Search Results - "Pihlap, Maire"

MicroRNA-146a alleviates chronic skin inflammation in atopic dermatitis through suppression of innate immune responses in keratinocytes by Rebane, Ana, PhD, Runnel, Toomas, MSc, Aab, Alar, MSc, Maslovskaja, Julia, MSc, Rückert, Beate, BSc, Zimmermann, Maya, PhD, Plaas, Mario, PhD, Kärner, Jaanika, MSc, Treis, Angela, MSc, Pihlap, Maire, BSc, Haljasorg, Uku, MSc, Hermann, Helen, BSc, Nagy, Nikoletta, MD, PhD, Kemeny, Lajos, MD, Erm, Triin, MD, Kingo, Külli, MD, PhD, Li, Mei, PhD, Boldin, Mark P., PhD, Akdis, Cezmi A., MD

“…Background Chronic skin inflammation in atopic dermatitis (AD) is associated with elevated expression of proinflammatory genes and activation of innate immune…”
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Signs of innate immune activation and premature immunosenescence in psoriasis patients by Šahmatova, Liisi, Sügis, Elena, Šunina, Marina, Hermann, Helen, Prans, Ele, Pihlap, Maire, Abram, Kristi, Rebane, Ana, Peterson, Hedi, Peterson, Pärt, Kingo, Külli, Kisand, Kai

“…Psoriasis is a chronic inflammatory disease that affects skin and is associated with systemic inflammation and many serious comorbidities ranging from…”
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Mechanisms of IFN-γ–induced apoptosis of human skin keratinocytes in patients with atopic dermatitis by Rebane, Ana, PhD, Zimmermann, Maya, PhD, Aab, Alar, MSc, Baurecht, Hansjörg, MSc, Koreck, Andrea, MD, Karelson, Maire, MD, Abram, Kristi, MD, Metsalu, Tauno, MSc, Pihlap, Maire, BSc, Meyer, Norbert, MD, Fölster-Holst, Regina, MD, Nagy, Nikoletta, MD, PhD, Kemeny, Lajos, MD, Kingo, Külli, MD, PhD, Vilo, Jaak, PhD, Illig, Thomas, MD, Akdis, Mübeccel, MD, PhD, Franke, Andre, PhD, Novak, Natalija, MD, Weidinger, Stephan, MD, Akdis, Cezmi A., MD

“…Background Enhanced apoptosis of keratinocytes is the main cause of eczema and spongiosis in patients with the common inflammatory skin disease atopic…”
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Lymphoid Stress Surveillance Response Contributes to Vitiligo Pathogenesis by Raam, Liisi, Kaleviste, Epp, Šunina, Marina, Vaher, Helen, Saare, Mario, Prans, Ele, Pihlap, Maire, Abram, Kristi, Karelson, Maire, Peterson, Pärt, Rebane, Ana, Kisand, Kai, Kingo, Külli

“…Vitiligo is a chronic multifactorial depigmentation disorder characterized by the destruction and functional loss of melanocytes. Although a direct cytotoxic T…”
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Autoantibody Repertoire in APECED Patients Targets Two Distinct Subgroups of Proteins by Fishman, Dmytro, Kisand, Kai, Hertel, Christina, Rothe, Mike, Remm, Anu, Pihlap, Maire, Adler, Priit, Vilo, Jaak, Peet, Aleksandr, Meloni, Antonella, Podkrajsek, Katarina Trebusak, Battelino, Tadej, Bruserud, Øyvind, Wolff, Anette S B, Husebye, Eystein S, Kluger, Nicolas, Krohn, Kai, Ranki, Annamari, Peterson, Hedi, Hayday, Adrian, Peterson, Pärt

“…High titer autoantibodies produced by B lymphocytes are clinically important features of many common autoimmune diseases. APECED patients with deficient…”
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DNA methylation signatures of the AIRE promoter in thymic epithelial cells, thymomas and normal tissues by Kont, Vivian, Murumägi, Astrid, Tykocinski, Lars-Oliver, Kinkel, Sarah A., Webster, Kylie E., Kisand, Kai, Tserel, Liina, Pihlap, Maire, Ströbel, Philipp, Scott, Hamish S., Marx, Alexander, Kyewski, Bruno, Peterson, Pärt

