Search Results - "Piergies, A. A."

Pharmacokinetics of tacrolimus in liver transplant patients by Jusko, W J, Piekoszewski, W, Klintmalm, G B, Shaefer, M S, Hebert, M F, Piergies, A A, Lee, C C, Schechter, P, Mekki, Q A

“…To characterize the pharmacokinetics of the immunosuppressive agent tacrolimus (FK 506) in liver transplant patients. Patients (n = 16) were assessed during…”
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Comparative efficacy of new investigational agents against Helicobacter pylori by Osato, M. S., Reddy, S. G., Piergies, A. A., Bochenek, W. J., Testa, R. T., Graham, D. Y.

“…Background: Emergence of antibiotic resistant Helicobacter pylori has necessitated the identification of alternate therapies for the treatment of this…”
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A concurrent audit of high digoxin plasma levels by Piergies, A A, Worwag, E M, Atkinson, Jr, A J

“…A concurrent audit was made of 92 patients with plasma or serum digoxin levels of 3.0 ng/ml or more. Evidence of digoxin toxicity was present in 44 of these…”
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Pharmacokinetic study of the interaction between rifabutin and delavirdine mesylate in HIV-1 infected patients by Borin, Marie T, Chambers, James H, Carel, Barbara J, Freimuth, William W, Aksentijevich, Sophia, Piergies, Antoni A

“…The oxidative metabolism of delavirdine, a non-nucleoside inhibitor of HIV-1 reverse transcriptase, is mediated in part by cytochrome P450 3A. The influence of…”
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The effect of co-administration of zolpidem with fluoxetine: pharmacokinetics and pharmacodynamics by Piergies, A A, Sweet, J, Johnson, M, Roth-Schechter, B F, Allard, S

“…Since early treatment of depression with Selective Serotonin Reuptake Inhibitor (SSRI) can be associated with insomnia, daytime antidepressive therapy with…”
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Multiple Dose Pharmacokinetics of Paroxetine in Children and Adolescents with Major Depressive Disorder or Obsessive-Compulsive Disorder by FINDLING, Robert L, NUCCI, Gianluca, PIERGIES, Antoni A, GOMENI, Roberto, BARTOLIC, Edward I, FONG, Regan, CARPENTER, David J, LEEDER, J. Steven, GAEDIGK, Andrea, DANOFF, Theodore M

“…The current study examined the pharmacokinetics (PK), safety, and tolerability of paroxetine after repeated multiple oral dosing in children and adolescents…”
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Assessment of coagulation system activation using spot urine measurements by Lind, S E, Goldshteyn, S, Barry, C P, Lindquist, J R, Piergies, A A, Rosen, T, Schneider, J R, Shevrin, D H, Caprini, J A

“…Coagulation system activation is most commonly assessed by measuring levels of one or more proteins in peripheral blood. Because faulty blood-drawing can cause…”
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Lack of cross-reactivity of Ambien (zolpidem) with drugs in standard urine drug screens by Piergies, A A, Sainati, S, Roth-Schechter, B

“…To determine in healthy volunteers (men and women; 18 to 40 years old) the potential cross-reactivity of Ambien (zolpidem) and/or its metabolites with drugs…”
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Clinical pharmacology and first-time-in-man studies: the FDA levels the playing field by Luderer, J, Piergies, A A, Jorkasky, D, Sedman, A, Reele, S, Froehlich, J, Cavanaugh, J, Steinman, G L

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Pharmacokinetics and acute cardiovascular effects of menogaril in patients with metastatic tumors by Piergies, A A, Benson, 3rd, A B

“…The new anthracyclin, menogaril [7-(R)-0-methylnogarol], is reported to produce less cardiotoxicity than doxorubicin after multiple doses. This study was…”
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Pharmacokinetics of N-acetylprocainamide in patients profiled with a stable isotope method by Atkinson, Jr, A J, Ruo, T I, Piergies, A A, Breiter, H C, Connelly, T J, Sedek, G S, Juan, D, Hubler, G L, Hsieh, A M

