Search Results - "Pierce, Marsha L"

Sensational MicroRNAs: Neurosensory Roles of the MicroRNA-183 Family by Banks, Samantha A., Pierce, Marsha L., Soukup, Garrett A.

“…MicroRNAs (miRNAs, miRs) are short noncoding RNAs that act to repress expression of proteins from target mRNA transcripts. miRNAs influence many cellular…”
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Marine pharmacology in 2018: Marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis and antiviral activities; affecting the immune and nervous systems, and other miscellaneous mechanisms of action by Mayer, Alejandro M.S., Pierce, Marsha L., Howe, Katelyn, Rodríguez, Abimael D., Taglialatela-Scafati, Orazio, Nakamura, Fumiaki, Fusetani, Nobuhiro

“…The 2018 marine pharmacology literature review represents a continuation of the previous 11 reviews of a series initiated in 1998. Preclinical marine…”
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Comparison of the pharmacological profiles of arginine vasopressin and oxytocin analogs at marmoset, macaque, and human vasopressin 1a receptor by Pierce, Marsha L., French, Jeffrey A., Murray, Thomas F.

“…[Display omitted] Arginine vasopressin (AVP) and oxytocin (OT) are nonapeptides that bind to G-protein coupled receptors and influence social behaviors…”
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Marine Pharmacology in 2019-2021: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis and Antiviral Activities; Affecting the Immune and Nervous Systems, and Other Miscellaneous Mechanisms of Action by Mayer, Alejandro M S, Mayer, Veronica A, Swanson-Mungerson, Michelle, Pierce, Marsha L, Rodríguez, Abimael D, Nakamura, Fumiaki, Taglialatela-Scafati, Orazio

“…The current 2019-2021 marine pharmacology literature review provides a continuation of previous reviews covering the period 1998 to 2018. marine pharmacology…”
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Antillatoxin-Stimulated Neurite Outgrowth Involves the Brain-Derived Neurotrophic Factor (BDNF) - Tropomyosin Related Kinase B (TrkB) Signaling Pathway by Mehrotra, Suneet, Pierce, Marsha L, Cao, Zhengyu, Jabba, Sairam V, Gerwick, William H, Murray, Thomas F

“…Voltage-gated sodium channel (VGSC) activators promote neurite outgrowth by augmenting intracellular Na+ concentration ([Na+]i) and upregulating…”
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Stimulation of Neurite Outgrowth in Cerebrocortical Neurons by Sodium Channel Activator Brevetoxin-2 Requires Both N-Methyl-D-aspartate Receptor 2B (GluN2B) and p21 Protein (Cdc42/Rac)-Activated Kinase 1 (PAK1) by Mehrotra, Suneet, Pierce, Marsha L, Dravid, Shashank M, Murray, Thomas F

“…N-methyl-D-aspartate (NMDA) receptors play a critical role in activity-dependent dendritic arborization, spinogenesis, and synapse formation by stimulating…”
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Comparison of the pharmacologic profiles of arginine vasopressin and oxytocin analogs at marmoset, titi monkey, macaque, and human oxytocin receptors by Pierce, Marsha L., French, Jeffrey A., Murray, Thomas F.

“…[Display omitted] The oxytocin-arginine vasopressin (OT-AVP) ligand-receptor family influences a variety of physiological, behavioral, and social behavioral…”
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Epicortical Brevetoxin Treatment Promotes Neural Repair and Functional Recovery after Ischemic Stroke by Sequeira, Erica, Pierce, Marsha L, Akasheh, Dina, Sellers, Stacey, Gerwick, William H, Baden, Daniel G, Murray, Thomas F

“…Emerging literature suggests that after a stroke, the peri-infarct region exhibits dynamic changes in excitability. In rodent stroke models, treatments that…”
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MicroRNA‐183 family expression in hair cell development and requirement of microRNAs for hair cell maintenance and survival by Weston, Michael D., Pierce, Marsha L., Jensen‐Smith, Heather C., Fritzsch, Bernd, Rocha‐Sanchez, Sonia, Beisel, Kirk W., Soukup, Garrett A.

“…MicroRNAs (miRNAs) post‐transcriptionally repress complementary target gene expression and can contribute to cell differentiation. The coordinate expression of…”
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Residual microRNA expression dictates the extent of inner ear development in conditional Dicer knockout mice by Soukup, Garrett A., Fritzsch, Bernd, Pierce, Marsha L., Weston, Michael D., Jahan, Israt, McManus, Michael T., Harfe, Brian D.

“…Inner ear development requires coordinated transformation of a uniform sheet of cells into a labyrinth with multiple cell types. While numerous regulatory…”
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A mouse model of miR-96, miR-182 and miR-183 misexpression implicates miRNAs in cochlear cell fate and homeostasis by Weston, Michael D., Tarang, Shikha, Pierce, Marsha L., Pyakurel, Umesh, Rocha-Sanchez, Sonia M., McGee, JoAnn, Walsh, Edward J., Soukup, Garrett A.

