Search Results - "Pigozzi, Simona"
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Factors affecting immunoreactivity in long-term storage of formalin-fixed paraffin-embedded tissue sections
Published in Histochemistry and cell biology (01-07-2015)“…Antigen decay in archival formalin-fixed paraffin-embedded (FFPE) tissue sections for immunohistochemistry is a well-known phenomenon which may have…”
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Methods for restoration of ki67 antigenicity in aged paraffin tissue blocks
Published in Histochemistry and cell biology (01-08-2021)“…Pathology archives are a treasure trove of paraffin embedded tissue spanning many years and covering a wide variety of tissues and diseases. The possibility of…”
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The synergism of SMC1A cohesin gene silencing and bevacizumab against colorectal cancer
Published in Journal of experimental & clinical cancer research (16-02-2024)“…SMC1A is a subunit of the cohesin complex that participates in many DNA- and chromosome-related biological processes. Previous studies have established that…”
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Chronic lymphocytic leukemia cells impair osteoblastogenesis and promote osteoclastogenesis: role of TNFα, IL-6 and IL-11 cytokines
Published in Haematologica (Roma) (01-10-2021)“…Bone skeletal alterations are no longer considered a rare event in chronic lymphocytic leukemia (CLL), especially at more advanced stages of the disease. This…”
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A Never Ending Journey: Ectopic Thyroid
Published in International journal of surgical pathology (01-05-2017)Get full text
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The Seeds of Doubt: Finding Seeds in Intriguing Places
Published in Frontiers in medicine (14-04-2021)“…Seeds may be found in gastrointestinal tissue samples, and their multifaceted appearance may be challenging. The aim is to report a rough incidence of…”
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Immunohistochemistry on old archival paraffin blocks: is there an expiry date?
Published in Journal of clinical pathology (01-11-2017)“…Few studies have focused on antigen preservation in formalin-fixed and paraffin-embedded (FFPE) tissue in old archival material and additional studies are…”
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Be bold, start cold! cold formalin fixation of colorectal cancer specimens granted superior DNA and RNA quality for downstream molecular analysis
Published in Histochemistry and cell biology (01-12-2024)“…The use of cold formalin fixation (CFF; i.e., fixating tissue samples with 4 °C precooled formalin) recently attracted further attention owing to its putative…”
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Synchronous and metachronous primary colorectal cancers with concordant and discordant mismatch repair status
Published in Human pathology (01-11-2023)“…Multiple primary colorectal carcinomas (CRCs) synchronous, when detected approximately at the same time, or metachronous, when a significant amount of time has…”
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Impact of formalin fixation on mismatch repair protein evaluation by immunohistochemistry
Published in Virchows Archiv : an international journal of pathology (01-11-2023)“…Mismatch repair/microsatellite instability (MMR/MSI) status in colorectal cancer (CRC) has become fundamental as a diagnostic, prognostic, and predictive…”
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BRAFV600E immunohistochemistry can reliably substitute BRAF molecular testing in the Lynch syndrome screening algorithm in colorectal cancer
Published in Histopathology (01-04-2024)“…Aims The Lynch syndrome (LS) screening algorithm requires BRAF testing as a fundamental step to distinguish sporadic from LS‐associated colorectal carcinomas…”
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BRAF V600E immunohistochemistry can reliably substitute BRAF molecular testing in the Lynch syndrome screening algorithm in colorectal cancer
Published in Histopathology (01-04-2024)“…The Lynch syndrome (LS) screening algorithm requires BRAF testing as a fundamental step to distinguish sporadic from LS-associated colorectal carcinomas (CRC)…”
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Ultra‐hyper‐fractionated radiotherapy for high‐grade gliomas
Published in Journal of neuroscience research (01-12-2021)“…High‐grade gliomas (HGGs; WHO grades III and IV) are invariably lethal brain tumors. Low‐dose hyper‐radiosensitivity (HRS) of HGG is a well‐established…”
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HLA-G as a prognostic marker in stage II/III colorectal cancer: not quite there yet
Published in Histochemistry and cell biology (01-12-2022)“…Identifying innovative molecules involved in the tumor immune escape process could help refine the survival stratification of colorectal cancer (CRC) patients…”
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Extra-prostatic extension grading system: correlation with MRI features and integration of capsular enhancement sign for "enhanced" detection of T3a lesions
Published in British journal of radiology (07-05-2024)“…This study aims to confirm the diagnostic accuracy of extra-prostatic extension (EPE) grading system and to explore the predictive capabilities of the prostate…”
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HLA-G expression in gastric carcinoma: clinicopathological correlations and prognostic impact
Published in Virchows Archiv : an international journal of pathology (01-10-2018)“…To analyze expression of human leukocyte antigen-G (HLA-G) in gastric adenocarcinoma and correlate its expression with histological and clinical variables. A…”
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Increased Arginase1 expression in tumor microenvironment promotes mammary carcinogenesis via multiple mechanisms
Published in Carcinogenesis (New York) (31-12-2020)“…Abstract Arginine metabolism plays a significant role in regulating cell function, affecting tumor growth and metastatization. To study the effect of the…”
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Section detachment in immunohistochemistry: causes, troubleshooting, and problem-solving
Published in Histochemistry and cell biology (01-07-2017)“…Section detachment in immunohistochemistry (IHC) is a common phenomenon, increasing times and costs of diagnosis and research. However, it has poorly been…”
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Coping with formalin banning in pathology: under vacuum long-term tissue storage with no added formalin
Published in Histochemistry and cell biology (01-06-2019)“…Formalin is toxic and has recently been classified as carcinogenic leading to a proposed European formalin ban. But, the pathology use of formalin has however…”
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Twenty years of gastroenteropancreatic neuroendocrine tumors: is reclassification worthwhile and feasible?
Published in Endocrine (01-07-2016)“…Gastroenteropancreatic (GEP) neuroendocrine tumors (NETs) are rare neoplasms with heterogeneous clinical behavior and potential long-term survival. In…”
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