Search Results - "Pierre FOUCHET"

EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells by Ragazzini, Roberta, Pérez-Palacios, Raquel, Baymaz, Irem H., Diop, Seynabou, Ancelin, Katia, Zielinski, Dina, Michaud, Audrey, Givelet, Maëlle, Borsos, Mate, Aflaki, Setareh, Legoix, Patricia, Jansen, Pascal W. T. C., Servant, Nicolas, Torres-Padilla, Maria-Elena, Bourc’his, Deborah, Fouchet, Pierre, Vermeulen, Michiel, Margueron, Raphaël

“…The Polycomb group of proteins is required for the proper orchestration of gene expression due to its role in maintaining transcriptional silencing. It is…”
Get full text

Competition for Food Drives Stem Cell Fate in Facultative Niches by Givelet, Maëlle, Lapoujade, Clémentine, Fouchet, Pierre

“…Mechanisms regulating maintenance of the stem cell pool in facultative niches of the mammalian testis are poorly understood. In this issue of Cell Stem Cell,…”
Get full text

Revealing cellular and molecular transitions in neonatal germ cell differentiation using single cell RNA sequencing by Liao, Jinyue, Ng, Shuk Han, Luk, Alfred Chun, Suen, Hoi Ching, Qian, Yan, Lee, Annie Wing Tung, Tu, Jiajie, Fung, Jacqueline Chak Lam, Tang, Nelson Leung Sang, Feng, Bo, Chan, Wai Yee, Fouchet, Pierre, Hobbs, Robin M, Lee, Tin Lap

“…Neonatal germ cell development provides the foundation of spermatogenesis. However, a systematic understanding of this process is still limited. To resolve…”
Get full text

Mouse differentiating spermatogonia can generate germinal stem cells in vivo by Coureuil, Mathieu, Barroca, Vilma, Lassalle, Bruno, Fouchet, Pierre, Testart, Jacques, Louis, Jean Paul, Le Page, Florence, Riou, Lydia, Allemand, Isabelle

“…In adults, stem cells are responsible for the maintenance of many actively renewing tissues, such as haematopoietic, skin, gut and germinal tissues. These stem…”
Get full text

The netrin-1 receptor UNC5C contributes to the homeostasis of undifferentiated spermatogonia in adult mice by Barroca, Vilma, Racine, Chrystele, Pays, Laurent, Fouchet, Pierre, Coureuil, Mathieu, Allemand, Isabelle

“…•The Netrin-1 receptor UNC5c is expressed in undifferentiated spermatogonia.•Loss of Unc5c impairs the differentiation of spermatogonia.•Phenotype worsens with…”
Get full text

Contribution of Single-Cell Transcriptomics to the Characterization of Human Spermatogonial Stem Cells: Toward an Application in Male Fertility Regenerative Medicine? by Gille, Anne-Sophie, Lapoujade, Clémentine, Wolf, Jean-Philippe, Fouchet, Pierre, Barraud-Lange, Virginie

“…Ongoing progress in genomic technologies offers exciting tools that can help to resolve transcriptome and genome-wide DNA modifications at single-cell…”
Get full text

In vivo cellular imaging pinpoints the role of reactive oxygen species in the early steps of adult hematopoietic reconstitution by Lewandowski, Daniel, Barroca, Vilma, Ducongé, Frédéric, Bayer, Jan, Van Nhieu, Jeanne Tran, Pestourie, Carine, Fouchet, Pierre, Tavitian, Bertrand, Roméo, Paul-Henri

“…Few techniques are available to characterize in vivo the early cellular dynamics of long-term reconstitution of hematopoiesis after transplantation of…”
Get full text

Flow cytometric characterization of viable meiotic and postmeiotic cells by Hoechst 33342 in mouse spermatogenesis by Bastos, Henri, Lassalle, Bruno, Chicheportiche, Alexandra, Riou, Lydia, Testart, Jacques, Allemand, Isabelle, Fouchet, Pierre

“…Background Spermatogenesis in adult is a complex stepwise process leading to terminally differentiated spermatozoa. The cellular heterogeneity of testis…”
Get full text

Side Population' cells in adult mouse testis express Bcrp1 gene and are enriched in spermatogonia and germinal stem cells by Lassalle, Bruno, Bastos, Henri, Louis, Jean Paul, Riou, Lydia, Testart, Jacques, Dutrillaux, Bernard, Fouchet, Pierre, Allemand, Isabelle

“…Stem cells in various somatic tissues (bone marrow, skeletal muscle) can be identified by the `Side Population' marker based on Hoechst 33342 efflux. We show…”
Get full text

Puma and Trail/Dr5 pathways control radiation-induced apoptosis in distinct populations of testicular progenitors by Coureuil, Mathieu, Ugolin, Nicolas, Tavernier, Marie, Chevillard, Sylvie, Barroca, Vilma, Fouchet, Pierre, Allemand, Isabelle

“…Spermatogonia- stem cells and progenitors of adult spermatogenesis- are killed through a p53-regulated apoptotic process after gamma-irradiation but the death…”
Get full text

