Search Results - "Pierens, Gregory"

1H and 13C NMR scaling factors for the calculation of chemical shifts in commonly used solvents using density functional theory by Pierens, Gregory K.

“…Calculation of NMR chemical shifts and coupling constants using quantum mechanical calculations [density functional theory (DFT)], has become a very popular…”
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A New Metric for Evaluating DFT Calculated Proton and Carbon Chemical Shifts of Natural Products and Organic Compounds by Pierens, Gregory K.

“…The calculation of DFT (density functional theory) chemical shifts have become an important technique for the verification of a proposed structure. An easily…”
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Revision of the Structure of Acremine P from a Marine-Derived Strain of Acremonium persicinum by Garson, Mary J, Hehre, Warren, Pierens, Gregory K, Suciati

“…The previously published structure of the fungal metabolite acremine P is revised by re-evaluation of chemical shift values and NOESY data, and by DFT…”
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NMR and DFT investigations of structure of colchicine in various solvents including density functional theory calculations by Pierens, Gregory K., Venkatachalam, T. K., Reutens, David C.

“…A detailed NMR investigation of the chemical shifts of hydrogen and carbon atoms associated with the structure of the naturally occurring alkaloid colchicine…”
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seco-1-Azacubane-2-carboxylic acid–Amide Bond Comparison to Proline by Fahrenhorst-Jones, Tyler, Kong, Dehui, Burns, Jed M., Pierens, Gregory K., Bernhardt, Paul V., Savage, G. Paul, Williams, Craig M.

“…seco-1-Azacubane-2-carboxylic acid, an unusual and sterically constrained amino acid, was found to undergo amide bond formation at both the N- and C-termini…”
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Structural diversity in nudibranch chemistry: elucidation of norditerpenes with a dendrillane scaffold from the Australian nudibranch Goniobranchus coi by ster, Louise C, Pierens, Gregory K, De Voss, James J, Garson, Mary J

“…In addition to three known compounds (1–3), two new rearranged spongian diterpenes (4 and 5) with perhydroazulene and dioxabicyclooctane ring systems were…”
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The (±)-5-Aza[1.0]triblattane Skeleton via Azetine Cycloaddition by Su, Chuyi, Dallaston, Madeleine A., Watson, Renée D., Fahrenhorst-Jones, Tyler, Cameron, Jacob P., Pierens, Gregory K., Bernhardt, Paul V., Savage, G. Paul, Williams, Craig M.

“…The first synthesis of the 5-aza[1.0]­triblattane skeleton was achieved through a [4 + 2] cycloaddition approach using a suitably protected azetine and…”
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9‐Azahomocubane by Fahrenhorst‐Jones, Tyler, Marshall, David L., Burns, Jed M., Pierens, Gregory K., Van Meurs, Derek P., Kong, Dehui, Bernhardt, Paul V., Blanksby, Stephen J., Savage, G. Paul, Eaton, Philip E., Williams, Craig M.

“…Homocubane, a highly strained cage hydrocarbon, contains two very different positions for the introduction of a nitrogen atom into the skeleton, e. g., a…”
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seco-1-Azacubane-2-carboxylic Acid: Derivative Scope and Comparative Biological Evaluation by Kong, Dehui, Fahrenhorst-Jones, Tyler, Kuo, Andy, Simmons, Jacinta L., Tan, Lendl, Burns, Jed M., Pierens, Gregory K., Li, Rui, West, Nicholas P., Boyle, Glen M., Smith, Maree T., Savage, G. Paul, Williams, Craig M.

“…The unusual and sterically constrained amino acid, seco-1-azacubane-2-carboxylic acid, was incorporated into a range of bioactive chemical templates, including…”
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Dynamic NMR and Computational Studies Inform the Conformational Description of Dendrillane Terpenes from the Nudibranch Goniobranchus coi by Forster, Louise C, Pierens, Gregory K, Clegg, Jack K, Garson, Mary J

“…Two new oxygenated terpenes (1 and 2) have been characterized from the Australian nudibranch Goniobranchus coi. Broadened 1H NMR signals, together with the…”
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Activation of Natural Products Biosynthetic Pathways via a Protein Modification Level Regulation by Zhang, Benyin, Tian, Wenya, Wang, Shuwen, Yan, Xiaoli, Jia, Xinying, Pierens, Gregory K, Chen, Wenqing, Ma, Hongmin, Deng, Zixin, Qu, Xudong

