Search Results - "Piech, Sophie"

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    Identification and Characterization of Novel Small-Molecule Enhancers of the CUL3 LZTR1 E3 Ligase KRAS Complex by Piech, Sophie, Brüschweiler, Sven, Westphalen, Josepha, Siess, Katharina M, García Murias, Julio, Konrat, Robert, Bigenzahn, Johannes W, Superti-Furga, Giulio

    Published in ACS chemical biology (20-09-2024)
    “…The RAS family of GTPases is among the most frequently mutated proteins in human cancer, creating a high clinical demand for therapies that counteract their…”
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    Journal Article
  2. 2

    Identification and Characterization of Novel Small-Molecule Enhancers of the CUL3LZTR1 E3 Ligase KRAS Complex by Piech, Sophie, Brüschweiler, Sven, Westphalen, Josepha, Siess, Katharina M., García Murias, Julio, Konrat, Robert, Bigenzahn, Johannes W., Superti-Furga, Giulio

    Published in ACS chemical biology (20-09-2024)
    “…The RAS family of GTPases is among the most frequently mutated proteins in human cancer, creating a high clinical demand for therapies that counteract their…”
    Get full text
    Journal Article