Search Results - "Pieter S. Hiemstra"

The innate immune function of airway epithelial cells in inflammatory lung disease by Hiemstra, Pieter S, McCray, Jr, Paul B, Bals, Robert

“…The airway epithelium is now considered to be central to the orchestration of pulmonary inflammatory and immune responses, and is also key to tissue…”
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An emerging class of air pollutants: Potential effects of microplastics to respiratory human health? by Amato-Lourenço, Luís Fernando, dos Santos Galvão, Luciana, de Weger, Letty A., Hiemstra, Pieter S., Vijver, Martina G., Mauad, Thais

“…It is increasingly recognized that the ubiquity of convenient single-use plastic has resulted in a global plastic pollution challenge, with substantial…”
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Airway Epithelial Barrier Dysfunction in Chronic Obstructive Pulmonary Disease: Role of Cigarette Smoke Exposure by Aghapour, Mahyar, Raee, Pourya, Moghaddam, Seyed Javad, Hiemstra, Pieter S, Heijink, Irene H

“…The epithelial lining of the airway forms the first barrier against environmental insults, such as inhaled cigarette smoke, which is the primary risk factor…”
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Asthma-COPD overlap. Clinical relevance of genomic signatures of type 2 inflammation in chronic obstructive pulmonary disease by Christenson, Stephanie A, Steiling, Katrina, van den Berge, Maarten, Hijazi, Kahkeshan, Hiemstra, Pieter S, Postma, Dirkje S, Lenburg, Marc E, Spira, Avrum, Woodruff, Prescott G

“…Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease and likely includes a subgroup that is biologically comparable to asthma. Studying…”
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Electronic cigarettes: a task force report from the European Respiratory Society by Bals, Robert, Boyd, Jeanette, Esposito, Susanna, Foronjy, Robert, Hiemstra, Pieter S, Jiménez-Ruiz, Carlos A, Katsaounou, Paraskevi, Lindberg, Anne, Metz, Carlos, Schober, Wolfgang, Spira, Avrum, Blasi, Francesco

“…There is a marked increase in the development and use of electronic nicotine delivery systems or electronic cigarettes (ECIGs). This statement covers…”
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Human lung epithelial cell cultures for analysis of inhaled toxicants: Lessons learned and future directions by Hiemstra, Pieter S., Grootaers, Gwendolynn, van der Does, Anne M., Krul, Cyrille A.M., Kooter, Ingeborg M.

“…The epithelium that covers the conducting airways and alveoli is a primary target for inhaled toxic substances, and therefore a focus in inhalation toxicology…”
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Role of air pollutants in airway epithelial barrier dysfunction in asthma and COPD by Aghapour, Mahyar, Ubags, Niki D, Bruder, Dunja, Hiemstra, Pieter S, Sidhaye, Venkataramana, Rezaee, Fariba, Heijink, Irene H

“…Chronic exposure to environmental pollutants is a major contributor to the development and progression of obstructive airway diseases, including asthma and…”
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Mesenchymal stromal cells: a novel therapy for the treatment of chronic obstructive pulmonary disease? by Broekman, Winifred, Khedoe, Padmini P S J, Schepers, Koen, Roelofs, Helene, Stolk, Jan, Hiemstra, Pieter S

“…COPD is characterised by tissue destruction and inflammation. Given the lack of curative treatments and the progressive nature of the disease, new treatments…”
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Efficient and sensitive identification and quantification of airborne pollen using next-generation DNA sequencing by Kraaijeveld, Ken, de Weger, Letty A., Ventayol García, Marina, Buermans, Henk, Frank, Jeroen, Hiemstra, Pieter S., den Dunnen, Johan T.

“…Pollen monitoring is an important and widely used tool in allergy research and creation of awareness in pollen‐allergic patients. Current pollen monitoring…”
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Defining asthma-COPD overlap syndrome: a population-based study by Bonten, Tobias N, Kasteleyn, Marise J, de Mutsert, Renee, Hiemstra, Pieter S, Rosendaal, Frits R, Chavannes, Niels H, Slats, Annelies M, Taube, Christian

“…Asthma-chronic obstructive pulmonary disease (COPD) overlap syndrome (ACOS) seems an important clinical phenotype, but multiple definitions have been proposed…”
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Farm Dust Exposure Reduces Cytokine‐ and Rhinovirus‐Induced IL‐33 Expression in Bronchial Epithelial Cells by Schrumpf, Jasmijn A., Ninaber, Dennis K., Müller, Christoph, Rankl, Bettina, Tham, Mikaela, Mutius, Erika, Smits, Hermelijn H., Hiemstra, Pieter S.

