of prostate specific antigen (hK3) and human glandular kallikrein (hK2) secreted by LNCaP cells by Väisänen, V, Lövgren, J, Hellman, J, Piironen, T, Lilja, H, Pettersson, K

“…Prostate specific antigen (PSA, hK3) in serum is predominantly complexed to alpha-1-antichymotrypsin (ACT), but a minor fraction remains in a free form despite…”
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Determination and analysis of antigenic epitopes of prostate specific antigen (PSA) and human glandular kallikrein 2 (hK2) using synthetic peptides and computer modeling by Piironen, Timo, Villoutreix, Bruno O., Becker, Charlotte, Lilja, Hans, Hollingsworth, Kelly, Vihinen, Mauno, Bridon, Dominique, Qiu, Xiaoxing, Rapp, John, Dowell, Barry, Lövgren, Timo, Pettersson, Kim, Lilja, Hans

“…Prostate specific antigen (PSA) and human glandular kallikrein 2 (hK2), produced essentially by the prostate gland, are 237‐amino acid monomeric proteins, with…”
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Board life-cycle testing for effective NPI management of wireless products by Piironen, T.

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Measurement of Circulating Forms of Prostate-specific Antigen in Whole Blood Immediately after Venipuncture: Implications for Point-of-Care Testing by Piironen, Timo, Nurmi, Martti, Irjala, Kerttu, Heinonen, Olli, Lilja, Hans, Lovgren, Timo, Pettersson, Kim

“…The purpose of this study was to validate the use of whole-blood samples in the determination of circulating forms of prostate-specific antigen (PSA). Blood…”
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Summary report of the TD-3 workshop: characterization of 83 antibodies against prostate-specific antigen by Stenman, U H, Paus, E, Allard, W J, Andersson, I, Andrès, C, Barnett, T R, Becker, C, Belenky, A, Bellanger, L, Pellegrino, C M, Børmer, O P, Davis, G, Dowell, B, Grauer, L S, Jette, D C, Karlsson, B, Kreutz, F T, van der Kwast, T M, Lauren, L, Leinimaa, M, Leinonen, J, Lilja, H, Linton, H J, Nap, M, Hilgers, J

“…Twelve research groups participated in the ISOBM TD-3 Workshop in which the reactivity and specificity of 83 antibodies against prostate-specific antigen (PSA)…”
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Enhanced expression of prostate-specific antigen in the transition zone of the prostate. A characterization following prostatectomy for benign hyperplasia by Recker, F, Kwiatkowski, M K, Pettersson, K, Piironen, T, Lümmen, G, Huber, A, Tscholl, R

“…To determine whether the serum levels of total prostate-specific antigen (t-PSA), free PSA (f-PSA) and PSA complexed to alpha 1-antichymotrypsin (PSA-ACT)…”
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Epitope mapping of human prostate specific antigen and glandular kallikrein expressed in insect cells by Rajakoski, K, Piironen, T, Pettersson, K, Lövgren, J, Karp, M

“…Two human prostate gland proteases were expressed in insect cells using recombinant baculovirus expression system. Prostate specific antigen (PSA) is an…”
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Free‐to‐total prostate‐specific antigen (PSA) ratio improves the specificity for detecting prostate cancer in patients with prostatism and intermediate PSA levels by RECKER, F, KWIATKOWSKI, M. K, PIIRONEN, T, PETTERSSON, K, GOEPEL, M, TSCHOLL, R

“…Objective  To investigate the clinical significance of the free‐to‐total prostate‐specific antigen (PSA) ratio in improving the specificity of PSA measurement…”
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Reactivity of anti-PSA monoclonal antibodies with recombinant human kallikrein-2 by Leinonen, J, Leinimaa, M, Zhang, W M, Piironen, T, Pettersson, K, Lilja, H, Dowell, B, Stenman, U H

“…Seventy-nine monoclonal antibodies submitted to the ISOBM TD-3 PSA Workshop were tested for their reactivity with recombinant human kallikrein-2 (rhK2). A…”
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Reproducibility and accuracy of measurements of free and total prostate-specific antigen in serum vs plasma after long-term storage at -20 degrees C by Ulmert, David, Becker, Charlotte, Nilsson, Jan-Ake, Piironen, Timo, Björk, Thomas, Hugosson, Jonas, Berglund, Göran, Lilja, Hans

“…Long-term frozen storage may alter the results of prostate-specific antigen (PSA) measurements, mainly because of degradation of free PSA (fPSA) in vitro. We…”
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Soluble urokinase plasminogen activator receptor as a prognostic marker in men participating in prostate cancer screening: suPAR: a prognostic marker for overall survival by Kjellman, A., Akre, O., Gustafsson, O., Høyer-Hansen, G., Lilja, H., Norming, U., Piironen, T., Törnblom, M.

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Specific Immunoassays for Detection of Intact and Cleaved Forms of the Urokinase Receptor by Piironen, Timo, Laursen, Birgitte, Pass, Jesper, List, Karin, Gardsvoll, Henrik, Ploug, Michael, Dano, Keld, Hoyer-Hansen, Gunilla

“…The cell surface receptor (uPAR) for urokinase plasminogen activator (uPA) is a strong prognostic marker in several types of cancer. uPA cleaves the…”
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Prognostic Significance of Soluble Urokinase Plasminogen Activator Receptor in Serum and Cytosol of Tumor Tissue from Patients with Primary Breast Cancer by RIISBRO, Rikke, CHRISTENSEN, Ib J, HARRIS, Adrian L, PIIRONEN, Timo, GREENALL, Michael, LARSEN, Berthe, STEPHENS, Ross W, CHENG HAN, HØYER-HANSEN, Gunilla, SMITH, Kenneth, BRIINNER, Nils

“…Purpose: The aim of the study was to evaluate the prognostic value of soluble urokinase plasminogen activator receptor (suPAR) in preoperatively obtained sera…”
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High Plasma Levels of Intact and Cleaved Soluble Urokinase Receptor Reflect Immune Activation and Are Independent Predictors of Mortality in HIV-1-Infected Patients by Ostrowski, Sisse Rye, Piironen, Timo, Høyer-Hansen, Gunilla, Gerstoft, Jan, Pedersen, Bente Klarlund, Ullum, Henrik

“…BACKGROUND:High blood levels of soluble urokinase receptor (suPAR) measured by enzyme-linked immunoassay (ELISA) (bulk measurement of 3-domain and 2-domain…”
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Clinical value of human glandular kallikrein 2 and free and total prostate-specific antigen in serum from a population of men with prostate-specific antigen levels 3.0 ng/mL or greater by Becker, Charlotte, Piironen, Timo, Pettersson, Kim, Hugosson, Jonas, Lilja, Hans

“…Objectives. To investigate the clinical value of human glandular kallikrein 2 (hK2) compared with free (f) and total (t) prostate-specific antigen (PSA) in the…”
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Human glandular kallikrein 2 levels in serum for discrimination of pathologically organ-confined from locally-advanced prostate cancer in total PSA-levels below 10 ng/ml by Haese, Alexander, Graefen, Markus, Steuber, Thomas, Becker, Charlotte, Pettersson, Kim, Piironen, Timo, Noldus, Joachim, Huland, Hartwig, Lilja, Hans

“…Background We measured serum levels of human glandular kallikrein 2 (hK2) in patients treated with radical retropubic prostatectomy (rrP) for clinically…”
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