Search Results - "Pihl, Anne Finne"

High-Titer Hepatitis C Virus Production in a Scalable Single-Use High Cell Density Bioreactor by Offersgaard, Anna, Duarte Hernandez, Carlos Rene, Pihl, Anne Finne, Venkatesan, Nandini Prabhakar, Krarup, Henrik, Lin, Xiangliang, Reichl, Udo, Bukh, Jens, Genzel, Yvonne, Gottwein, Judith Margarete

“…Hepatitis C virus (HCV) infections pose a major public health burden due to high chronicity rates and associated morbidity and mortality. A vaccine protecting…”
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Inactivated genotype 1a, 2a and 3a HCV vaccine candidates induced broadly neutralising antibodies in mice by Alzua, Garazi Pena, Pihl, Anne Finne, Offersgaard, Anna, Duarte Hernandez, Carlos Rene, Duan, Zhe, Feng, Shan, Fahnøe, Ulrik, Sølund, Christina, Weis, Nina, Law, Mansun, Prentoe, Jannick C, Christensen, Jan Pravsgaard, Bukh, Jens, Gottwein, Judith Margarete

“…A prophylactic vaccine is needed to control the HCV epidemic, with genotypes 1-3 causing >80% of worldwide infections. Vaccine development is hampered by HCV…”
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Evolutionary Pathways to Persistence of Highly Fit and Resistant Hepatitis C Virus Protease Inhibitor Escape Variants by Jensen, Sanne Brun, Fahnøe, Ulrik, Pham, Long V., Serre, Stéphanie Brigitte Nelly, Tang, Qi, Ghanem, Lubna, Pedersen, Martin Schou, Ramirez, Santseharay, Humes, Daryl, Pihl, Anne Finne, Filskov, Jonathan, Sølund, Christina Søhoel, Dietz, Julia, Fourati, Slim, Pawlotsky, Jean‐Michel, Sarrazin, Christoph, Weis, Nina, Schønning, Kristian, Krarup, Henrik, Bukh, Jens, Gottwein, Judith Margarete

“…Protease inhibitors (PIs) are important components of treatment regimens for patients with chronic hepatitis C virus (HCV) infection. However, emergence and…”
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Specific Antibodies Induced by Immunization with Hepatitis B Virus-Like Particles Carrying Hepatitis C Virus Envelope Glycoprotein 2 Epitopes Show Differential Neutralization Efficiency by Czarnota, Anna, Offersgaard, Anna, Pihl, Anne Finne, Prentoe, Jannick, Bukh, Jens, Gottwein, Judith Margarete, Bieńkowska-Szewczyk, Krystyna, Grzyb, Katarzyna

“…Hepatitis C virus (HCV) infection with associated chronic liver diseases is a major health problem worldwide. Here, we designed hepatitis B virus (HBV) small…”
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SARS-CoV-2 Production in a Scalable High Cell Density Bioreactor by Offersgaard, Anna, Duarte Hernandez, Carlos Rene, Pihl, Anne Finne, Costa, Rui, Venkatesan, Nandini Prabhakar, Lin, Xiangliang, Van Pham, Long, Feng, Shan, Fahnøe, Ulrik, Scheel, Troels Kasper Høyer, Ramirez, Santseharay, Reichl, Udo, Bukh, Jens, Genzel, Yvonne, Gottwein, Judith Margarete

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has demonstrated the value of pursuing different vaccine strategies. Vaccines based…”
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An inactivated SARS-CoV-2 vaccine induced cross-neutralizing persisting antibodies and protected against challenge in small animals by Offersgaard, Anna, Duarte Hernandez, Carlos Rene, Feng, Shan, Marichal-Gallardo, Pavel, Holmbeck, Kenn, Pihl, Anne Finne, Fernandez-Antunez, Carlota, Alzua, Garazi Peña, Hartmann, Katrine Top, Pham, Long V., Zhou, Yuyong, Gammeltoft, Karen Anbro, Fahnøe, Ulrik, Schneider, Uffe Vest, Pedersen, Gabriel Kristian, Jensen, Henrik Elvang, Christensen, Jan Pravsgaard, Ramirez, Santseharay, Bukh, Jens, Gottwein, Judith Margarete

“…Vaccines have relieved the public health burden of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and globally inactivated vaccines are most…”
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Inactivated whole hepatitis C virus vaccine employing a licensed adjuvant elicits cross-genotype neutralizing antibodies in mice by Pihl, Anne Finne, Feng, Shan, Offersgaard, Anna, Alzua, Garazi Peña, Augestad, Elias Honerød, Mathiesen, Christian Kjaerulff, Jensen, Tanja Bertelsen, Krarup, Henrik, Law, Mansun, Prentoe, Jannick, Christensen, Jan Pravsgaard, Bukh, Jens, Gottwein, Judith Margarete

“…A prophylactic vaccine is required to eliminate HCV as a global public health threat. We developed whole virus inactivated HCV vaccine candidates employing a…”
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An inactivated SARS-CoV-2 vaccine induced cross-neutralising persisting antibodies and protected upon challenge in small animals by Offersgaard, Anna, Duarte Hernandez, Carlos Rene, Feng, Shan, Marichal-Gallardo, Pavel, Holmbeck, Kenn, Pihl, Anne Finne, Fernandez-Antunez, Carlota, Alzua, Garazi Peña, Hartmann, Katrine Top, Pham, Long V., Zhou, Yuyong, Gammeltoft, Karen Anbro, Fahnøe, Ulrik, Schneider, Uffe Vest, Pedersen, Gabriel Kristian, Jensen, Henrik Elvang, Christensen, Jan Pravsgaard, Ramirez, Santseharay, Bukh, Jens, Gottwein, Judith Margarete

“…Vaccines have relieved the public health burden of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and globally inactivated vaccines are most…”
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Identification of Novel Determinants of Neutralization Epitope Shielding for Hepatitis C Virus in Vitro by Garazi Peña Alzua, Anne Finne Pihl, Anna Falden Offersgaard, Rodrigo Velázquez-Moctezuma, Elias Honeroed Augestad, Ulrik Fahnøe, Christian Kjaerulff Mathiesen, Mansun Law, Jannick Prentoe, Jens Bukh, Judith Margarete Gottwein

“…Epitope shielding is suggested as an important mechanism mediating the escape of hepatitis C virus (HCV) from host-neutralizing antibodies (nAb). [...]…”
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