Search Results - "Pihlajamäki, Jussi"
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Mucosal-associated invariant T cell alterations during the development of human type 1 diabetes
Published in Diabetologia (01-11-2020)“…Aims/hypothesis Mucosal-associated invariant T (MAIT) cells are innate-like T cells that recognise derivatives of bacterial riboflavin metabolites presented by…”
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FADS1 rs174550 genotype and high linoleic acid diet modify plasma PUFA phospholipids in a dietary intervention study
Published in European journal of nutrition (01-03-2022)“…Introduction Fatty acid desaturase 1 ( FADS1 ) gene encodes for delta-5 desaturase enzyme which is needed in conversion of linoleic acid (LA) to arachidonic…”
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3
Effectiveness of workplace choice architecture modification for healthy eating and daily physical activity
Published in BMC public health (01-04-2024)“…Modifying the choice architecture of behavioural contexts can facilitate health behaviour change, but existing evidence builds mostly on small-scale…”
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The Effects of Acceptance and Commitment Therapy (ACT) Intervention on Inflammation and Stress Biomarkers: a Randomized Controlled Trial
Published in International journal of behavioral medicine (01-10-2020)“…Background Psychological processes can be manifested in physiological health. We investigated whether acceptance and commitment therapy (ACT), targeted on…”
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Thyroid Hormone-Related Regulation of Gene Expression in Human Fatty Liver
Published in The journal of clinical endocrinology and metabolism (01-09-2009)“…Context: Fatty liver is an important complication of obesity; however, regulatory mechanisms mediating altered gene expression patterns have not been…”
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Multiple abnormalities in glucose and energy metabolism and coordinated changes in levels of adiponectin, cytokines, and adhesion molecules in subjects with metabolic syndrome
Published in Circulation (New York, N.Y.) (21-12-2004)“…Detailed metabolic defects in glucose and energy metabolism and abnormalities in a variety of cardiovascular risk factors are largely unknown in subjects with…”
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Correction to: Small Intestinal Length Associates with Serum Triglycerides Before and After LRYGB
Published in Obesity surgery (2022)Get full text
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Comparative Nontargeted Profiling of Metabolic Changes in Tissues and Biofluids in High-Fat Diet-Fed Ossabaw Pig
Published in Journal of proteome research (06-09-2013)“…Typical clinical biomarker analyses on urine and plasma samples from human dietary interventions do not provide adequate information about diet-induced…”
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The C-174G Promoter Polymorphism of the IL-6 Gene Affects Energy Expenditure and Insulin Sensitivity
Published in Diabetes (New York, N.Y.) (01-02-2003)“…The C-174G Promoter Polymorphism of the IL-6 Gene Affects Energy Expenditure and Insulin Sensitivity Agata Kubaszek 1 , Jussi Pihlajamäki 1 , Kari Punnonen 2 ,…”
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10
Expression of the Splicing Factor Gene SFRS10 Is Reduced in Human Obesity and Contributes to Enhanced Lipogenesis
Published in Cell metabolism (03-08-2011)“…Alternative mRNA splicing provides transcript diversity and may contribute to human disease. We demonstrate that expression of several genes regulating RNA…”
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Cold-stimulated brown adipose tissue activation is related to changes in serum metabolites relevant to NAD+ metabolism in humans
Published in Cell reports (Cambridge) (01-09-2023)“…Cold-induced brown adipose tissue (BAT) activation is considered to improve metabolic health. In murine BAT, cold increases the fundamental molecule for…”
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Enhanced Eating Competence Is Associated with Improved Diet Quality and Cardiometabolic Profile in Finnish Adults with Increased Risk of Type 2 Diabetes
Published in Nutrients (11-11-2021)“…Eating competence (EC) is characterized by positive attitudes towards food and eating, having regular meals, eating a variety of foods, and internally…”
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Association of fatty liver disease with mortality outcomes in an Eastern Finland male cohort
Published in BMJ open gastroenterology (01-01-2019)“…ObjectiveFatty liver disease (FLD) has been associated with extrahepatic morbidity outcomes. However, reports on the association of FLD, assessed using fatty…”
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Visfatin Is an Adipokine, But It Is Not Regulated by Thiazolidinediones
Published in The journal of clinical endocrinology and metabolism (01-03-2006)“…Context: Visfatin was recently reported to be expressed in human adipose tissue and to exert insulin-mimicking effects. Objective: The objective of this study…”
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15
Probiotics modulated gut microbiota suppresses hepatocellular carcinoma growth in mice
Published in Proceedings of the National Academy of Sciences - PNAS (01-03-2016)“…The beneficial roles of probiotics in lowering the gastrointestinal inflammation and preventing colorectal cancer have been frequently demonstrated, but their…”
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Single-Nucleotide Polymorphism rs7754840 of CDKAL1 Is Associated with Impaired Insulin Secretion in Nondiabetic Offspring of Type 2 Diabetic Subjects and in a Large Sample of Men with Normal Glucose Tolerance
Published in The journal of clinical endocrinology and metabolism (01-05-2008)“…Context: CDKAL1 is a recently discovered susceptibility gene for type 2 diabetes. Objective: Our objective was to investigate the impact of rs7754840 of CDKAL1…”
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Protein Phosphatase 1 Regulatory Subunit 3 Beta rs4240624 Genotype Is Associated With Gallstones and With Significant Changes in Bile Lipidome
Published in Gastro hep advances (2024)“…Gallstone disease (GSD) associates with significant morbidity and mortality. Decreased secretion of bile acids has been suggested as a driving factor for GSD…”
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Correction to: Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes
Published in Genome medicine (30-08-2021)Get full text
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The K121Q Polymorphism of the PC-1 Gene Is Associated With Insulin Resistance but not With Dyslipidemia
Published in Diabetes care (01-02-2003)“…The K121Q Polymorphism of the PC-1 Gene Is Associated With Insulin Resistance but not With Dyslipidemia Agata Kubaszek , MD , Jussi Pihlajamäki , MD , Pauli…”
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Comparison of Communication Channels for Large-Scale Type 2 Diabetes Risk Screening and Intervention Recruitment: Empirical Study
Published in JMIR diabetes (09-09-2021)“…Background Clinical trials have shown that type 2 diabetes (T2D) is preventable through lifestyle interventions targeting high-risk people. Nevertheless,…”
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