Search Results - "Piekarz, M."

Esco1 and Esco2 regulate distinct cohesin functions during cell cycle progression by Alomer, Reem M., da Silva, Eulália M. L., Chen, Jingrong, Piekarz, Katarzyna M., McDonald, Katherine, Sansam, Courtney G., Sansam, Christopher L., Rankin, Susannah

“…Sister chromatids are tethered together by the cohesin complex from the time they are made until their separation at anaphase. The ability of cohesin to tether…”
Get full text

Specification of distinct cell types in a sensory-adhesive organ important for metamorphosis in tunicate larvae by Johnson, Christopher J, Razy-Krajka, Florian, Zeng, Fan, Piekarz, Katarzyna M, Biliya, Shweta, Rothbächer, Ute, Stolfi, Alberto

“…The papillae of tunicate larvae contribute sensory, adhesive, and metamorphosis-regulating functions that are crucial for the biphasic lifestyle of these…”
Get full text

Neuron‐specific deletion of CuZnSOD leads to an advanced sarcopenic phenotype in older mice by Bhaskaran, Shylesh, Pollock, Natalie, Macpherson, Peter, Ahn, Bumsoo, Piekarz, Katarzyna M., Staunton, Caroline A., Brown, Jacob L., Qaisar, Rizwan, Vasilaki, Aphrodite, Richardson, Arlan, McArdle, Anne, Jackson, Malcolm J., Brooks, Susan V., Van Remmen, Holly

“…Age‐associated loss of muscle mass and function (sarcopenia) has a profound effect on the quality of life in the elderly. Our previous studies show that…”
Get full text

Mitochondrial oxidative stress impairs contractile function but paradoxically increases muscle mass via fibre branching by Ahn, Bumsoo, Ranjit, Rojina, Premkumar, Pavithra, Pharaoh, Gavin, Piekarz, Katarzyna M., Matsuzaki, Satoshi, Claflin, Dennis R., Riddle, Kaitlyn, Judge, Jennifer, Bhaskaran, Shylesh, Satara Natarajan, Kavithalakshmi, Barboza, Erika, Wronowski, Benjamin, Kinter, Michael, Humphries, Kenneth M., Griffin, Timothy M., Freeman, Willard M., Richardson, Arlan, Brooks, Susan V., Van Remmen, Holly

“…Background Excess reactive oxygen species (ROS) and muscle weakness occur in parallel in multiple pathological conditions. However, the causative role of…”
Get full text

Comprehensive forecast of electromobility mid-term development in Poland and its impacts on power system demand by Piotrowski, P, Baczyński, D, Robak, S, Kopyt, M, Piekarz, M, Polewaczyk, M

“…This paper discusses three variants of how e-mobility development will affect the Polish Power System. Multivariate forecasts of annual new registrations of…”
Get full text

Cancer cachexia in a mouse model of oxidative stress by Brown, Jacob L., Lawrence, Marcus M., Ahn, Bumsoo, Kneis, Parker, Piekarz, Katarzyna M., Qaisar, Rizwan, Ranjit, Rojina, Bian, Jan, Pharaoh, Gavin, Brown, Chase, Peelor, Fredrick F., Kinter, Michael T., Miller, Benjamin F., Richardson, Arlan, Van Remmen, Holly

“…Background Cancer is associated with muscle atrophy (cancer cachexia) that is linked to up to 40% of cancer‐related deaths. Oxidative stress is a critical…”
Get full text

Age Related Changes in Muscle Mass and Force Generation in the Triple Transgenic (3xTgAD) Mouse Model of Alzheimer's Disease by Xu, Hongyang, Bhaskaran, Shylesh, Piekarz, Katarzyna M, Ranjit, Rojina, Bian, Jan, Kneis, Parker, Ellis, Aubrey, Bhandari, Suyesha, Rice, Heather C, Van Remmen, Holly

“…Emerging evidence suggests that patients with Alzheimer's disease (AD) may show accelerated sarcopenia phenotypes. To investigate whether pathological changes…”
Get full text

Neuronal deletion of MnSOD in mice leads to demyelination, inflammation and progressive paralysis that mimics phenotypes associated with progressive multiple sclerosis by Bhaskaran, Shylesh, Kumar, Gaurav, Thadathil, Nidheesh, Piekarz, Katarzyna M., Mohammed, Sabira, Lopez, Sergio Dominguez, Qaisar, Rizwan, Walton, Dorothy, Brown, Jacob L., Murphy, Ashley, Smith, Nataliya, Saunders, Debra, Beckstead, Michael J., Plafker, Scott, Lewis, Tommy L., Towner, Rheal, Deepa, Sathyaseelan S., Richardson, Arlan, Axtell, Robert C., Van Remmen, Holly

“…Neuronal oxidative stress has been implicated in aging and neurodegenerative disease. Here we investigated the impact of elevated oxidative stress induced in…”
Get full text

Rapid method for plutonium-241 determination in soil samples by Piekarz, M., Komosa, A.

