Search Results - "Pietka, Terri"

Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women by Yoshino, Mihoko, Yoshino, Jun, Kayser, Brandon D, Patti, Gary J, Franczyk, Michael P, Mills, Kathryn F, Sindelar, Miriam, Pietka, Terri, Patterson, Bruce W, Imai, Shin-Ichiro, Klein, Samuel

“…In rodents, obesity and aging impair nicotinamide adenine dinucleotide (NAD ) biosynthesis, which contributes to metabolic dysfunction. Nicotinamide…”
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Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission by Park, Hongsuk, He, Anyuan, Tan, Min, Johnson, Jordan M, Dean, John M, Pietka, Terri A, Chen, Yali, Zhang, Xiangyu, Hsu, Fong-Fu, Razani, Babak, Funai, Katsuhiko, Lodhi, Irfan J

“…Peroxisomes perform essential functions in lipid metabolism, including fatty acid oxidation and plasmalogen synthesis. Here, we describe a role for peroxisomal…”
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Endothelial cell CD36 optimizes tissue fatty acid uptake by Son, Ni-Huiping, Basu, Debapriya, Samovski, Dmitri, Pietka, Terri A, Peche, Vivek S, Willecke, Florian, Fang, Xiang, Yu, Shui-Qing, Scerbo, Diego, Chang, Hye Rim, Sun, Fei, Bagdasarov, Svetlana, Drosatos, Konstantinos, Yeh, Steve T, Mullick, Adam E, Shoghi, Kooresh I, Gumaste, Namrata, Kim, KyeongJin, Huggins, Lesley-Ann, Lhakhang, Tenzin, Abumrad, Nada A, Goldberg, Ira J

“…Movement of circulating fatty acids (FAs) to parenchymal cells requires their transfer across the endothelial cell (EC) barrier. The multiligand receptor…”
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Endothelial Cell Receptors in Tissue Lipid Uptake and Metabolism by Abumrad, Nada A., Cabodevilla, Ainara G., Samovski, Dmitri, Pietka, Terri, Basu, Debapriya, Goldberg, Ira J.

“…Lipid uptake and metabolism are central to the function of organs such as heart, skeletal muscle, and adipose tissue. Although most heart energy derives from…”
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Determination of Adipocyte Size and Number by Pietka, Terri A, Abumrad, Nada A

“…Dysfunction in adipocyte expansion during the onset of obesity is associated with metabolic abnormalities. Determination of adipocyte size and number is an…”
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Sulfo-N-succinimidyl oleate (SSO) inhibits fatty acid uptake and signaling for intracellular calcium via binding CD36 lysine 164: SSO also inhibits oxidized low density lipoprotein uptake by macrophages by Kuda, Ondrej, Pietka, Terri A, Demianova, Zuzana, Kudova, Eva, Cvacka, Josef, Kopecky, Jan, Abumrad, Nada A

“…FAT/CD36 is a multifunctional glycoprotein that facilitates long-chain fatty acid (FA) uptake by cardiomyocytes and adipocytes and uptake of oxidized low…”
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Measurement of Mitochondrial Respiration in Human and Mouse Skeletal Muscle Fibers by High-Resolution Respirometry by Pietka, Terri A, Brookheart, Rita T

“…Mitochondrial function, a cornerstone of cellular energy production, is critical for maintaining metabolic homeostasis. Its dysfunction in skeletal muscle is…”
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Role of Mineralocorticoid Receptor in Adipogenesis and Obesity in Male Mice by Ferguson, Daniel, Hutson, Irina, Tycksen, Eric, Pietka, Terri A, Bauerle, Kevin, Harris, Charles A

“…Abstract Increased visceral adiposity and hyperglycemia, 2 characteristics of metabolic syndrome, are also present in conditions of excess glucocorticoids…”
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Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity by Fabbrini, Elisa, Magkos, Faidon, Mohammed, B. Selma, Pietka, Terri, Abumrad, Nada A, Patterson, Bruce W, Okunade, Adewole, Klein, Samuel

“…Visceral adipose tissue (VAT) is an important risk factor for obesity-related metabolic disorders. Therefore, a reduction in VAT has become a key goal in…”
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Association Between Specific Adipose Tissue CD4+ T-Cell Populations and Insulin Resistance in Obese Individuals by Fabbrini, Elisa, Cella, Marina, Mccartney, Steve A, Fuchs, Anja, Abumrad, Nada A, Pietka, Terri A, Chen, Zhouji, Finck, Brian N, Han, Dong Ho, Magkos, Faidon, Conte, Caterina, Bradley, David, Fraterrigo, Gemma, Eagon, J. Christopher, Patterson, Bruce W, Colonna, Marco, Klein, Samuel

“…Background & Aims An increased number of macrophages in adipose tissue is associated with insulin resistance and metabolic dysfunction in obese people…”
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Decreased Consumption of Branched-Chain Amino Acids Improves Metabolic Health by Fontana, Luigi, Cummings, Nicole E., Arriola Apelo, Sebastian I., Neuman, Joshua C., Kasza, Ildiko, Schmidt, Brian A., Cava, Edda, Spelta, Francesco, Tosti, Valeria, Syed, Faizan A., Baar, Emma L., Veronese, Nicola, Cottrell, Sara E., Fenske, Rachel J., Bertozzi, Beatrice, Brar, Harpreet K., Pietka, Terri, Bullock, Arnold D., Figenshau, Robert S., Andriole, Gerald L., Merrins, Matthew J., Alexander, Caroline M., Kimple, Michelle E., Lamming, Dudley W.