Fanconi DNA repair pathway is required for survival and long-term maintenance of neural progenitors by Sii-Felice, Karine, Etienne, Olivier, Hoffschir, Françoise, Mathieu, Céline, Riou, Lydia, Barroca, Vilma, Haton, Céline, Arwert, Fré, Fouchet, Pierre, Boussin, François D, Mouthon, Marc-André

“…Although brain development abnormalities and brain cancer predisposition have been reported in some Fanconi patients, the possible role of Fanconi DNA repair…”
Get full text

Impaired functionality and homing of Fancg-deficient hematopoietic stem cells by Barroca, Vilma, Mouthon, Marc André, Lewandowski, Daniel, Brunet de la Grange, Philippe, Gauthier, Laurent Robert, Pflumio, Françoise, Boussin, François Dominique, Arwert, Fre, Riou, Lydia, Allemand, Isabelle, Romeo, Paul Henri, Fouchet, Pierre

“…Fanconi anemia (FA) is a human rare genetic disorder characterized by congenital defects, bone marrow (BM) failure and predisposition to leukemia. The…”
Get full text

Similarities and Differences in the In Vivo Response of Mouse Neonatal Gonocytes and Spermatogonia to Genotoxic Stress by Forand, Anne, Fouchet, Pierre, Lahaye, Jean-Baptiste, Chicheportiche, Alexandra, Habert, René, Bernardino-Sgherri, Jacqueline

“…Neonatal gonocytes are the precursors of both spermatogonial stem cells and spermatogonia; thus, any persistant DNA damage in these cells may lead to heritable…”
Get full text

Neural stem cells from mouse forebrain are contained in a population distinct from the ‘side population’ by Mouthon, Marc‐André, Fouchet, Pierre, Mathieu, Céline, Sii‐Felice, Karine, Etienne, Olivier, Lages, Céline Silva, Boussin, François D.

“…Developing and adult forebrains contain neural stem cells (NSCs) but no marker is available to highly purify them. When analysed by flow cytometry, stem cells…”
Get full text

Role of Fanconi DNA repair pathway in neural stem cell homeostasis by Sii-Felice, Karine, Barroca, Vilma, Etienne, Olivier, Riou, Lydia, Hoffschir, Françoise, Fouchet, Pierre, Boussin, François D., Mouthon, Marc-André

“…Defects in DNA repair pathways have been involved in collapse of early neurogenesis leading to brain development abnormalities and embryonic lethality…”
Get full text

Similarities and Differences in the In Vivo Response of Mouse Neonatal Gonocytes and Spermatogonia to Genotoxic Stress1 by Forand, Anne, Fouchet, Pierre, Lahaye, Jean-Baptiste, Chicheportiche, Alexandra, Habert, René, Bernardino-Sgherri, Jacqueline

“…Neonatal gonocytes are the precursors of both spermatogonial stem cells and spermatogonia; thus, any persistant DNA damage in these cells may lead to heritable…”
Get full text

The Telomerase Activity of Adult Mouse Testis Resides in the Spermatogonial α6-Integrin-Positive Side Population Enriched in Germinal Stem Cells by Riou, Lydia, Bastos, Henri, Lassalle, Bruno, Coureuil, Mathieu, Testart, Jacques, Boussin, François D, Allemand, Isabelle, Fouchet, Pierre

“…Testis is one of the organs with the most telomerase activity in the adult. This activity protects chromosomes from telomere attrition and ensures the…”
Get full text

Origin of the complex karyotype of the polyploid parthenogenetic grasshopper Saga pedo (Orthoptera: Tettigoniidae) by Anne Marie DUTRILLAUX, Michèle LEMONNIER-DARCEMONT, Christian DARCEMONT, Vladimir KRPAČ, Pierre FOUCHET, Bernard DUTRILLAUX

“…Karyotypes of the polyploid parthenogenetic species Saga pedo from four localities in France and the Republic of Macedonia were constructed and compared. All…”
Get full text

DNMT3A-dependent DNA methylation is required for spermatogonial stem cells to commit to spermatogenesis by Dura, Mathilde, Teissandier, Aurélie, Armand, Mélanie, Barau, Joan, Lapoujade, Clémentine, Fouchet, Pierre, Bonneville, Lorraine, Schulz, Mathieu, Weber, Michael, Baudrin, Laura G., Lameiras, Sonia, Bourc’his, Deborah

“…DNA methylation plays a critical role in spermatogenesis, as evidenced by the male sterility of DNA methyltransferase (DNMT) mutant mice. Here, we report a…”
Get full text

Fine deletion mapping of chromosome 8p in non‐small‐cell lung carcinoma by Lerebours, Florence, Olschwang, Sylviane, Thuille, Bénédicte, Schmitz, Annette, Fouchet, Pierre, Buecher, Bruno, Martinet, Nadine, Galateau, Françoise, Thomas, Gilles

“…Several somatic genetic alterations have been described in non‐small‐cell lung carcinomas (NSCLC). Recurrent chromosomal deletions have suggested the presence…”
Get full text