Search Results - "Pickersgill, Fraser"

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  1. 1

    Metabolism and disposition of [14C]tivantinib after oral administration to humans, dogs and rats by Murai, Takahiro, Takakusa, Hideo, Nakai, Daisuke, Kamiyama, Emi, Taira, Tomoe, Kimura, Tomoko, Jimbo, Takeshi, Bathala, Mohinder, Pickersgill, Fraser, Zahir, Hamim, Tokui, Taro, Savage, Ronald E., Ashwell, Mark A., Izumi, Takashi

    Published in Xenobiotica (01-11-2014)
    “…Abstract 1. The biotransformation and disposition of tivantinib in humans, dogs and rats was examined after a single oral administration of [14C]tivantinib…”
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    Journal Article
  2. 2

    Abstract 747: Absorption, distribution, metabolism, and excretion of 14C-Labeled tivantinib (ARQ 197) in healthy male subjects by Bathala, Mohinder S., Nakai, Daisuke, Murai, Takahiro, Pickersgill, Fraser, Zahir, Hamim, Tokui, Taro

    Published in Cancer research (Chicago, Ill.) (15-04-2012)
    “…Background: Tivantinib (ARQ 197), a selective, oral, non-ATP-competitive, small-molecule inhibitor of c-MET receptor tyrosine kinase, is being evaluated in…”
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  3. 3

    Abstract 1311: Disposition and biotransformation of [14C]-radiolabeled CS-7017 in healthy male subjects by Bathala, Mohinder, Uchiyama, Minoru, Koda, Hiroko, He, Ling, Pickersgill, Fraser, Koyama, Kumiko, Zahir, Hamim, Iwabuchi, Haruo, Izumi, Takashi, Tokui, Taro

    Published in Cancer research (Chicago, Ill.) (15-04-2011)
    “…Background: CS-7017 is a novel, oral, highly potent and selective peroxisome proliferator-activated receptor gamma agonist with demonstrated anticancer…”
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  4. 4

    Preparation of Functionalized, Conformationally Constrained DTPA Analogues from l- or d-Serine and trans-4-Hydroxy-l-proline. Hydroxymethyl Substituents on the Central Acetic Acid and on the Backbone by Pickersgill, I. Fraser, Rapoport, Henry

    Published in Journal of organic chemistry (30-06-2000)
    “…The enantio- and diastereospecific syntheses of conformationally constrained diethylenetriaminepentaacetic acid (DTPA) analogues that are functionalized with a…”
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