Search Results - "Pigino, Gustavo F"

Protein Misfolding, Signaling Abnormalities and Altered Fast Axonal Transport: Implications for Alzheimer and Prion Diseases by Zamponi, Emiliano, Pigino, Gustavo F

“…Histopathological studies revealed that progressive neuropathies including Alzheimer, and Prion diseases among others, include accumulations of misfolded…”
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Inhibition of fast axonal transport by pathogenic SOD1 involves activation of p38 MAP kinase by Morfini, Gerardo A, Bosco, Daryl A, Brown, Hannah, Gatto, Rodolfo, Kaminska, Agnieszka, Song, Yuyu, Molla, Linda, Baker, Lisa, Marangoni, M Natalia, Berth, Sarah, Tavassoli, Ehsan, Bagnato, Carolina, Tiwari, Ashutosh, Hayward, Lawrence J, Pigino, Gustavo F, Watterson, D Martin, Huang, Chun-Fang, Banker, Gary, Brown, Jr, Robert H, Brady, Scott T

“…Dying-back degeneration of motor neuron axons represents an established feature of familial amyotrophic lateral sclerosis (FALS) associated with superoxide…”
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Prion protein inhibits fast axonal transport through a mechanism involving casein kinase 2 by Zamponi, Emiliano, Buratti, Fiamma, Cataldi, Gabriel, Caicedo, Hector Hugo, Song, Yuyu, Jungbauer, Lisa M, LaDu, Mary J, Bisbal, Mariano, Lorenzo, Alfredo, Ma, Jiyan, Helguera, Pablo R, Morfini, Gerardo A, Brady, Scott T, Pigino, Gustavo F

“…Prion diseases include a number of progressive neuropathies involving conformational changes in cellular prion protein (PrPc) that may be fatal sporadic,…”
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Axonal degeneration in Alzheimer's disease: When signaling abnormalities meet the axonal transport system by Kanaan, Nicholas M., Pigino, Gustavo F., Brady, Scott T., Lazarov, Orly, Binder, Lester I., Morfini, Gerardo A.

“…Alzheimer's disease (AD) is characterized by progressive, age-dependent degeneration of neurons in the central nervous system. A large body of evidence…”
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Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases by Kanaan, Nicholas M, Morfini, Gerardo A, LaPointe, Nichole E, Pigino, Gustavo F, Patterson, Kristina R, Song, Yuyu, Andreadis, Athena, Fu, Yifan, Brady, Scott T, Binder, Lester I

“…Aggregated filamentous forms of hyperphosphorylated tau (a microtubule-associated protein) represent pathological hallmarks of Alzheimer's disease (AD) and…”
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APP/Go protein Gβγ-complex signaling mediates Aβ degeneration and cognitive impairment in Alzheimer's disease models by Bignante, Elena Anahi, Ponce, Nicolás Eric, Heredia, Florencia, Musso, Juliana, Krawczyk, María C., Millán, Julieta, Pigino, Gustavo F., Inestrosa, Nibaldo C., Boccia, Mariano M., Lorenzo, Alfredo

“…Deposition of amyloid-β (Aβ), the proteolytic product of the amyloid precursor protein (APP), might cause neurodegeneration and cognitive decline in…”
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Axonal degeneration in Alzheimer's disease: When signaling abnormalities meet the axonal transport system: Axonal degeneration by KANAAN, Nicholas M, PIGINO, Gustavo F, BRADY, Scott T, LAZAROV, Orly, BINDER, Lester I, MORFINI, Gerardo A

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