“…Natural products are critical for drug discovery and development; however their discovery is challenged by the wide inactivation or silence of microbial…”
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Chemical constituents from Macleaya cordata (Willd) R. Br. and their phenotypic functions against a Parkinson’s disease patient-derived cell line by Nguyen, Duy Thanh, Iqbal, Jamila, Han, Jianying, Pierens, Gregory K., Wood, Stephen A., Mellick, George D., Feng, Yunjiang

“…[Display omitted] Cytological profiling (CP) assay against a human olfactory neuroshpere-derived (hONS) cell line using a library of traditional Chinese…”
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Isolation and In Vitro and In Vivo Activity of Secondary Metabolites from Clerodendrum polycephalum Baker against Plasmodium Malaria Parasites by Tamuli, Roktima, Nguyen, Thanh, Macdonald, Jacinta R., Pierens, Gregory K., Fisher, Gillian M., Andrews, Katherine T., Adewoyin, Francis B., Omisore, Nusrat O., Odaibo, Alexander B., Feng, Yunjiang

“…Chemical investigation of the antimalarial medicinal plant Clerodendrum polycephalum led to the isolation of five new diterpenoids, including ajugarins VII–X…”
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Austrobuxusin N, a new picrotoxane terpenoid glycoside, from the Australian endemic plant Austrobuxus swainii (Beuzev. & C.T. White) Airy Shaw by Zhang, Jiayu, Nguyen, Duy Thanh, Pierens, Gregory K., Cock, Ian, Feng, Yunjiang

“…A new picrotoxane terpenoid glycoside, austrobuxusin N (1), together with four known compounds, austrobuxusin A-D (2-5), were isolated from the leaves of the…”
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1-Azahomocubane by Fahrenhorst-Jones, Tyler, Marshall, David L, Burns, Jed. M, Pierens, Gregory K, Hormann, Robert E, Fisher, Allison M, Bernhardt, Paul V, Blanksby, Stephen J, Savage, G. Paul, Eaton, Philip E, Williams, Craig M

“…Highly strained cage hydrocarbons have long stood as fundamental molecules to explore the limits of chemical stability and reactivity, probe physical…”
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The curious case of the colored crystals of N‐substituted 2‐oxo‐1,2‐dihydropyridinyl‐3‐yl amines and amides: Self‐association in the solid state by Loughlin, Wendy A., Jenkins, Ian D., Healy, Peter C., Karis, N. David, Pierens, Gregory K.

“…During a previous investigation of pyridone derivatives as inhibitors of glycogen phosphorylase, we observed that some N‐substituted…”
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Synthesis, isolation and characterisation of fluorinated‐benzimidazoisoquinoline regioisomers by Lim, Ting Xiang, Pierens, Gregory K., Bernhardt, Paul V., Ahamed, Muneer, Reutens, David C.

“…A pair of novel fluorinated‐benzimidazoisoquinoline regioisomers was synthesised and isolated. Initial structural characterisation and identification employed…”
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Elucidation of Relative and Absolute Configurations of Highly Rearranged Diterpenoids and Evidence for a Putative Biosynthetic Intermediate from the Australian Nudibranch Goniobranchus geometricus by Forster, Louise C, Pierens, Gregory K, Garson, Mary J

“…A diterpene (1), previously isolated from a Japanese marine sponge, together with two undescribed (2, 3) diterpenes with highly rearranged carbon skeletons…”
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Meeting the Challenge 2: Identification of Potential Chemical Probes for Parkinson’s Disease from Ligusticum chuanxiong Hort Using Cytological Profiling by Miao, William Gang, Nguyen, Thanh, Iqbal, Jamila, Pierens, Gregory K., Ma, Linlin, Richardson, Des R., Wood, Stephen A., Mellick, George D., Quinn, Ronald J., Feng, Yunjiang

“…Traditional Chinese medicine (TCM) has been around for thousands of years and is increasingly gaining popularity in the Western world to treat various complex…”
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Synthetic Tigliane Intermediates Engage Thiols to Induce Potent Cell Line Selective Anti‐Cancer Activity by Chow, Sharon, Krainz, Tanja, Bettencourt, Christian J., Broit, Natasa, Ferguson, Blake, Zhu, Mingzhao, Hull, Kenneth G., Pierens, Gregory K., Bernhardt, Paul V., Parsons, Peter G., Romo, Daniel, Boyle, Glen M., Williams, Craig M.

“…The tigliane ring system, which encompasses iconic members such as phorbol and TPA, is widely renowned due to numerous observations of displaying potent…”
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