“…Protein-restricted (PR), high-carbohydrate diets improve metabolic health in rodents, yet the precise dietary components that are responsible for these effects…”
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MANF stimulates autophagy and restores mitochondrial homeostasis to treat autosomal dominant tubulointerstitial kidney disease in mice by Kim, Yeawon, Li, Chuang, Gu, Chenjian, Fang, Yili, Tycksen, Eric, Puri, Anuradhika, Pietka, Terri A., Sivapackiam, Jothilingam, Kidd, Kendrah, Park, Sun-Ji, Johnson, Bryce G., Kmoch, Stanislav, Duffield, Jeremy S., Bleyer, Anthony J., Jackrel, Meredith E., Urano, Fumihiko, Sharma, Vijay, Lindahl, Maria, Chen, Ying Maggie

“…Misfolded protein aggregates may cause toxic proteinopathy, including autosomal dominant tubulointerstitial kidney disease due to uromodulin mutations (ADTKD-…”
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Tauroursodeoxycholic Acid May Improve Liver and Muscle but Not Adipose Tissue Insulin Sensitivity in Obese Men and Women by KARS, Marleen, LING YANG, KLEIN, Samuel, GREGOR, Margaret F, SELMA MOHAMMED, B, PIETKA, Terri A, FINCK, Brian N, PATTERSON, Bruce W, HORTON, Jay D, MITTENDORFER, Bettina, HOTAMISLIGIL, Gökhan S

“…Insulin resistance is commonly associated with obesity. Studies conducted in obese mouse models found that endoplasmic reticulum (ER) stress contributes to…”
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Subcutaneous Adipose Tissue Metabolic Function and Insulin Sensitivity in People With Obesity by Koh, Han-Chow E, van Vliet, Stephan, Pietka, Terri A, Meyer, Gretchen A, Razani, Babak, Laforest, Richard, Gropler, Robert J, Mittendorfer, Bettina

“…We used stable isotope-labeled glucose and palmitate tracer infusions, a hyperinsulinemic-euglycemic clamp, positron emission tomography of muscles and adipose…”
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Perilipin 5-Driven Lipid Droplet Accumulation in Skeletal Muscle Stimulates the Expression of Fibroblast Growth Factor 21 by Harris, Lydia-Ann L S, Skinner, James R, Shew, Trevor M, Pietka, Terri A, Abumrad, Nada A, Wolins, Nathan E

“…Perilipin 5 (PLIN5) is a lipid droplet protein and is highly expressed in oxidative tissue. Expression of the PLIN5 gene is regulated by peroxisome…”
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Microvascular insulin resistance with enhanced muscle glucose disposal in CD36 deficiency by Shibao, Cyndya A., Peche, Vivek S., Pietka, Terri A., Samovski, Dmitri, Williams, Ian M., Abumrad, Naji N., Gamazon, Eric R., Goldberg, Ira J., Wasserman, David H., Abumrad, Nada A.

“…Abstract Aims/hypothesis Microvascular dysfunction contributes to insulin resistance. CD36, a fatty acid transporter and modulator of insulin signalling, is…”
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NAD + -dependent deacetylase SIRT3 in adipocytes is dispensable for maintaining normal adipose tissue mitochondrial function and whole body metabolism by Porter, Lane C, Franczyk, Michael P, Pietka, Terri, Yamaguchi, Shintaro, Lin, Jonathan B, Sasaki, Yo, Verdin, Eric, Apte, Rajendra S, Yoshino, Jun

“…Mitochondrial dysfunction in adipose tissue is involved in the pathophysiology of obesity-induced systemic metabolic complications, such as type 2 diabetes,…”
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The Extracellular Matrix Protein MAGP1 Supports Thermogenesis and Protects Against Obesity and Diabetes Through Regulation of TGF-β by CRAFT, Clarissa S, PIETKA, Terri A, SCHAPPE, Timothy, COLEMAN, Trey, COMBS, Michelle D, KLEIN, Samuel, ABUMRAD, Nada A, MECHAM, Robert P

“…Microfibril-associated glycoprotein 1 (MAGP1) is a component of extracellular matrix microfibrils. Here we show that MAGP1 expression is significantly altered…”
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Monoacylglycerol O‐acyltransferase 1 lowers adipocyte differentiation capacity in vitro but does not affect adiposity in mice by Singer, Jason M., Shew, Trevor M., Ferguson, Daniel, Renkemeyer, M. Katie, Pietka, Terri A., Hall, Angela M., Finck, Brian N., Lutkewitte, Andrew J.

“…Objective Monoacylglycerol O‐acyltransferase 1 (Mogat1), a lipogenic enzyme that converts monoacylglycerol to diacylglycerol, is highly expressed in adipocytes…”
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Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver by Hall, Angela M., Kou, Kou, Chen, Zhouji, Pietka, Terri A., Kumar, Mrudula, Korenblat, Kevin M., Lee, Kyuha, Ahn, Kay, Fabbrini, Elisa, Klein, Samuel, Goodwin, Bryan, Finck, Brian N.

“…Intrahepatic lipid accumulation is extremely common in obese subjects and is associated with the development of insulin resistance and diabetes. Hepatic…”
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