Search Results - "Pickar, James H"

Independent conclusions? by Pickar, James H.

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Back to the future: Hormone replacement therapy as part of a prevention strategy for women at the onset of menopause by Lobo, Roger A, Pickar, J.H, Stevenson, J.C, Mack, W.J, Hodis, H.N

“…Abstract In the late 1980s, several observational studies and meta-analyses suggested that hormone replacement therapy (HRT) was beneficial for prevention of…”
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Endometrial effects of a tissue selective estrogen complex containing bazedoxifene/conjugated estrogens as a menopausal therapy by Pickar, James H., M.D, Yeh, I-Tien, M.D, Bachmann, Gloria, M.D, Speroff, Leon, M.D

“…Objective To evaluate the endometrial safety of a tissue selective estrogen complex (TSEC; pairing of a selective estrogen receptor modulator [SERM] with…”
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Efficacy of tissue-selective estrogen complex of bazedoxifene/conjugated estrogens for osteoporosis prevention in at-risk postmenopausal women by Lindsay, Robert, Ph.D, Gallagher, J. Christopher, M.D, Kagan, Risa, M.D, Pickar, James H., M.D, Constantine, Ginger, M.D

“…Objective To evaluate the efficacy of the tissue-selective estrogen complex, bazedoxifene/conjugated estrogens (BZA/CE), for postmenopausal osteoporosis…”
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Evaluation of bazedoxifene/conjugated estrogens for the treatment of menopausal symptoms and effects on metabolic parameters and overall safety profile by Lobo, Rogerio A., M.D, Pinkerton, JoAnn V., M.D, Gass, Margery L.S., M.D, Dorin, Maxine H., M.D, Ronkin, Sheila, M.D, Pickar, James H., M.D, Constantine, Ginger, M.D

“…Objective To evaluate the effects of a tissue-selective estrogen complex (TSEC) composed of bazedoxifene/conjugated estrogens (BZA/CE) on menopausal symptoms,…”
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Bazedoxifene/conjugated estrogens (BZA/CE): incidence of uterine bleeding in postmenopausal women by Archer, David F., M.D, Lewis, Vivian, M.D, Carr, Bruce R., M.D, Olivier, Sophie, M.D, Pickar, James H., M.D

“…Objective To evaluate the effect of bazedoxifene/conjugated estrogens (BZA/CE), a tissue selective estrogen complex, on uterine bleeding in postmenopausal…”
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A double-blind, randomly assigned, placebo-controlled study of desvenlafaxine efficacy and safety for the treatment of vasomotor symptoms associated with menopause by Archer, David F., MD, Seidman, Larry, DO, Constantine, Ginger D., MD, Pickar, James H., MD, Olivier, Sophie, MD

“…Objective The objective of the study was to assess the efficacy and safety of desvenlafaxine (administered as desvenlafaxine succinate) for menopausal…”
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Desvenlafaxine for the treatment of vasomotor symptoms associated with menopause: a double-blind, randomized, placebo-controlled trial of efficacy and safety by Archer, David F., MD, Dupont, Caroline M., MD, Constantine, Ginger D., MD, Pickar, James H., MD, Olivier, Sophie, MD

“…Objective The objective of the study was to assess the efficacy and safety of desvenlafaxine (administered as desvenlafaxine succinate) for the treatment of…”
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Tissue selective estrogen complex (TSEC): a review by Pickar, James H, Boucher, Matthieu, Morgenstern, Diana

“…OBJECTIVE:This review describes historical development of selective estrogen receptor modulators (SERMs) and their combination with estrogens, termed a tissue…”
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Selective estrogen receptor modulators (SERMs): A review of clinical data by Mirkin, Sebastian, Pickar, James H

“…Abstract SERMs represent a diverse group of molecules with varying levels of estrogenic agonist and antagonist activity in target tissues. SERMs have a long…”
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Endometrial effects of bazedoxifene acetate, a novel selective estrogen receptor modulator, in postmenopausal women by RONKIN, Sheila, NORTHINGTON, Robert, BARACAT, Edmund, NUNES, Marcia G, ARCHER, David F, CONSTANTINE, Ginger, PICKAR, James H

“…To assess the endometrial effects of bazedoxifene acetate in healthy postmenopausal women. The endometrial effects of bazedoxifene 2.5, 5.0, 10, 20, 30, and 40…”
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Patient considerations in the management of menopausal symptoms: role of conjugated estrogens with bazedoxifene by Kagan, Risa, Goldstein, Steven R, Pickar, James H, Komm, Barry S

“…Menopausal symptoms (eg, hot flushes and vaginal symptoms) are common, often bothersome, and can adversely impact women's sexual functioning, relationships,…”
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Progesterone by Pickar, James H.

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Conflicts of interest and the ICMJE disclosure form by Pickar, James H.

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Publishing in Climacteric by Pickar, James H.

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Molecular clustering of endometrial carcinoma based on estrogen-induced gene expression by Westin, Shannon N., Broaddus, Russell R., Deng, Lei, McCampbell, Adrienne, Lu, Karen H., Lacour, Robin A., Milam, Michael R., Urbauer, Diana L., Mueller, Peter, Pickar, James H., Loose, David S.

“…Identification of biomarkers potentially provides prognostic information that can help guide clinical decision-making.  Given the relationship between estrogen…”
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Body composition during treatment with conjugated estrogens with and without medroxyprogesterone acetate: analysis of the women’s Health, Osteoporosis, Progestin, Estrogen (HOPE) trial by Thorneycroft, Ian H., MD, PhD, Lindsay, Robert, MBChB, PhD, Pickar, James H., MD

“…Objective The objective of the study was to determine the effects of several doses of conjugated estrogens (CE) and CE plus medroxyprogesterone acetate (MPA)…”
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SERMs: Progress and future perspectives by Pickar, James H, MacNeil, Tanya, Ohleth, Kathleen

“…Abstract Selective estrogen receptor modulators (SERMs) interact with estrogen receptors as agonists or antagonists depending on the target tissue. Currently…”
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The response to ospemifene in normal human breast tissue cultures by Pickar, James H

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The REJOICE trial: a phase 3 randomized, controlled trial evaluating the safety and efficacy of a novel vaginal estradiol soft-gel capsule for symptomatic vulvar and vaginal atrophy by Constantine, Ginger D, Simon, James A, Pickar, James H, Archer, David F, Kushner, Harvey, Bernick, Brian, Gasper, Gina, Graham, Shelli, Mirkin, Sebastian

“…OBJECTIVE:To evaluate the safety and efficacy of TX-004HR vaginal estradiol soft-gel capsules for moderate-to-severe dyspareunia associated with postmenopausal…”
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