Search Results - "Pierpont, Timothy M."

Past, Present, and Future of Rituximab-The World's First Oncology Monoclonal Antibody Therapy by Pierpont, Timothy M, Limper, Candice B, Richards, Kristy L

“…Rituximab is a chimeric mouse/human monoclonal antibody (mAb) therapy with binding specificity to CD20. It was the first therapeutic antibody approved for…”
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Chemotherapy-Induced Depletion of OCT4-Positive Cancer Stem Cells in a Mouse Model of Malignant Testicular Cancer by Pierpont, Timothy M., Lyndaker, Amy M., Anderson, Claire M., Jin, Qiming, Moore, Elizabeth S., Roden, Jamie L., Braxton, Alicia, Bagepalli, Lina, Kataria, Nandita, Hu, Hilary Zhaoxu, Garness, Jason, Cook, Matthew S., Capel, Blanche, Schlafer, Donald H., Southard, Teresa, Weiss, Robert S.

“…Testicular germ cell tumors (TGCTs) are among the most responsive solid cancers to conventional chemotherapy. To elucidate the underlying mechanisms, we…”
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Award Winner in the Young Investigator Category, 2017 Society for Biomaterials Annual Meeting and Exposition, Minneapolis, MN, April 05—08, 2017: Lymph node stiffness‐mimicking hydrogels regulate human B‐cell lymphoma growth and cell surface receptor expression in a molecular subtype‐specific manner by Apoorva, F.N.U., Tian, Ye F., Pierpont, Timothy M., Bassen, David M., Cerchietti, Leandro, Butcher, Jonathan T., Weiss, Robert S., Singh, Ankur

“…Diffuse large B‐cell lymphoma (DLBCL) is the most common type of non‐Hodgkin's lymphoma, with multiple molecular subtypes. The activated B‐cell‐like DLBCL…”
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Effects of PFOS and cyclophosphamide exposure on immune homeostasis in mice by Pierpont, Timothy M., Limper, Candice, Elmore, Jessica, Redko, Amie, Anannya, Orchi, Imbiakha, Brian, Villanueva, Alanis, Anronikov, Sasha, Bondah, Narda, Chang, Sue, Sahler, Julie, August, Avery

“…Perfluorooctane sulfonic acid (PFOS) is member of a class of molecules with fluorinated carbon chains known as polyfluoroalkyls. PFOS have been used to produce…”
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A Genetically Engineered Mouse Model of Malignant Testicular Germ Cell Tumors by Lyndaker, Amy M, Pierpont, Timothy M, Loehr, Amanda R, Weiss, Robert S

“…Testicular germ cell tumors (TGCTs) are among the most curable solid cancers and are typically highly responsive to conventional DNA-damaging chemotherapies,…”
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Nuclear RNR-α antagonizes cell proliferation by directly inhibiting ZRANB3 by Fu, Yuan, Long, Marcus J. C., Wisitpitthaya, Somsinee, Inayat, Huma, Pierpont, Timothy M., Elsaid, Islam M., Bloom, Jordana C., Ortega, Joaquin, Weiss, Robert S., Aye, Yimon

“…Since the origins of DNA-based life, the enzyme ribonucleotide reductase (RNR) has spurred proliferation because of its rate-limiting role in de novo…”
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Effects of Perfluorohexane Sulfonate Exposure on Immune Cell Populations in Naive Mice by Pierpont, Timothy M, Elmore, Jessica, Redko, Amie, Anannya, Orchi, Imbiakha, Brian, O'Hare, Katelyn, Villanueva, Alanis, Anronikov, Sasha, Bondah, Narda, Chang, Sue, Sahler, Julie, August, Avery

“…Perfluorohexane sulfonate (PFHxS) is a member of the per- and polyfluoroalkyls (PFAS) superfamily of molecules, characterized by their fluorinated carbon…”
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Targeting Cancer Stem Cells with Differentiation Agents as an Alternative to Genotoxic Chemotherapy for the Treatment of Malignant Testicular Germ Cell Tumors by Loehr, Amanda R, Pierpont, Timothy M, Gelsleichter, Eric, Galang, Anabella Maria D, Fernandez, Irma R, Moore, Elizabeth S, Guo, Matthew Z, Miller, Andrew D, Weiss, Robert S

“…Testicular germ cell tumors (TGCTs) are exceptionally sensitive to genotoxic chemotherapy, resulting in a high cure rate for the young men presenting with…”
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A novel mouse model to elucidate the origins and therapeutic sensitivity of testicular germ cell tumors by Pierpont, Timothy M

“…Testicular germ cell tumors (TGCTs) are the most common malignancy among young men. These cancers are exquisitely sensitive to genotoxic chemotherapies, even…”
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