“…N-Acetylprocainamide (NAPA) absorption and disposition were profiled in five patients with ventricular arrhythmias by the simultaneous intravenous…”
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Effect kinetics of N-acetylprocainamide-induced QT interval prolongation by Piergies, A A, Ruo, T I, Jansyn, E M, Belknap, S M, Atkinson, Jr, A J

“…We attempted to correlate clinical response with the effects of N-acetylprocainamide (NAPA) on the QT interval in five patients with stable chronic ventricular…”
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Activation of renin-angiotensin system does not cause skeletal muscle cramps during hemodialysis by Piergies, A A, Atkinson, Jr, A J, Hubler, G L, del Greco, F

“…Activation of the renin-angiotensin system usually occurs during hemodialysis and in hemodialyzed normal dogs parallels reductions in blood flow to a tissue…”
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Torsade de pointes induced by N-Acetylprocainamide by Chow, May J., Piergies, Antoni A., Bowsher, Dennis J., Murphy, John J., Kushner, William, Ruo, Tsuen Ih, Asada, Akira, Talano, James V., Atkinson, Arthur J.

“…N-Acetylprocainamide (NAPA), a class III antiarrhythmic drug, caused torsade de pointes in a 72 year old woman who had this arrhythmia on two previous…”
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Comparison of the pharmacokinetic and pharmacodynamic properties of procainamide and N-acetylprocainamide by Atkinson, Jr, A J, Ruo, T I, Piergies, A A

“…Although procainamide (PA) has been widely used to treat patients with both ventricular and supraventricular arrhythmias since 1951, more than twenty years…”
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Metabolism and Excretion of [14C]Celecoxib in Healthy Male Volunteers by PAULSON, S. K, HRIBAR, J. D, LIU, N. W. K, HAJDU, E, BIBLE, R. H, PIERGIES, A, KARIM, A

“…We determined the disposition of a single 300-mg dose of [ 14 C]celecoxib in eight healthy male subjects. The [ 14 C]celecoxib was administered as a fine…”
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Pharmacokinetic interaction between ritonavir and didanosine when administered concurrently to HIV-infected patients by CATO, A. III, JIANG QIAN, HSU, A, VOMVOURAS, S, PIERGIES, A. A, LEONARD, J, GRANNEMAN, R

“…The effect of coadministration of ritonavir and didanosine (ddI) on the pharmacokinetics of these drugs was investigated in a single-center, three-period,…”
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Radioimmunodetection and radioimmunotherapy of cutaneous T cell lymphomas using an 131I-labeled monoclonal antibody: an Illinois Cancer Council Study by Rosen, S T, Zimmer, A M, Goldman-Leikin, R, Gordon, L I, Kazikiewicz, J M, Kaplan, E H, Variakojis, D, Marder, R J, Dykewicz, M S, Piergies, A

“…A radiolabeled murine monoclonal antibody (T101) was used for imaging and therapy of six patients with cutaneous T cell lymphoma (CTCL). Radioimmunodetection…”
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Celecoxib Does Not Significantly Alter the Pharmacokinetics or Hypoprothrombinemic Effect of Warfarin in Healthy Subjects by Karim, Aziz, Tolbert, Dwain, Piergies, Antoni, Hubbard, Richard C., Harper, Kathleen, Wallemark, Carl-Bertil, Slater, Margaret, Geis, G. Steven

“…The objective of this study was to determine the effects of celecoxib, an anti‐inflammatory/analgesic agent that primarily inhibits COX‐2 and not COX‐1 at…”
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An Open, Comparative Study of Sulbactam plus Ampicillin vs. Cefotaxime as Initial Therapy for Serious Soft Tissue and Bone and Joint Infections by L. Löffler, A. Bauernfeind, W. Keyl, B. Hoffstedt, A. Piergies, Lenz, W.

“…In an open, randomized, comparative study, patients with bone, joint, or soft-tissue infections were treated with sulbactam sodium plus ampicillin…”
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