Search Results - "Pierre, Fabrice H."
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Food-grade TiO2 impairs intestinal and systemic immune homeostasis, initiates preneoplastic lesions and promotes aberrant crypt development in the rat colon
Published in Scientific reports (20-01-2017)“…Food-grade titanium dioxide (TiO 2 ) containing a nanoscale particle fraction (TiO 2 -NPs) is approved as a white pigment (E171 in Europe) in common…”
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Calcium and α-tocopherol suppress cured-meat promotion of chemically induced colon carcinogenesis in rats and reduce associated biomarkers in human volunteers
Published in The American journal of clinical nutrition (01-11-2013)“…Background: Processed meat intake has been associated with increased colorectal cancer risk. We have shown that cured meat promotes carcinogen-induced…”
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Red Wine and Pomegranate Extracts Suppress Cured Meat Promotion of Colonic Mucin-Depleted Foci in Carcinogen-Induced Rats
Published in Nutrition and cancer (17-02-2017)“…Processed meat intake is carcinogenic to humans. We have shown that intake of a workshop-made cured meat with erythorbate promotes colon carcinogenesis in…”
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Calcium inhibits promotion by hot dog of 1,2‐dimethylhydrazine‐induced mucin‐depleted foci in rat colon
Published in International journal of cancer (01-12-2013)“…Epidemiology suggests that processed meat is associated with colorectal cancer risk, but few experimental studies support this association. We have shown that…”
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Dietary iron intake and breast cancer risk: modulation by an antioxidant supplementation
Published in Oncotarget (29-11-2016)“…Experimental results suggested that iron-induced lipid peroxidation may explain the direct associations observed between red/processed meat intakes and…”
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Freeze-Dried Ham Promotes Azoxymethane-Induced Mucin-Depleted Foci and Aberrant Crypt Foci in Rat Colon
Published in Nutrition and cancer (01-07-2010)“…Processed and red meat consumption is associated with the risk of colorectal cancer. Meta-analyses have suggested that the risk associated with processed meat…”
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Calcium carbonate suppresses haem toxicity markers without calcium phosphate side effects on colon carcinogenesis
Published in British journal of nutrition (14-02-2011)“…Red meat intake is associated with an increased risk of colorectal cancer. We have previously shown that haemin, Hb and red meat promote carcinogen-induced…”
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Red and processed meat intake and cancer risk: Results from the prospective NutriNet‐Santé cohort study
Published in International journal of cancer (15-01-2018)“…The International Agency for Research on Cancer (WHO‐IARC) classified red meat and processed meat as probably carcinogenic and carcinogenic for humans,…”
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A central role for heme iron in colon carcinogenesis associated with red meat intake
Published in Cancer research (Chicago, Ill.) (01-03-2015)“…Epidemiology shows that red and processed meat intake is associated with an increased risk of colorectal cancer. Heme iron, heterocyclic amines, and endogenous…”
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Heme iron from meat and risk of colorectal cancer: a meta-analysis and a review of the mechanisms involved
Published in Cancer prevention research (Philadelphia, Pa.) (01-02-2011)“…Red meat and processed meat intake is associated with a risk of colorectal cancer, a major cause of death in affluent countries. Epidemiological and…”
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Association between a pro plant‐based dietary score and cancer risk in the prospective NutriNet‐santé cohort
Published in International journal of cancer (01-11-2018)“…Diverse plant products (e.g. fruits, vegetables, legumes) are associated with decreased cancer risk at several locations while red and processed meat were…”
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Alcoholic beverages, obesity, physical activity and other nutritional factors, and cancer risk: A review of the evidence
Published in Critical reviews in oncology/hematology (01-03-2016)“…Abstract Purpose Prevention is a priority in the fight against cancers, especially nutritional prevention. To update the levels of evidence of relationships…”
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Heme Iron Intake, Dietary Antioxidant Capacity, and Risk of Colorectal Adenomas in a Large Cohort Study of French Women
Published in Cancer epidemiology, biomarkers & prevention (01-04-2016)“…Nitrosylated and non-nitrosylated heme iron from red processed and nonprocessed meat have been associated with increased colorectal carcinogenesis. Mechanisms…”
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Food-grade titanium dioxide translocates across the buccal mucosa in pigs and induces genotoxicity in an in vitro model of human oral epithelium
Published in Nanotoxicology (01-06-2023)“…The whitening and opacifying agent titanium dioxide (TiO 2 ) is used worldwide in various foodstuffs, toothpastes and pharmaceutical tablets. Its use as a food…”
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Red meat and colorectal cancer: Nrf2-dependent antioxidant response contributes to the resistance of preneoplastic colon cells to fecal water of hemoglobin- and beef-fed rats
Published in Carcinogenesis (New York) (01-06-2016)“…Epidemiological studies have associated red meat intake with risk of colorectal cancer. Experimental studies explain this positive association by the oxidative…”
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Short-Term and Long-Term Carcinogenic Effects of Food Contaminants (4-Hydroxynonenal and Pesticides) on Colorectal Human Cells: Involvement of Genotoxic and Non-Genomic Mechanisms
Published in Cancers (27-08-2021)“…To investigate environmental impacts upon colorectal carcinogenesis (CRC) by diet, we assessed two western diet food contaminants: 4-hydroxynonenal (HNE), a…”
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Targeting Colon Luminal Lipid Peroxidation Limits Colon Carcinogenesis Associated with Red Meat Consumption
Published in Cancer prevention research (Philadelphia, Pa.) (01-09-2018)“…Red meat is probably carcinogenic to humans (WHO/IARC class 2A), in part through heme iron-induced lipoperoxidation. Here, we investigated whether red meat…”
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Food-Grade TIO2 Pigment Initiates Preneoplastic Lesions and Promotes Aberrant Crypt Development in the Rat Colon
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2017)Get full text
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Maternal heme-enriched diet promotes a gut pro-oxidative status associated with microbiota alteration, gut leakiness and glucose intolerance in mice offspring
Published in Redox biology (01-07-2022)“…Maternal environment, including nutrition and microbiota, plays a critical role in determining offspring's risk of chronic diseases such as diabetes later in…”
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