Search Results - "Pietronigro, Enrica Caterina"
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The role of neutrophils in the dysfunction of central nervous system barriers
Published in Frontiers in aging neuroscience (11-08-2022)“…Leukocyte migration into the central nervous system (CNS) represents a central process in the development of neurological diseases with a detrimental…”
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Peli1 impairs microglial Aβ phagocytosis through promoting C/EBPβ degradation
Published in PLoS biology (01-10-2020)“…Amyloid-β (Aβ) accumulation in the brain is a hallmark of Alzheimer's disease (AD) pathology. However, the molecular mechanism controlling microglial Aβ…”
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Alpha4 beta7 integrin controls Th17 cell trafficking in the spinal cord leptomeninges during experimental autoimmune encephalomyelitis
Published in Frontiers in immunology (18-04-2023)“…Th1 and Th17 cell migration into the central nervous system (CNS) is a fundamental process in the pathogenesis of experimental autoimmune encephalomyelitis…”
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LFA-1 Controls Th1 and Th17 Motility Behavior in the Inflamed Central Nervous System
Published in Frontiers in immunology (18-10-2019)“…Leukocyte trafficking is a key event during autoimmune and inflammatory responses. The subarachnoid space (SAS) and cerebrospinal fluid are major routes for…”
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Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis
Published in Acta neuropathologica communications (03-05-2021)“…Chorea-Acanthocytosis (ChAc) is a devastating, little understood, and currently untreatable neurodegenerative disease caused by VPS13A mutations. Based on our…”
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NETosis in Alzheimer's Disease
Published in Frontiers in immunology (02-03-2017)“…Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the progressive deterioration of cognitive functions. Its neuropathological features…”
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Peli1 impairs microglial A[beta] phagocytosis through promoting C/EBP[beta] degradation
Published in PLoS biology (05-10-2020)“…Amyloid-[beta] (A[beta]) accumulation in the brain is a hallmark of Alzheimer's disease (AD) pathology. However, the molecular mechanism controlling microglial…”
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Intestinal dysbiosis promotes immune dysregulation in an animal model of Alzheimer’s disease
Published in Alzheimer's & dementia (01-12-2021)“…Background Current evidence suggests that systemic inflammation promotes Alzheimer’s Disease (AD) and recent reports demonstrated that circulating neutrophils…”
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INHIBITION OF PROTEIN ARGININE DEIMINASES IMPROVES COGNITION AND REDUCES NEUROPATHOLOGICAL CHANGES IN MOUSE MODELS OF ALZHEIMER’S DISEASE
Published in Alzheimer's & dementia (01-07-2017)Get full text
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TREATMENT WITH CALCIUM DOBESILATE REDUCES NEUROINFLAMMATION AND IMPROVES COGNITION IN A MOUSE MODEL OF ALZHEIMER’S DISEASE
Published in Alzheimer's & dementia (01-07-2017)Get full text
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LFA-1 INTEGRIN MEDIATES NEUTROPHIL TRAFFICKING IN THE BRAIN AND CONTRIBUTES TO DISEASE PATHOLOGY IN MOUSE MODELS OF ALZHEIMER’S DISEASE
Published in Alzheimer's & dementia (01-07-2016)Get full text
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O1‐11‐04: Targeting leukocyte integrins has therapeutic effect in Alzheimer's‐like disease
Published in Alzheimer's & dementia (01-07-2015)Get full text
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Targeting leukocyte integrins has therapeutic effect in Alzheimer's-like disease
Published in Alzheimer's & dementia (01-07-2015)Get full text
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