Effect of a global intervention in the integral control of multiple risk factors in patients at high or very high cardiovascular risk. CIFARC 2 project

To analyze the effect of a global approach on patients with high cardiovascular risk for the integral control of cardiovascular risk factors. Multicentric prospective study of patients with high vascular risk, followed-up for one year in internal medicine consultations. We measured the grade of cont...

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Bibliographic Details
Published in:	Revista clínica espanõla Vol. 207; no. 3; p. 112
Main Authors:	de la Peña Fernández, A, Roca Villanueva, B, Cuende Melero, I, Calabuig Alborch, J R, Montes Santiago, J, Muñoz Rodríguez, M, Piedracausa Selfa, M, Suárez Fernández, C
Format:	Journal Article
Language:	Spanish
Published:	Spain 01-03-2007
Subjects:	Aged Cardiovascular Agents - therapeutic use Cardiovascular Diseases - drug therapy Cardiovascular Diseases - epidemiology Cohort Studies Female Humans Male Middle Aged Prospective Studies Risk Factors Spain - epidemiology Treatment Outcome Spain
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Summary:	To analyze the effect of a global approach on patients with high cardiovascular risk for the integral control of cardiovascular risk factors. Multicentric prospective study of patients with high vascular risk, followed-up for one year in internal medicine consultations. We measured the grade of control over major cardiovascular risk factors (hypertension, dyslipidemia, diabetes mellitus, tobacco, obesity) before and after the one-year follow-up period. We studied 456 patients (56% males; age: 66.1, standard deviation: 11.5 years); 54.4% were diabetics, 58.0% had target organ damage and 46.2% had cardiovascular disease. Blood pressure control varied from 50.5 to 60.6; LDL-cholesterol control from 44.7 to 58.1%; diabetes control from 56.5 to 56.6%; tobacco control from 63.0 to 87.5% and obesity control from 60.0 to 55.4%. Integral control of all cardiovascular risk factors varied from 10.7 to 23.2% of patients. Factors independently associated to lack of integral control were: diabetes (Odds Ratio [OR]: 4.42; 95% confidence interval [95%CI]: 2.75-7.14), basal systolic blood pressure (OR: 1.03; 95%CI 1.02-1.05) and basal body mass index (OR: 1.08; 95%CI: 1.02-1.14). Lack of integral control was independently associated to the incidence of cardiovascular events (OR: 2.00; 95%CI: 1.09-5.35). A global approach on the patient with high cardiovascular risk duplicated the integral control of the five main risk factors. Diabetes and obesity were factors which made integral control difficult. Lack of integral control increased two times the risk of cardiovascular events.
ISSN:	0014-2565
DOI:	10.1157/13100222