Search Results - "Pierotti, Catia L."

The Lck inhibitor, AMG-47a, blocks necroptosis and implicates RIPK1 in signalling downstream of MLKL by Jacobsen, Annette V., Pierotti, Catia L., Lowes, Kym N., Au, Amanda E., Zhang, Ying, Etemadi, Nima, Fitzgibbon, Cheree, Kersten, Wilhelmus J. A., Samson, André L., van Delft, Mark F., Huang, David C. S., Sabroux, Hélène Jousset, Lessene, Guillaume, Silke, John, Murphy, James M.

“…Necroptosis is a form of caspase-independent programmed cell death that arises from disruption of cell membranes by the mixed lineage kinase domain-like (MLKL)…”
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Necroptosis in chronic obstructive pulmonary disease, a smoking gun? by Pierotti, Catia L, Silke, John

“…Recent studies, reviewed here, using a cigarette smoke exposure model for chronic obstructive pulmonary disease (COPD) in Ripk3 and Mlkl knock‐out mice, and…”
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The VEGFR/PDGFR tyrosine kinase inhibitor, ABT-869, blocks necroptosis by targeting RIPK1 kinase by Pierotti, Catia L, Jacobsen, Annette V, Grohmann, Christoph, Dempsey, Ruby K, Etemadi, Nima, Hildebrand, Joanne M, Fitzgibbon, Cheree, Young, Samuel N, Davies, Katherine A, Kersten, Wilhelmus J A, Silke, John, Lowes, Kym N, Jousset Sabroux, Hélène, Huang, David C S, van Delft, Mark F, Murphy, James M, Lessene, Guillaume

“…Necroptosis is a mode of programmed, lytic cell death that is executed by the mixed lineage kinase domain-like (MLKL) pseudokinase following activation by the…”
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Potent Inhibition of Necroptosis by Simultaneously Targeting Multiple Effectors of the Pathway by Pierotti, Catia L., Tanzer, Maria C., Jacobsen, Annette V., Hildebrand, Joanne M., Garnier, Jean-Marc, Sharma, Pooja, Lucet, Isabelle S., Cowan, Angus D., Kersten, Wilhelmus J. A., Luo, Meng-Xiao, Liang, Lung-Yu, Fitzgibbon, Cheree, Garnish, Sarah E., Hempel, Anne, Nachbur, Ueli, Huang, David C. S., Czabotar, Peter E., Silke, John, van Delft, Mark F., Murphy, James M., Lessene, Guillaume

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