Search Results - "Pietrzak, Maciej"

“Daring and Heart-Wrenching Jewish Film”— Reception of Aleksander Ford’s “Border Street” in Israel by Pietrzak, Maciej

“…The main subject of the paper is the distribution and critical reception of the film Border Street (dir. A. Ford, 1948) in Israel at the end of the 1940s…”
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Differences in Expression Level of Helios and Neuropilin-1 Do Not Distinguish Thymus-Derived from Extrathymically-Induced CD4+Foxp3+ Regulatory T Cells by Szurek, Edyta, Cebula, Anna, Wojciech, Lukasz, Pietrzak, Maciej, Rempala, Grzegorz, Kisielow, Pawel, Ignatowicz, Leszek

“…Helios transcription factor and semaphorin receptor Nrp-1 were originally described as constitutively expressed at high levels on CD4+Foxp3+ T regulatory cells…”
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BISR-RNAseq: an efficient and scalable RNAseq analysis workflow with interactive report generation by Gadepalli, Venkat Sundar, Ozer, Hatice Gulcin, Yilmaz, Ayse Selen, Pietrzak, Maciej, Webb, Amy

“…RNA sequencing has become an increasingly affordable way to profile gene expression patterns. Here we introduce a workflow implementing several open-source…”
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Altered microRNA and mRNA profiles during heart failure in the human sinoatrial node by Li, Ning, Artiga, Esthela, Kalyanasundaram, Anuradha, Hansen, Brian J., Webb, Amy, Pietrzak, Maciej, Biesiadecki, Brandon, Whitson, Bryan, Mokadam, Nahush A., Janssen, Paul M. L., Hummel, John D., Mohler, Peter J., Dobrzynski, Halina, Fedorov, Vadim V.

“…Heart failure (HF) is frequently accompanied with the sinoatrial node (SAN) dysfunction, which causes tachy-brady arrhythmias and increased mortality. MicroRNA…”
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Transcriptional profiling of human cartilage endplate cells identifies novel genes and cell clusters underlying degenerated and non-degenerated phenotypes by Kuchynsky, Kyle, Stevens, Patrick, Hite, Amy, Xie, William, Diop, Khady, Tang, Shirley, Pietrzak, Maciej, Khan, Safdar, Walter, Benjamin, Purmessur, Devina

“…Low back pain is a leading cause of disability worldwide and is frequently attributed to intervertebral disc (IVD) degeneration. Though the contributions of…”
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multi-GPA-Tree: Statistical approach for pleiotropy informed and functional annotation tree guided prioritization of GWAS results by Khatiwada, Aastha, Yilmaz, Ayse Selen, Wolf, Bethany J, Pietrzak, Maciej, Chung, Dongjun

“…Genome-wide association studies (GWAS) have successfully identified over two hundred thousand genotype-trait associations. Yet some challenges remain. First,…”
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Dormant pathogenic CD4+ T cells are prevalent in the peripheral repertoire of healthy mice by Cebula, Anna, Kuczma, Michal, Szurek, Edyta, Pietrzak, Maciej, Savage, Natasha, Elhefnawy, Wessam R., Rempala, Grzegorz, Kraj, Piotr, Ignatowicz, Leszek

“…Thymic central tolerance eliminates most immature T cells with autoreactive T cell receptors (TCR) that recognize self MHC/peptide complexes. Regardless, an…”
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Genetic analysis of a malignant meningioma and associated metastases by Huntoon, Kristin, Yilmaz, Ayse Selen, Pietrzak, Maciej, Chen, Xi, Yan, Pearlly, Toland, Amanda Ewart, Elder, J. Bradley

“…To identify genes altered in a highly aggressive metastatic meningioma primary as well as its metastases. Exome sequencing of a primary anaplastic meningioma…”
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Epigenetic silencing of nucleolar rRNA genes in Alzheimer's disease by Pietrzak, Maciej, Rempala, Grzegorz, Nelson, Peter T, Zheng, Jing-Juan, Hetman, Michal

“…Ribosomal deficits are documented in mild cognitive impairment (MCI), which often represents an early stage Alzheimer's disease (AD), as well as in advanced…”
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Self and microbiota-derived epitopes induce CD4+ T cell anergy and conversion into CD4+Foxp3+ regulatory cells by Kuczma, Michal P., Szurek, Edyta A., Cebula, Anna, Ngo, Vu L., Pietrzak, Maciej, Kraj, Piotr, Denning, Timothy L., Ignatowicz, Leszek

“…The physiological role of T cell anergy induction as a key mechanism supporting self-tolerance remains undefined, and natural antigens that induce anergy are…”
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Use of CRISPR/Cas9 with homology-directed repair to silence the human topoisomerase IIα intron-19 5' splice site: Generation of etoposide resistance in human leukemia K562 cells by Hernandez, Victor A, Carvajal-Moreno, Jessika, Wang, Xinyi, Pietrzak, Maciej, Yalowich, Jack C, Elton, Terry S

