Search Results - "Pierson, D.L."

Multiple latent viruses reactivate in astronauts during Space Shuttle missions by Mehta, S.K, Laudenslager, M.L, Stowe, R.P, Crucian, B.E, Sams, C.F, Pierson, D.L

“…Highlights • Latent virus reactivation increased in astronauts during Space Shuttle missions. • The molar ratio of the area under the curve (AUCg) of cortisol…”
Get full text

Reactivation of latent viruses is associated with increased plasma cytokines in astronauts by Mehta, S.K., Crucian, B.E., Stowe, R.P., Simpson, R.J., Ott, C.M., Sams, C.F., Pierson, D.L.

“…► Plasma cytokine levels in astronauts during spaceflight were measured. ► Reactivation of three latent viruses was determined by PCR in saliva. ► Cytokine…”
Get full text

Abstract # 1855 Latent virus reactivation in astronauts during international space station by Mehta, S.K, Laudenslager, M.L, Stowe, R.P, Crucian, B.E, Feiveson, A.H, Sams, C.F, Pierson, D.L

“…Latent virus reactivation and diurnal salivary cortisol and dehydroepiandrosterone (DHEA) were measured prospectively in 23 astronauts (18 male and 5 female)…”
Get full text

Latent virus reactivation: Space to earth by Mehta, S.K, Cohrs, R.J, Gilden, D.H, Tyring, S.K, Castro, V.A, Ott, C.M, Pierson, D.L

Get full text

Simulated microgravity ‘disarms’ human Natural Killer cells and suppresses cytotoxic activity against tumor target cells by Mylabathula, P.L., Bigley, A.B., Li, L., Crucian, B.E., Pierson, D.L., Mehta, S.K., Rezvani, K., Simpson, R.J.

“…Maintaining immune system integrity is of paramount importance for astronauts embarking on long-duration spaceflight missions. We have shown that Natural…”
Get full text

Relief from glucose interference in microcin B17 biosynthesis by growth in a rotating‐wall bioreactor by Fang, A, Pierson, D.L, Mishra, S.K, Demain, A.L

“…Glucose interference in production of microcin B17 by Escherichia coli ZK650 was decreased sevenfold by growth in a ground‐based rotating‐wall bioreactor…”
Get full text

Space flight alters bacterial gene expression and virulence and reveals a role for global regulator Hfq by Wilson, J.W, Ott, C.M, zu Bentrup, K. Höner, Ramamurthy, R, Quick, L, Porwollik, S, Cheng, P, McClelland, M, Tsaprailis, G, Radabaugh, T, Hunt, A, Fernandez, D, Richter, E, Shah, M, Kilcoyne, M, Joshi, L, Nelman-Gonzalez, M, Hing, S, Parra, M, Dumars, P, Norwood, K, Bober, R, Devich, J, Ruggles, A, Goulart, C, Rupert, M, Stodieck, L, Stafford, P, Catella, L, Schurr, M.J, Buchanan, K, Morici, L, McCracken, J, Allen, P, Baker-Coleman, C, Hammond, T, Vogel, J, Nelson, R, Pierson, D.L, Stefanyshyn-Piper, H.M, Nickerson, C.A

“…A comprehensive analysis of both the molecular genetic and phenotypic responses of any organism to the space flight environment has never been accomplished…”
Get full text

Latent viral reactivation is associated with changes in plasma antimicrobial protein concentrations during long-duration spaceflight by Spielmann, G., Laughlin, M.S., Kunz, H., Crucian, B.E., Quiriarte, H.D., Mehta, S.K., Pierson, D.L., Simpson, R.J.

“…Long duration spaceflights are associated with profound dysregulation of the immune system and latent viral reactivations. However, little is known on the…”
Get full text

Three-dimensional growth of extravillous cytotrophoblasts promotes differentiation and invasion by LaMarca, H.L., Ott, C.M., Höner zu Bentrup, K., LeBlanc, C.L., Pierson, D.L., Nelson, A.B., Scandurro, A.B., Whitley, G. St. J., Nickerson, C.A., Morris, C.A.

“…Human trophoblast research relies on a combination of in vitro models, including isolated primary cultures, explant cultures, and trophoblast cell lines. In…”
Get full text

Epstein–Barr virus shedding by astronauts during space flight by Pierson, D.L., Stowe, R.P., Phillips, T.M., Lugg, D.J., Mehta, S.K.

“…Patterns of Epstein–Barr virus (EBV) reactivation in 32 astronauts and 18 healthy age-matched control subjects were characterized by quantifying EBV shedding…”
Get full text

Shear stress enhances microcin B17 production in a rotating wall bioreactor, but ethanol stress does not by Gao, Q., Fang, A., Pierson, D. L., Mishra, S. K., Demain, A. L.

“…Stress, including that caused by ethanol, has been shown to induce or promote secondary metabolism in a number of microbial systems. Rotating-wall bioreactors…”
Get full text

Microbiology of the space shuttle water system by Koenig, D.W., Pierson, D.L.

“…The Space Shuttle has a once-through water system that is initially filled on the ground, partially drained before launch and then refilled with fuel-cell…”
Get full text

Relief from glucose interference in microcin B17 biosynthesis by growth in a rotating-wall bioreactor: microcin b17 biosynthesis by Fang, A., Pierson, D.L., Mishra, S.K., Demain, A.L.

Get full text

Evaluation of three portable samplers for monitoring airborne fungi by Mehta, S.K. (Government Medical College, Amritsar, India.), Mishra, S.K, Pierson, D.L

“…Airborne fungi were monitored at five sample sites with the Burkard portable, the RCS Plus, and the SAS Super 90 air samplers; the Andersen 2-stage impactor…”
Get full text

Secondary metabolism in simulated microgravity: beta-lactam production by Streptomyces clavuligerus by Fang, A., Pierson, D. L., Mishra, S. K., Koenig, D. W., Demain, A. L.

“…Rotating bioreactors designed at NASA's Johnson Space Center were used to simulate a microgravity environment in which to study secondary metabolism. The…”
Get full text

Gramicidin S production by Bacillus brevis in simulated microgravity by Fang, A., Pierson, D. L., Mishra, S. K., Koenig, D. W., Demain, A. L.

“…In a continuing study of microbial secondary metabolism in simulated microgravity, we have examined gramicidin S (GS) production by Bacillus brevis strain…”
Get full text

Evaluation of the Biolog MicroStation system for yeast identification by McGinnis, M. R., Molina, T. C., Pierson, D. L., Mishra, S. K.

“…One hundred and fifty-nine isolates representing 16 genera and 53 species of yeasts were processed with the Biolog MicroStation System for yeast…”
Get full text

Removal of Burkholderia cepacia biofilms with oxidants by Koenig, D W, Mishra, S K, Pierson, D L

“…Iodine is used to disinfect the water system aboard US space shuttles and is the anticipated biocide for the international space station. Water quality on…”
Get more information

Microbiological characterization of a regenerative life support system by Koenig, D W, Bruce, R J, Mishra, S K, Barta, D J, Pierson, D L

“…A Variable Pressure Plant Growth Chamber (VPGC), at the Johnson Space Center's (JSC) ground-based Regenerative Life Support Systems (RLSS) test bed, was used…”
Get more information

Human carbamylphosphate synthetase I. Stabilization, purification, and partial characterization of the enzyme from human liver by Pierson, D L, Brien, J M

“…Carbamylphosphate synthetase I from human liver was stabilized, purified, and partially characterized. The labile enzyme was stabilized in cell-free extracts…”
Get full text