Search Results - "Piel, G."

In vitro skin penetration enhancement techniques: A combined approach of ethosomes and microneedles by Bellefroid, C., Lechanteur, A., Evrard, B., Mottet, D., Debacq-Chainiaux, F., Piel, G.

“…[Display omitted] Dermal administration of different macromolecules, such as nucleic acids, remains a real challenge because of the difficulty of crossing the…”
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Systematic study of liposomes composition towards efficient delivery of plasmid DNA as potential application of dermal fibroblasts targeting by Bellefroid, C., Reusch, C., Lechanteur, A., Evrard, B., Debacq-Chainiaux, F., Mottet, D., Piel, G.

“…[Display omitted] The use of non-viral DNA vectors to topically treat skin diseases has demonstrated a high potential. However, vectors applied on the skin…”
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Nuclear delivery of a therapeutic peptide by long circulating pH-sensitive liposomes: Benefits over classical vesicles by Ducat, E., Deprez, J., Gillet, A., Noël, A., Evrard, B., Peulen, O., Piel, G.

“…The purpose of this study is to propose a suitable vector combining increased circulation lifetime and intracellular delivery capacities for a therapeutic…”
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Liposome surface charge influence on skin penetration behaviour by Gillet, A., Compère, P., Lecomte, F., Hubert, P., Ducat, E., Evrard, B., Piel, G.

“…Vesicular systems have shown their ability to increase dermal and transdermal drug delivery. Their mechanism of drug transport into and through the skin has…”
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Skin penetration behaviour of liposomes as a function of their composition by Gillet, A., Lecomte, F., Hubert, P., Ducat, E., Evrard, B., Piel, G.

“…Schematic representation of fluorescently labelled liposomes encapsulating calcein in their inner cavity (A), liposomes encapsulating NBD-PC in their lipid…”
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Development of a new topical system: Drug-in-cyclodextrin-in-deformable liposome by Gillet, A., Grammenos, A., Compère, P., Evrard, B., Piel, G.

“…A new delivery system for cutaneous administration combining the advantages of cyclodextrin inclusion complexes and those of deformable liposomes was…”
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Systematic characterization of oil-in-water emulsions for formulation design by Roland, I., Piel, G., Delattre, L., Evrard, B.

“…Oil-in-water emulsions varying in surfactant concentration and manufacturing process were prepared. About 10 experiments were performed to characterize them…”
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Determination of 4-aminophenol in a pharmaceutical formulation using surface enhanced Raman scattering: From development to method validation by De Bleye, C., Dumont, E., Rozet, E., Sacré, P.-Y., Chavez, P.-F., Netchacovitch, L., Piel, G., Hubert, Ph, Ziemons, E.

“…A surface enhanced Raman scattering (SERS) method able to quantify 4-aminophenol in a pharmaceutical formulation based on acetaminophen, also called…”
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Development of a quantitative approach using surface-enhanced Raman chemical imaging: First step for the determination of an impurity in a pharmaceutical model by De Bleye, C., Sacré, P.-Y., Dumont, E., Netchacovitch, L., Chavez, P.-F., Piel, G., Lebrun, P., Hubert, Ph, Ziemons, E.

“…•First development of a quantitative approach on a pharmaceutical model using SER-CI.•Quantification of an impurity at concentrations around its limit of…”
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Comparison of chitosan/siRNA and trimethylchitosan/siRNA complexes behaviour in vitro by Dehousse, V., Garbacki, N., Jaspart, S., Castagne, D., Piel, G., Colige, A., Evrard, B.

“…Chitosan and trimethylchitosan (TMC)-siRNA nanoparticles were produced by simple complexation technique or by ionic gelation using tripolyphosphate (TPP). The…”
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Study of the relationship between lipid binding properties of cyclodextrins and their effect on the integrity of liposomes by Piel, G., Piette, M., Barillaro, V., Castagne, D., Evrard, B., Delattre, L.

“…It is well known that cyclodextrins are able to extract lipids constituting membranes, increasing their fluidity and permeability. This behaviour towards…”
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Betamethasone-in-cyclodextrin-in-liposome: The effect of cyclodextrins on encapsulation efficiency and release kinetics by Piel, Géraldine, Piette, Marie, Barillaro, Valery, Castagne, Delphine, Evrard, Brigitte, Delattre, Luc

“…Lipophilic drugs have limited solubility in phospholipid systems, hence maximum entrapment levels in liposomes are known to be low…”
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Quantification of Randomly-methylated-β-cyclodextrin effect on liposome: An ESR study by Grammenos, A., Bahri, M.A., Guelluy, P.H., Piel, G., Hoebeke, M.

“…In the present work, the effect of Randomly-methylated-β-cyclodextrin (Rameb) on the microviscosity of dimyristoyl- l-α phosphatidylcholine (DMPC) bilayer was…”
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ESR technique for noninvasive way to quantify cyclodextrins effect on cell membranes by Grammenos, A., Mouithys-Mickalad, A., Guelluy, P.H., Lismont, M., Piel, G., Hoebeke, M.

“…► ESR: a new tool for cyclodextrins study on living cells. ► Cholesterol and phospholipid extraction by Rameb in a dose- and time-dependent way. ► Extracted…”
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Development and validation of a sensitive solid phase extraction/hydrophilic interaction liquid chromatography/mass spectrometry method for the accurate determination of glucosamine in dog plasma by Hubert, C., Houari, S., Lecomte, F., Houbart, V., De Bleye, C., Fillet, M., Piel, G., Rozet, E., Hubert, Ph

“…A sensitive and accurate LC/MS method was developed for the monitoring of glucosamine (GLcN) dog plasmatic concentration. In this scope, relatively low…”
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Cellular uptake of liposomes monitored by confocal microscopy and flow cytometry by Ducat, E., Evrard, B., Peulen, O., Piel, G.

“…For several years, two advanced techniques, confocal laser scanning microscopy (CLSM) and flow cytometry, in particular fluorescence-activated cell sorting…”
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Liposomes and parameters affecting their skin penetration behaviour by Gillet, A., Evrard, B., Piel, G.

“…It is known that classical and more recently deformable liposomes have shown their ability to increase dermal and transdermal drug delivery. However their…”
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Oral bioavailability in sheep of albendazole from a suspension and from a solution containing hydroxypropyl-β-cyclodextrin by Evrard, B, Chiap, P, DeTullio, P, Ghalmi, F, Piel, G, Van Hees, T, Crommen, J, Losson, B, Delattre, L

“…Albendazole (ABZ) is a benzimidazole derivative with a broad spectrum of activity against human and animal helminthe parasites. ABZ has a very poor aqueous…”
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Cyclodextrins as a potential carrier in drug nebulization by Evrard, B, Bertholet, P, Gueders, M, Flament, M.-P, Piel, G, Delattre, L, Gayot, A, Leterme, P, Foidart, J.-M, Cataldo, D

“…The inhalation route is widely studied for many drug applications focusing on either local or systemic distributions. One matter of concern is the…”
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Automated method for the determination of a new matrix metalloproteinase inhibitor in ovine plasma and serum by coupling of restricted access material for on-line sample clean-up to liquid chromatography by CHIAP, P, PIETTE, M, HUBERT, Ph, EVRARD, B, FRANKENNE, F, CHRISTIAENS, B, PIEL, G, CATALDO, D, FOIDART, J.-M, DELATTRE, L, CRONUNEN, J

“…A fully automated liquid chromatographic method was developed for the determination of Ro 28-2653, a new synthetic inhibitor of matrix metalloproteinases…”
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