“…DNA Topoisomerase IIα (TOP2α/170) is an enzyme essential for proliferating cells. For rapidly multiplying malignancies, this has made TOP2α/170 an important…”
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Bone Morphogenic Proteins Are Immunoregulatory Cytokines Controlling FOXP3+ Treg Cells by Browning, Lauren M., Miller, Caroline, Kuczma, Michal, Pietrzak, Maciej, Jing, Yu, Rempala, Grzegorz, Muranski, Pawel, Ignatowicz, Leszek, Kraj, Piotr

“…Bone morphogenic proteins (BMPs) are members of the transforming growth factor β (TGF-β) cytokine family promoting differentiation, homeostasis, and…”
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p53-dependent repression of the human MCL-1 gene encoding an anti-apoptotic member of the BCL-2 family: the role of Sp1 and of basic transcription factor binding sites in the MCL-1 promoter by Pietrzak, Maciej, Puzianowska-Kuznicka, Monika

“…p53 regulates transcription of one anti-apoptotic and four pro-apoptotic members of the BCL-2 family, but nothing is known about the regulation of MCL-1,…”
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AmpliSeq transcriptome analysis of human alveolar and monocyte-derived macrophages over time in response to Mycobacterium tuberculosis infection by Papp, Audrey C, Azad, Abul K, Pietrzak, Maciej, Williams, Amanda, Handelman, Samuel K, Igo, Jr, Robert P, Stein, Catherine M, Hartmann, Katherine, Schlesinger, Larry S, Sadee, Wolfgang

“…Human alveolar macrophages (HAM) are primary bacterial niche and immune response cells during Mycobacterium tuberculosis (M.tb) infection, and human blood…”
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High dimensional model representation of log-likelihood ratio: binary classification with expression data by Foroughi Pour, Ali, Pietrzak, Maciej, Dalton, Lori A, Rempała, Grzegorz A

“…Binary classification rules based on a small-sample of high-dimensional data (for instance, gene expression data) are ubiquitous in modern bioinformatics…”
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Obesity-associated microbiomes instigate visceral adipose tissue inflammation by recruitment of distinct neutrophils by Shantaram, Dharti, Hoyd, Rebecca, Blaszczak, Alecia M., Antwi, Linda, Jalilvand, Anahita, Wright, Valerie P., Liu, Joey, Smith, Alan J., Bradley, David, Lafuse, William, Liu, YunZhou, Williams, Nyelia F., Snyder, Owen, Wheeler, Caroline, Needleman, Bradley, Brethauer, Stacy, Noria, Sabrena, Renton, David, Perry, Kyle A., Nagareddy, Prabha, Wozniak, Daniel, Mahajan, Sahil, Rana, Pranav S. J. B., Pietrzak, Maciej, Schlesinger, Larry S., Spakowicz, Daniel J., Hsueh, Willa A.

“…Neutrophils are increasingly implicated in chronic inflammation and metabolic disorders. Here, we show that visceral adipose tissue (VAT) from individuals with…”
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Targeting ETosis by miR-155 inhibition mitigates mixed granulocytic asthmatic lung inflammation by Kim, Ji Young, Stevens, Patrick, Karpurapu, Manjula, Lee, Hyunwook, Englert, Joshua A, Yan, Pearlly, Lee, Tae Jin, Pabla, Navjot, Pietrzak, Maciej, Park, Gye Young, Christman, John W, Chung, Sangwoon

“…Asthma is phenotypically heterogeneous with several distinctive pathological mechanistic pathways. Previous studies indicate that neutrophilic asthma has a…”
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Application of information theoretical approaches to assess diversity and similarity in single-cell transcriptomics by Seweryn, Michal T., Pietrzak, Maciej, Ma, Qin

“…Single-cell transcriptomics offers a powerful way to reveal the heterogeneity of individual cells. To date, many information theoretical approaches have been…”
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Distinctive patterns of sulfide- and butyrate-metabolizing bacteria after bariatric surgery: potential implications for colorectal cancer risk by Hussan, Hisham, Clinton, Steven K, Grainger, Elizabeth M, Webb, Maxine, Wang, Cankun, Webb, Amy, Needleman, Bradley, Noria, Sabrena, Zhu, Jiangjiang, Choueiry, Fouad, Pietrzak, Maciej, Bailey, Michael T

“…Despite improved cardiometabolic outcomes following bariatric surgery, its long-term impact on colorectal cancer (CRC) risk remains uncertain. In parallel, the…”
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graph-GPA 2.0: improving multi-disease genetic analysis with integration of functional annotation data by Deng, Qiaolan, Gupta, Arkobrato, Jeon, Hyeongseon, Nam, Jin Hyun, Yilmaz, Ayse Selen, Chang, Won, Pietrzak, Maciej, Li, Lang, Kim, Hang J, Chung, Dongjun

“…Genome-wide association studies (GWAS) have successfully identified a large number of genetic variants associated with traits and diseases. However, it still…”
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