“…Germline mutations in Mir96 , one of three co-expressed polycistronic miRNA genes ( Mir96, Mir182, Mir183 ), cause hereditary hearing loss in humans and mice…”
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MicroRNA-183 family conservation and ciliated neurosensory organ expression by Pierce, Marsha L, Weston, Michael D, Fritzsch, Bernd, Gabel, Harrison W, Ruvkun, Gary, Soukup, Garrett A

“…MicroRNAs (miRNAs) are an integral component of the metazoan genome and affect posttranscriptional repression of target messenger RNAs. The extreme…”
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Pagoamide A, a Cyclic Depsipeptide Isolated from a Cultured Marine Chlorophyte, Derbesia sp., Using MS/MS-Based Molecular Networking by Li, Yueying, Yu, Hao-Bing, Zhang, Yi, Leao, Tiago, Glukhov, Evgenia, Pierce, Marsha L, Zhang, Chen, Kim, Hyunwoo, Mao, Huanru Henry, Fang, Fang, Cottrell, Garrison W, Murray, Thomas F, Gerwick, Lena, Guan, Huashi, Gerwick, William H

“…A thiazole-containing cyclic depsipeptide with 11 amino acid residues, named pagoamide A (1), was isolated from laboratory cultures of a marine Chlorophyte,…”
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The 2021 Marine Pharmacology and Pharmaceuticals Pipeline by Wu, Alex C., Jelielek, Karolina K., Le, Henry Q., Butt, Maryam, Newman, David J., Glaser, Keith B., Pierce, Marsha L., Mayer, Alejandro M.

“…Objective Marine organisms continue providing significant chemical biodiversity that contributes to both the global preclinical and clinical pharmaceutical…”
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A Comparison of the Ability of Leu 8 - and Pro 8 -Oxytocin to Regulate Intracellular Ca 2+ and Ca 2+ -Activated K + Channels at Human and Marmoset Oxytocin Receptors by Pierce, Marsha L, Mehrotra, Suneet, Mustoe, Aaryn C, French, Jeffrey A, Murray, Thomas F

“…The neurohypophyseal hormone oxytocin (OT) regulates biologic functions in both peripheral tissues and the central nervous system. In the central nervous…”
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Heterologous Expression in Anabaena of the Columbamide Pathway from the Cyanobacterium Moorena bouillonii and Production of New Analogs by Taton, Arnaud, Rohrer, Sebastian, Diaz, Brienna, Reher, Raphael, Caraballo Rodriguez, Andres Mauricio, Pierce, Marsha L., Dorrestein, Pieter C., Gerwick, Lena, Gerwick, William H., Golden, James W.

“…Columbamides are chlorinated acyl amide natural products, several of which exhibit cannabinomimetic activity. These compounds were originally discovered from a…”
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Discovery and Synthesis of Caracolamide A, an Ion Channel Modulating Dichlorovinylidene Containing Phenethylamide from a Panamanian Marine Cyanobacterium cf. Symploca Species by Naman, C. Benjamin, Almaliti, Jehad, Armstrong, Lorene, Caro-Díaz, Eduardo J, Pierce, Marsha L, Glukhov, Evgenia, Fenner, Amanda, Spadafora, Carmenza, Debonsi, Hosana M, Dorrestein, Pieter C, Murray, Thomas F, Gerwick, William H

“…A recent untargeted metabolomics investigation into the chemical profile of 10 organic extracts from cf. Symploca spp. revealed several interesting chemical…”
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MicroRNA gene expression in the mouse inner ear by Weston, Michael D., Pierce, Marsha L., Rocha-Sanchez, Sonia, Beisel, Kirk W., Soukup, Garrett A.

“…MicroRNAs (miRNAs) are small non-coding RNAs that function through the RNA interference (RNAi) pathway and post-transcriptionally regulate gene expression in…”
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Treating Traumatic Brain Injuries with Electroceuticals: Implications for the Neuroanatomy of Consciousness by Aburas, Jihad, Aziz, Areej, Butt, Maryam, Leschinsky, Angela, Pierce, Marsha L.

“…According to the Centers for Disease Control and Prevention (CDC), traumatic brain injury (TBI) is the leading cause of loss of consciousness, long-term…”
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Conditional deletion of the human ortholog gene Dicer1 in Pax2-Cre expression domain impairs orofacial development by Barritt, Laura, Miller, Joseph, Scheetz, Laura, Gardner, Kelsey, Pierce, Marsha, Soukup, Garrett, Rocha-Sanchez, Sonia

“…Background: Orofacial clefts are common worldwide and result from insufficient growth and/or fusion during the genesis of the derivatives of the first…”
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