Search Results - "Pierrat, Frank A"

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    (.+-.)-9-Amino-1,2,3,4-tetrahydroacridin-1-ol. A potential Alzheimer's disease therapeutic of low toxicity by Shutske, Gregory M, Pierrat, Frank A, Cornfeldt, Michael L, Szewczak, Mark R, Huger, Francis P, Bores, Gina M, Haroutunian, Vahram, Davis, Kenneth L

    Published in Journal of medicinal chemistry (01-07-1988)
    “…A recent clinical report on the efficacy of the cholinesterase inhibitor 1,2,3,4-tetrahydro-9-acridinamine (THA, tacrine) created hope that at least a "first…”
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    Journal Article
  2. 2

    9-Amino-1,2,3,4-tetrahydroacridin-1-ols. Synthesis and evaluation as potential Alzheimer's disease therapeutics by Shutske, Gregory M, Pierrat, Frank A, Kapples, Kevin J, Cornfeldt, Michael L, Szewczak, Mark R, Huger, Francis P, Bores, Gina M, Haroutunian, Vahram, Davis, Kenneth L

    Published in Journal of medicinal chemistry (01-08-1989)
    “…The synthesis of a series of 9-amino-1,2,3,4-tetrahydroacridin-1-ols is reported. These compounds are related to 1,2,3,4-tetrahydro-9-acridinamine (THA,…”
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    Journal Article