Search Results - "Pieper, Carl"
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Soluble Macrophage Biomarkers Indicate Inflammatory Phenotypes in Patients With Knee Osteoarthritis
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-04-2015)“…Objective To evaluate the ability of the macrophage markers CD163 and CD14 to predict different osteoarthritis (OA) phenotypes defined by severity of joint…”
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Change in the Rate of Biological Aging in Response to Caloric Restriction: CALERIE Biobank Analysis
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-01-2018)“…Abstract Biological aging measures have been proposed as proxies for extension of healthy life span in trials of geroprotective therapies that aim to slow…”
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A metabolomics comparison of plant-based meat and grass-fed meat indicates large nutritional differences despite comparable Nutrition Facts panels
Published in Scientific reports (05-07-2021)“…A new generation of plant-based meat alternatives—formulated to mimic the taste and nutritional composition of red meat—have attracted considerable consumer…”
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2 years of calorie restriction and cardiometabolic risk (CALERIE): exploratory outcomes of a multicentre, phase 2, randomised controlled trial
Published in The lancet. Diabetes & endocrinology (01-09-2019)“…For several cardiometabolic risk factors, values considered within normal range are associated with an increased risk of cardiovascular morbidity and…”
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Associations Between Traumatic Brain Injury and Cognitive Decline Among Older Male Veterans: A Twin Study
Published in Neurology (31-10-2023)“…Traumatic brain injuries (TBIs) are associated with increased risk of dementia, but whether lifetime TBI influences cognitive trajectories in later life is…”
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Association of traumatic brain injury with subsequent neurological and psychiatric disease: a meta-analysis
Published in Journal of neurosurgery (01-02-2016)“…Mild traumatic brain injury (TBI) has been proposed as a risk factor for the development of Alzheimer's disease, Parkinson's disease, depression, and other…”
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Mitigation behavior prior to COVID-19 vaccination availability is associated with COVID-19 infection and time to vaccination
Published in PloS one (24-03-2023)“…Mitigation behaviors reduce the incidence of COVID-19 infection. Determining characteristics of groups defined by mitigation behaviors compliance may be useful…”
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Changes in body weight, adherence, and appetite during 2 years of calorie restriction: the CALERIE 2 randomized clinical trial
Published in European journal of clinical nutrition (01-08-2020)“…Background/objectives The Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy Phase 2 (CALERIE) study showed that individuals who are…”
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Effect of Calorie Restriction on Mood, Quality of Life, Sleep, and Sexual Function in Healthy Nonobese Adults: The CALERIE 2 Randomized Clinical Trial
Published in JAMA internal medicine (01-06-2016)“…Calorie restriction (CR) increases longevity in many species and reduces risk factors for chronic diseases. In humans, CR may improve health span, yet concerns…”
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Accelerometer‐Measured Hospital Physical Activity and Hospital‐Acquired Disability in Older Adults
Published in Journal of the American Geriatrics Society (JAGS) (01-02-2020)“…BACKGROUND Hospital‐acquired disability (HAD) is common and often related to low physical activity while in the hospital. OBJECTIVE To examine whether wearable…”
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Effects of 2 years of caloric restriction on oxidative status assessed by urinary F2‐isoprostanes: The CALERIE 2 randomized clinical trial
Published in Aging cell (01-04-2018)“…Summary Calorie restriction (CR) without malnutrition slows aging in animal models. Oxidative stress reduction was proposed to mediate CR effects. CR effect on…”
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Identifying Patterns of Multimorbidity in Older Americans: Application of Latent Class Analysis
Published in Journal of the American Geriatrics Society (JAGS) (01-08-2016)“…Objectives To define multimorbidity “classes” empirically based on patterns of disease co‐occurrence in older Americans and to examine how class membership…”
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Effect of Two‐Year Caloric Restriction on Bone Metabolism and Bone Mineral Density in Non‐Obese Younger Adults: A Randomized Clinical Trial
Published in Journal of bone and mineral research (01-01-2016)“…ABSTRACT Although caloric restriction (CR) could delay biologic aging in humans, it is unclear if this would occur at the cost of significant bone loss. We…”
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Quantification of the pace of biological aging in humans through a blood test, the DunedinPoAm DNA methylation algorithm
Published in eLife (05-05-2020)“…Biological aging is the gradual, progressive decline in system integrity that occurs with advancing chronological age, causing morbidity and disability…”
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Long-term moderate calorie restriction inhibits inflammation without impairing cell-mediated immunity: a randomized controlled trial in non-obese humans
Published in Aging (Albany, NY.) (01-07-2016)“…Calorie restriction (CR) inhibits inflammation and slows aging in many animal species, but in rodents housed in pathogen-free facilities, CR impairs immunity…”
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Warrior Wellness: A Randomized Controlled Pilot Trial of the Effects of Exercise on Physical Function and Clinical Health Risk Factors in Older Military Veterans With PTSD
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-11-2020)“…Abstract Background Military veterans living with post-traumatic stress disorder (PTSD) face significant physical and functional health disparities, which are…”
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Pilot randomized controlled trial of exercise training for older veterans with PTSD
Published in Journal of behavioral medicine (01-08-2020)“…Exercise training positively impacts mental health, yet remains untested in older adults with posttraumatic stress disorder (PTSD). We conducted a randomized…”
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Traumatic brain injury and dementia risk in male veteran older twins—Controlling for genetic and early life non‐genetic factors
Published in Alzheimer's & dementia (01-11-2022)“…Introduction This study leveraged the twin study design, which controls for shared genetic and early life exposures, to investigate the association between…”
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Effects of caloric restriction on human physiological, psychological, and behavioral outcomes: highlights from CALERIE phase 2
Published in Nutrition reviews (01-01-2021)“…Abstract Caloric restriction (CR) is a strategy that attenuates aging in multiple nonhuman species. The Comprehensive Assessment of Long-term Effects of…”
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Exploration of model misspecification in latent class methods for longitudinal data: Correlation structure matters
Published in Statistics in medicine (30-06-2023)“…Modeling longitudinal trajectories and identifying latent classes of trajectories is of great interest in biomedical research, and software to identify latent…”
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