Search Results - "Pietsch, Thorsten"
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A matched-pair analysis on survival and response rates between German and non-German cancer patients treated at a Comprehensive Cancer Center
Published in BMC cancer (30-10-2019)“…Research shows disparities in cancer outcomes by ethnicity or socio-economic status. Therefore, it is the aim of our study to perform a matched-pair analysis…”
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Treatment options in childhood pontine gliomas
Published in Journal of neuro-oncology (01-09-2006)“…Pontine gliomas are the subgroup of brainstem gliomas with the worst prognosis. Controversial treatment approaches are discussed. Data of children with pontine…”
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5-Aminolevulinic Acid-derived Tumor Fluorescence: The Diagnostic Accuracy of Visible Fluorescence Qualities as Corroborated by Spectrometry and Histology and Postoperative Imaging
Published in Neurosurgery (01-03-2014)“…BACKGROUND:5-Aminolevulinic acid is used for fluorescence-guided resections. During resection, different macroscopic fluorescence qualities (“strong,” “weak”)…”
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Five-aminolevulinic acid for fluorescence-guided resection of recurrent malignant gliomas: a phase ii study
Published in Neurosurgery (01-12-2009)“…To assess the feasibility of 5-aminolevulinic acid (5-ALA) fluorescence guidance for resection of recurrent malignant brain tumors. In a multicenter…”
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High-dose Methotrexate Prior to Simultaneous Radiochemotherapy in Children with Malignant High-grade Gliomas
Published in Anticancer research (01-05-2005)“…Background: Preradiation chemotherapy including methotrexate (MTX) was effective in children with completely resected high-grade gliomas (HGG). The specific…”
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MEDB-38. Significance of CSF cytology and neurologic deterioration in relapsed medulloblastomas in the German HIT-REZ-97/-2005 Studies and the HIT-REZ-Register
Published in Neuro-oncology (Charlottesville, Va.) (03-06-2022)“…Abstract BACKGROUND: Follow-up examinations are an essential part of the aftercare of patients with brain tumours. We investigated survival in relation to…”
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Assessing CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide data in the biomarker cohort of the NOA-04 trial
Published in Neuro-oncology (Charlottesville, Va.) (01-12-2014)“…Molecular biomarkers including isocitrate dehydrogenase 1 or 2 (IDH1/2) mutation, 1p/19q codeletion, and O(6)-methylguanine-DNA-methyltransferase (MGMT)…”
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ACTR-64. OBJECTIVE RESPONSES TO CHEMOTHERAPY IN RECURRENT GLIOMA DO NOT PREDICT BETTER SURVIVAL: A PROSPECTIVE ANALYSIS FROM THE GERMAN GLIOMA NETWORK
Published in Neuro-oncology (Charlottesville, Va.) (05-11-2018)“…Abstract Outside of clinical trials, the occurrence of objective responses (OR) to chemotherapy in patients with recurrent gliomas is poorly characterized…”
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PDTM-38. PEDIATRIC MENINGIOMAS ARE CHARACTERIZED BY DISTINCT METHYLATION PROFILES DIFFERENT FROM ADULT MENINGIOMAS
Published in Neuro-oncology (Charlottesville, Va.) (05-11-2018)“…Abstract In contrast to adulthood, meningiomas are rare among children and adolescents. However, the molecular relations between both groups have not been…”
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In comparative analysis of multi-kinase inhibitors for targeted medulloblastoma therapy pazopanib exhibits promising in vitro and in vivo efficacy
Published in Oncotarget (30-08-2014)“…Regardless of the recent advances in cytotoxic therapies, 30% of children diagnosed with medulloblastoma. succumb to the disease. Therefore, novel therapeutic…”
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5-Aminolevulinic Acid-derived Tumor Fluorescence
Published in Neurosurgery (01-03-2014)“…Abstract BACKGROUND: 5-Aminolevulinic acid is used for fluorescence-guided resections. During resection, different macroscopic fluorescence qualities…”
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Target genes of the WNT/β-catenin pathway in Wilms tumors
Published in Genes chromosomes & cancer (01-06-2006)“…The WNT/β‐catenin pathway is involved in numerous human cancers. Mutations of the CTNNB1 (β‐catenin) gene have also been detected in a subset of pediatric…”
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Temozolomide and 13-cis retinoic acid in patients with anaplastic gliomas: a prospective single-arm monocentric phase-II study (RNOP-05)
Published in Journal of neuro-oncology (01-09-2011)“…The objective of this prospective, monocentric phase-II pilot study was to evaluate toxicity and efficacy of neoadjuvant temozolomide (TMZ) and 13- cis…”
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Combined postoperative irradiation and chemotherapy for anaplastic ependymomas in childhood: results of the German prospective trials HIT 88/89 and HIT 91
Published in International journal of radiation oncology, biology, physics (15-01-2000)“…To evaluate the outcome in children with anaplastic ependymomas after surgery, irradiation, and chemotherapy; and to identify prognostic factors for survival…”
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Preradiation chemotherapy for pediatric patients with high‐grade glioma
Published in Cancer (01-01-2002)“…BACKGROUND To evaluate the feasibility and efficacy of intensive chemotherapy given prior to irradiation in pediatric patients with malignant glioma, the…”
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FIVE-AMINOLEVULlNIC ACID FOR FLUORESCENCE-GUIDED RESECTION OF RECURRENT MALIGNANT GLIOMAS: A PHASE II STUDY. Commentary
Published in Neurosurgery (2009)Get full text
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Target genes of the WNT/[beta]-catenin pathway in Wilms tumors
Published in Genes chromosomes & cancer (01-03-2006)“…The WNT/[beta]-catenin pathway is involved in numerous human cancers. Mutations of the CTNNB1 ([beta]-catenin) gene have also been detected in a subset of…”
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Oral trofosfamide and etoposide in pediatric patients with glioblastoma multiforme
Published in Cancer (15-11-2000)“…BACKGROUND Glioblastoma multiforme in childhood is rare, and the prognosis for patients with the disease is poor. The Pediatric Oncology Society of the…”
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Valproic acid as a potent substance for increasing efficacy of topoisomerase I inhibitors
Published in Turkish journal of cancer (01-07-2009)Get full text
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