Search Results - "Pickavance, Lucy C."

Owner misperception of canine body condition persists despite use of a body condition score chart by Eastland-Jones, Rebekah C., German, Alexander J., Holden, Shelley L., Biourge, Vincent, Pickavance, Lucy C.

“…Canine obesity is a prevalent disease, but many owners are unaware of it, partly due to misperception of their dog's body shape. Body condition scoring (BCS)…”
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Relationships between dietary macronutrients and adult neurogenesis in the regulation of energy metabolism by Yon, Marianne A., Mauger, Suzanna L., Pickavance, Lucy C.

“…Of the environmental factors which have an impact on body weight, nutrients are most influential. Within normal limits, hypothalamic and related neuronal…”
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A fat-enriched, glucose-enriched diet markedly attenuates adiponectin mRNA levels in rat epididymal adipose tissue by Naderali, Ebrahim K, Estadella, Debora, Rocha, Milagros, Pickavance, Lucy C, Fatani, Sameer, Denis, Raphael G P, Williams, Gareth

“…Adiponectin levels are decreased in subjects with obesity, diabetes and coronary artery disease. In the present study, we have investigated whether the…”
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Activation of cells containing estrogen receptor alpha or somatostatin in the medial preoptic area, arcuate nucleus, and ventromedial nucleus of intact ewes during the follicular phase, and alteration after lipopolysaccharide by Fergani, Chrysanthi, Routly, Jean E, Jones, David N, Pickavance, Lucy C, Smith, Robert F, Dobson, Hilary

“…Cells in the medial preoptic area (mPOA), arcuate nucleus (ARC), and ventromedial nucleus (VMN) that possess estrogen receptor alpha (ER alpha) mediate…”
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Dietary obesity in the rat induces endothelial dysfunction without causing insulin resistance: a possible role for triacylglycerols by Naderali, E K, Brown, M J, Pickavance, L C, Wilding, J P, Doyle, P J, Williams, G

“…Impaired arterial vasorelaxation, due primarily to endothelial dysfunction, is associated with obesity. To clarify the relationship with insulin resistance and…”
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Differential vascular dysfunction in response to diets of differing macronutrient composition: a phenomenonological study by Fatani, Sameer, Pickavance, Lucy C, Sadler, Claire J, Harrold, Joanne A, Cassidy, Roslyn, Wilding, John Ph, Naderali, Ebrahim K

“…Vascular dysfunction can develop from consumption of an energy-rich diet, even prior to the onset of obesity. However, the roles played by different dietary…”
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Relationships between dietary macronutrients and adult neurogenesis in the regulation of energy metabolism – CORRIGENDUM by Yon, Marianne A., Mauger, Suzanna L., Pickavance, Lucy C.

“…Of the environmental factors which have an impact on body weight, nutrients are most influential. Within normal limits, hypothalamic and related neuronal…”
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Activation of Cells Containing Estrogen Receptor Alpha or Somatostatin in the Medial Preoptic Area, Arcuate Nucleus, and Ventromedial Nucleus of Intact Ewes During the Follicular Phase, and Alteration after Lipopolysaccharide1 by Fergani, Chrysanthi, Routly, Jean E, Jones, David N, Pickavance, Lucy C, Smith, Robert F, Dobson, Hilary

“…Cells in the medial preoptic area (mPOA), arcuate nucleus (ARC), and ventromedial nucleus (VMN) that possess estrogen receptor alpha (ER alpha) mediate…”
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The dual PPARα/γ agonist, ragaglitazar, improves insulin sensitivity and metabolic profile equally with pioglitazone in diabetic and dietary obese ZDF rats by Pickavance, Lucy C, Brand, Christian L, Wassermann, Karsten, Wilding, John P H

“…1 In 6‐ and 10‐week‐old obesity‐prone (fa/fa) Zucker diabetic fatty (ZDF) rats, effects of prevention and intervention therapies, respectively, were compared…”
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Diet-induced endothelial dysfunction in the rat is independent of the degree of increase in total body weight by Naderali, E K, Pickavance, L C, Wilding, J P, Williams, G

“…A growing number of studies indicate an association between obesity, insulin resistance, dyslipidaemia and cardiovascular disorders, collectively known as…”
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Chronic treatment with the thiazolidinedione, MCC-555, is associated with reductions in nitric oxide synthase activity and β-cell apoptosis in the pancreas of the Zucker Diabetic Fatty rat by Pickavance, Lucy C., Widdowson, Peter S., Foster, John R., Williams, Gareth, Wilding, John P. H.

“…The Zucker Diabetic Fatty (ZDF) rat is a model of impaired insulin sensitivity arising from hyperphagia owing to a mutation in the leptin receptor. In time,…”
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Troglitazone corrects metabolic changes but not vascular dysfunction in dietary-obese rats by Naderali, Ebrahim K, Pickavance, Lucy C, Wilding, John P.H, Doyle, Patrick J, Williams, Gareth

“…Insulin resistance has been attributed to the defect in vascular function associated with obesity, type 2 diabetes and dyslipidaemia. We have investigated…”
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Distributions and colocalization of neuropeptide Y and somatostatin in the goldfish brain by Pickavance, L C, Staines, W A, Fryer, J N

“…The distributions of single- and double-labelled neuropeptide Y- (NPY-) and somatostatin-immunoreactive (SOM-IR) perikarya and processes were determined in the…”
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Effects of S 15511, a therapeutic metabolite of the insulin-sensitizing agent S 15261, in the Zucker Diabetic Fatty rat by Pickavance, L. C., Wilding, J. P. H.

“…Aim:  S 15261 is a novel oral antihyperglycaemic drug with both insulin secretagogue and insulin‐sensitizing effects. The study was designed to determine the…”
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Energy restriction enhances therapeutic efficacy of the PPARγ agonist, rosiglitazone, through regulation of visceral fat gene expression by Moore, G.B.T, Pickavance, L.C, Briscoe, C.P, Clapham, J.C, Buckingham, R.E, Wilding, J.P.H

“…Consumption of a palatable diet can induce hyperphagia, leading to weight gain (dietary obesity) and insulin resistance in rats. Thiazolidinediones (TZDs) can…”
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The dual PPAR[alpha]/[gamma] agonist, ragaglitazar, improves insulin sensitivity and metabolic profile equally with pioglitazone in diabetic and dietary obese ZDF rats by Pickavance, Lucy C, Brand, Christian L, Wassermann, Karsten, Wilding, John P H

“…In 6- and 10-week-old obesity-prone (fa/fa) Zucker diabetic fatty (ZDF) rats, effects of prevention and intervention therapies, respectively, were compared…”
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The dual PPARalpha/gamma agonist, ragaglitazar, improves insulin sensitivity and metabolic profile equally with pioglitazone in diabetic and dietary obese ZDF rats by Pickavance, Lucy C, Brand, Christian L, Wassermann, Karsten, Wilding, John P H

“…In 6- and 10-week-old obesity-prone (fa/fa) Zucker diabetic fatty (ZDF) rats, effects of prevention and intervention therapies, respectively, were compared…”
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Neuropeptide Y receptor alterations in the hypothalamus of lactating rats by Pickavance, Lucy C., Widdowson, Peter S., Vernon, Richard G., Williams, Gareth

“…Hypothalamic neuropeptide Y (NPY) neurons are influenced by circulating levels of insulin and leptin and are thought to be involved in mediating hunger…”
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