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Brown adipose tissue takes up plasma triglycerides mostly after lipolysis by Khedoe, Padmini P.S.J., Hoeke, Geerte, Kooijman, Sander, Dijk, Wieneke, Buijs, Jeroen T., Kersten, Sander, Havekes, Louis M., Hiemstra, Pieter S., Berbée, Jimmy F.P., Boon, Mariëtte R., Rensen, Patrick C.N.

“…Brown adipose tissue (BAT) produces heat by burning TGs that are stored within intracellular lipid droplets and need to be replenished by the uptake of…”
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A novel method for expansion and differentiation of mouse tracheal epithelial cells in culture by Eenjes, Evelien, Mertens, Tinne C. J., Buscop-van Kempen, Marjon J., van Wijck, Yolanda, Taube, Christian, Rottier, Robbert J., Hiemstra, Pieter S.

“…Air-liquid interface (ALI) cultures of mouse tracheal epithelial cells (MTEC) are a well-established model to study airway epithelial cells, but current…”
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Sputum microbiota and inflammation at stable state and during exacerbations in a cohort of chronic obstructive pulmonary disease (COPD) patients by Tangedal, Solveig, Nielsen, Rune, Aanerud, Marianne, Persson, Louise J, Wiker, Harald G, Bakke, Per S, Hiemstra, Pieter S, Eagan, Tomas M

“…Exacerbations of chronic obstructive pulmonary disease (COPD) are debilitating events and spur disease progression. Infectious causes are frequent; however, it…”
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The lower airways microbiome and antimicrobial peptides in idiopathic pulmonary fibrosis differ from chronic obstructive pulmonary disease by Knudsen, Kristel S, Lehmann, Sverre, Nielsen, Rune, Tangedal, Solveig, Haaland, Ingvild, Hiemstra, Pieter S, Eagan, Tomas M

“…The lower airways microbiome and host immune response in chronic pulmonary diseases are incompletely understood. We aimed to investigate possible microbiome…”
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Innate Immunity of the Lung by Greene, Catherine M., Hiemstra, Pieter S.

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Regeneration of the lung: Lung stem cells and the development of lung mimicking devices by Schilders, Kim A A, Eenjes, Evelien, van Riet, Sander, Poot, André A, Stamatialis, Dimitrios, Truckenmüller, Roman, Hiemstra, Pieter S, Rottier, Robbert J

“…Inspired by the increasing burden of lung associated diseases in society and an growing demand to accommodate patients, great efforts by the scientific…”
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Dynamic differences in dietary polyunsaturated fatty acid metabolism in sputum of COPD patients and controls by van der Does, Anne M., Heijink, Marieke, Mayboroda, Oleg A., Persson, Louise J., Aanerud, Marianne, Bakke, Per, Eagan, Tomas M., Hiemstra, Pieter S., Giera, Martin

“…Disturbances in onset and resolution of inflammation in chronic obstructive pulmonary disease (COPD) are incompletely understood. Dietary polyunsaturated fatty…”
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The respiratory virome and exacerbations in patients with chronic obstructive pulmonary disease by van Rijn, Anneloes L, van Boheemen, Sander, Sidorov, Igor, Carbo, Ellen C, Pappas, Nikos, Mei, Hailiang, Feltkamp, Mariet, Aanerud, Marianne, Bakke, Per, Claas, Eric C J, Eagan, Tomas M, Hiemstra, Pieter S, Kroes, Aloys C M, de Vries, Jutte J C

“…Exacerbations are major contributors to morbidity and mortality in patients with chronic obstructive pulmonary disease (COPD), and respiratory bacterial and…”
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A new portable sampler to monitor pollen at street level in the environment of patients by de Weger, Letty A., Molster, Frank, de Raat, Kevin, den Haan, Jeffrey, Romein, Johan, van Leeuwen, Willem, de Groot, Hans, Mostert, Marijke, Hiemstra, Pieter S.

“…Allergic rhinitis caused by pollen exposure is one of the most common allergic diseases. Therefore monitoring pollen levels in ambient air is an important tool…”
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