“…A simple and rapid procedure for the determination of plutonium isotopes in the environment is presented. The procedure combines alpha spectrometry, solvent…”
Get full text

Development and circuitry of the tunicate larval Motor Ganglion, a putative hindbrain/spinal cord homolog by Piekarz, Katarzyna M., Stolfi, Alberto

“…The Motor Ganglion (MG) is a small collection of neurons that control the swimming movements of the tunicate tadpole larva. Situated at the base of the tail,…”
Get full text

The nitrone compound OKN-007 delays motor neuron loss and disease progression in the G93A mouse model of amyotrophic lateral sclerosis by Bhaskaran, Shylesh, Piekarz, Katarzyna M., Brown, Jacob, Yang, Brian, Ocañas, Sarah R., Wren, Jonathan D., Georgescu, Constantin, Bottoms, Christopher, Murphy, Ashley, Thomason, Jessica, Saunders, Debra, Smith, Nataliya, Towner, Rheal, Van Remmen, Holly

“…Our study investigated the therapeutic potential of OKN-007 in the SOD1 G93A mouse model of amyotrophic lateral sclerosis (ALS). The impact of OKN-007, known…”
Get full text

Specification and survival of post-metamorphic branchiomeric neurons in a non-vertebrate chordate by Gigante, Eduardo D, Piekarz, Katarzyna M, Gurgis, Alexandra, Cohen, Leslie, Razy-Krajka, Florian, Popsuj, Sydney, Johnson, Christopher J, Ali, Hussan S, Mohana Sundaram, Shruthi, Stolfi, Alberto

“…Tunicates are the sister group to the vertebrates, yet most species have a life cycle split between swimming larva and sedentary adult phases. During…”
Get more information

Scavenging mitochondrial hydrogen peroxide by peroxiredoxin 3 overexpression attenuates contractile dysfunction and muscle atrophy in a murine model of accelerated sarcopenia by Ahn, Bumsoo, Ranjit, Rojina, Kneis, Parker, Xu, Hongyang, Piekarz, Katarzyna M., Freeman, Willard M., Kinter, Michael, Richardson, Arlan, Ran, Qitao, Brooks, Susan V., Van Remmen, Holly

“…Age‐related muscle atrophy and weakness, or sarcopenia, are significant contributors to compromised health and quality of life in the elderly. While the…”
Get full text

Semivolatile Fluorinated Organic Compounds in Asian and Western U.S. Air Masses by Piekarz, Arkadiusz M, Primbs, Toby, Field, Jennifer A, Barofsky, Douglas F, Simonich, Staci

“…Semivolatile fluorinated organic compounds (FOCs) were measured in archived air sample extracts collected from Hedo Station Observatory (HSO) on Okinawa, Japan…”
Get full text

Neuroprotective treatment with the nitrone compound OKN-007 mitigates age-related muscle weakness in aging mice by Xu, Hongyang, Piekarz, Katarzyna M., Brown, Jacob L., Bhaskaran, Shylesh, Smith, Nataliya, Towner, Rheal A., Van Remmen, Holly

“…Despite the universal impact of sarcopenia on compromised health and quality of life in the elderly, promising pharmaceutical approaches that can effectively…”
Get full text

Pharmacologic treatment with OKN-007 reduces alpha-motor neuron loss in spinal cord of aging mice by Piekarz, Katarzyna M., Georgescu, Constantin, Wren, Jonathan D., Towner, Rheal A., Van Remmen, Holly

“…Aging is associated with molecular and functional declines in multiple physiologic systems. We have previously reported age-related changes in spinal cord that…”
Get full text

Senolytic treatment does not mitigate oxidative stress-induced muscle atrophy but improves muscle force generation in CuZn superoxide dismutase knockout mice by Borowik, Agnieszka K., Lawrence, Marcus M., Peelor, Frederick F., Piekarz, Katarzyna M., Crosswhite, Abby, Richardson, Arlan, Miller, Benjamin F., Van Remmen, Holly, Brown, Jacob L.

“…Oxidative stress is associated with tissue dysfunctions that can lead to reduced health. Prior work has shown that oxidative stress contributes to both muscle…”
Get full text

Molecular changes associated with spinal cord aging by Piekarz, Katarzyna M., Bhaskaran, Shylesh, Sataranatarajan, Kavithalakshmi, Street, Kaitlyn, Premkumar, Pavithra, Saunders, Debra, Zalles, Michelle, Gulej, Rafal, Khademi, Shadi, Laurin, Jaime, Peelor, Rick, Miller, Benjamin F., Towner, Rheal, Van Remmen, Holly

“…Age-related muscle weakness and loss of muscle mass (sarcopenia) is a universal problem in the elderly. Our previous studies indicate that alpha motor neurons…”
Get full text

Molecular changes in transcription and metabolic pathways underlying muscle atrophy in the CuZnSOD null mouse model of sarcopenia by Sataranatarajan, Kavithalakshmi, Pharaoh, Gavin, Brown, Jacob L., Ranjit, Rojina, Piekarz, Katarzyna M., Street, Kaitlyn, Wren, Jonathan D., Georgescu, Constantin, Kinter, Caroline, Kinter, Michael, Freeman, Willard M., Richardson, Arlan, Van Remmen, Holly

“…Mice lacking the superoxide anion scavenger CuZn superoxide dismutase ( Sod1 −/− mice) develop a number of age-related phenotypes, including an early…”
Get full text

Standards-Based Physical Education in Schools: The Role of State Laws by Sprow, Kyle, Perna, Frank M., Leider, Julien, Turner, Lindsey, Piekarz-Porter, Elizabeth M., Michael, Shannon L., Brener, Nancy, Chriqui, Jamie F.

“…Examine the association of state physical education (PE) laws (https://class.cancer.gov) with school policies addressing motor skill development, physical…”
Get full text