“…► AIRE is a key molecule in thymic tolerance to peripheral tissue-specific antigens. ► We studied the CpG methylation and histone modifications in AIRE gene in…”
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SP140L, an Evolutionarily Recent Member of the SP100 Family, Is an Autoantigen in Primary Biliary Cirrhosis by Toots, Urve, Salupere, Riina, Musco, Giovanna, Uibo, Raivo, Peterson, Pärt, Kisand, Kai, Remm, Anu, Pihlap, Maire, Zucchelli, Chiara, Panarina, Marina, Venta, Rainis, Hämarik, Uku, Saare, Mario, Möll, Kaidi

“…The SP100 family members comprise a set of closely related genes on chromosome 2q37.1. The widely expressed SP100 and the leukocyte-specific proteins SP110 and…”
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MicroRNA Expression Profiles of Human Blood Monocyte-derived Dendritic Cells and Macrophages Reveal miR-511 as Putative Positive Regulator of Toll-like Receptor 4 by Tserel, Liina, Runnel, Toomas, Kisand, Kai, Pihlap, Maire, Bakhoff, Lairi, Kolde, Raivo, Peterson, Hedi, Vilo, Jaak, Peterson, Pärt, Rebane, Ana

“…Dendritic cells (DCs) and macrophages (MFs) are important multifunctional immune cells. Like other cell types, they express hundreds of different microRNAs…”
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A highly conserved NF‐κB‐responsive enhancer is critical for thymic expression of Aire in mice by Haljasorg, Uku, Bichele, Rudolf, Saare, Mario, Guha, Mithu, Maslovskaja, Julia, Kõnd, Karin, Remm, Anu, Pihlap, Maire, Tomson, Laura, Kisand, Kai, Laan, Martti, Peterson, Pärt

“…Autoimmune regulator (Aire) has a unique expression pattern in thymic medullary epithelial cells (mTECs), in which it plays a critical role in the activation…”
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MicroRNA-155 is Dysregulated in the Skin of Patients with Vitiligo and Inhibits Melanogenesis-associated Genes in Melanocytes and Keratinocytes by Šahmatova, Liisi, Tankov, Stoyan, Prans, Ele, Aab, Alar, Hermann, Helen, Reemann, Paula, Pihlap, Maire, Karelson, Maire, Abram, Kristi, Kisand, Kai, Kingo, Külli, Rebane, Ana

“…Little is known about the functions of microRNAs (miRNAs) in skin pigmentation disorders. The aim of this study was to investigate the expression and potential…”
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A highly conserved NF-[kappa]B-responsive enhancer is critical for thymic expression of Aire in mice by Haljasorg, Uku, Bichele, Rudolf, Saare, Mario, Guha, Mithu, Maslovskaja, Julia, Kond, Karin, Remm, Anu, Pihlap, Maire, Tomson, Laura, Kisand, Kai, Laan, Martti, Peterson, Pärt

“…Autoimmune regulator (Aire) has a unique expression pattern in thymic medullary epithelial cells (mTECs), in which it plays a critical role in the activation…”
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IL‐6‐specific autoantibodies among APECED and thymoma patients by Kärner, Jaanika, Pihlap, Maire, Ranki, Annamari, Krohn, Kai, Trebusak Podkrajsek, Katarina, Bratanic, Nina, Battelino, Tadej, Willcox, Nick, Peterson, Pärt, Kisand, Kai

“…Introduction Both autoimmune polyendocrinopathy‐candidiasis‐ectodermal dystrophy (APECED) and the rare thymoma patients with chronic mucocutaneous candidiasis…”
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Mechanisms of IFN-[gamma]-induced apoptosis of human skin keratinocytes in patients with atopic dermatitis by Rebane, Ana, Zimmermann, Maya, Aab, Alar, Baurecht, Hansjörg, Koreck, Andrea, Karelson, Maire, Abram, Kristi, Metsalu, Tauno, Pihlap, Maire, Meyer, Norbert, Fölster-Holst, Regina, Nagy, Nikoletta, Kemeny, Lajos, Kingo, Külli, Vilo, Jaak, Illig, Thomas, Akdis, Mübeccel, Franke, Andre, Novak, Natalija, Weidinger, Stephan, Akdis, Cezmi A

“…Background Enhanced apoptosis of keratinocytes is the main cause of eczema and spongiosis in patients with the common inflammatory skin disease atopic…”
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